STRINGSTRING
KDR KDR REM1 REM1 SRC SRC AKT2 AKT2 PLCG1 PLCG1 NFATC2 NFATC2 PIK3CA PIK3CA RAF1 RAF1 RAC1 RAC1 CASP9 CASP9 M3YX33_MUSPF M3YX33_MUSPF HSPB1 HSPB1 AKT3 AKT3 M3YWA8_MUSPF M3YWA8_MUSPF SH2D7 SH2D7 PIK3R1 PIK3R1 PRKCA PRKCA SPHK1 SPHK1 PPP1R14B PPP1R14B M3YNJ8_MUSPF M3YNJ8_MUSPF MAPKAPK3 MAPKAPK3 BAD BAD VEGFA VEGFA RAC2 RAC2 MAPK3 MAPK3 PRKCB PRKCB TGFB1I1 TGFB1I1 LRRC45 LRRC45 RAC3 RAC3 PLA2G4A PLA2G4A PTGS2 PTGS2 M3YH29_MUSPF M3YH29_MUSPF KRAS KRAS PRKCG PRKCG SHC2 SHC2 MAPKAPK2 MAPKAPK2 PLA2G4F PLA2G4F PLA2G4D PLA2G4D PLA2G4E PLA2G4E PPP3CA PPP3CA PLCG2 PLCG2 M3YCN4_MUSPF M3YCN4_MUSPF JMJD7 JMJD7 PIK3CB PIK3CB GEM GEM NOS3 NOS3 M3Y4E6_MUSPF M3Y4E6_MUSPF PIK3CD PIK3CD CSDE1 CSDE1 M3Y2Z6_MUSPF M3Y2Z6_MUSPF RRAD RRAD M3Y027_MUSPF M3Y027_MUSPF M3XYN0_MUSPF M3XYN0_MUSPF MAPK13 MAPK13 SH2D2A SH2D2A MAPK14 MAPK14 SPHK2 SPHK2 PPP3CC PPP3CC PPP3CB PPP3CB MAPK1 MAPK1 PXN PXN MAPK12 MAPK12 MAPK11 MAPK11 AKT1 AKT1 PTK2 PTK2 M3XRJ3_MUSPF M3XRJ3_MUSPF MAP2K1 MAP2K1 LPXN LPXN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1355 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa)
SRCTyrosine-protein kinase. (536 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
NFATC2Nuclear factor of activated T cells 2. (912 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (644 aa)
RAC1Rac family small GTPase 1. (167 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (451 aa)
M3YX33_MUSPFUncharacterized protein. (191 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (207 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
M3YWA8_MUSPFUncharacterized protein. (726 aa)
SH2D7SH2 domain containing 7. (460 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (688 aa)
SPHK1Sphingosine kinase 1. (386 aa)
PPP1R14BProtein phosphatase 1 regulatory inhibitor subunit 14B. (145 aa)
M3YNJ8_MUSPFUncharacterized protein. (461 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (384 aa)
BADBCL2 associated agonist of cell death. (168 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (398 aa)
RAC2Rac family small GTPase 2. (192 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (399 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (577 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (470 aa)
LRRC45Leucine rich repeat containing 45. (670 aa)
RAC3Rac family small GTPase 3. (160 aa)
PLA2G4APhospholipase A2. (749 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
M3YH29_MUSPFUncharacterized protein. (180 aa)
KRASKRAS proto-oncogene, GTPase. (208 aa)
PRKCGNon-specific serine/threonine protein kinase. (569 aa)
SHC2Uncharacterized protein. (539 aa)
MAPKAPK2MAPK activated protein kinase 2. (319 aa)
PLA2G4FPhospholipase A2. (847 aa)
PLA2G4DPhospholipase A2. (829 aa)
PLA2G4EPhospholipase A2. (810 aa)
PPP3CASerine/threonine-protein phosphatase. (461 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1266 aa)
M3YCN4_MUSPFPhospholipase A2. (783 aa)
JMJD7Jumonji domain containing 7. (316 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (296 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1211 aa)
M3Y4E6_MUSPFUncharacterized protein. (160 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
CSDE1Cold shock domain containing E1. (784 aa)
M3Y2Z6_MUSPFUncharacterized protein. (189 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
M3Y027_MUSPFProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
M3XYN0_MUSPFUncharacterized protein. (192 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
SH2D2ASH2 domain containing 2A. (424 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
SPHK2Sphingosine kinase 2. (673 aa)
PPP3CCSerine/threonine-protein phosphatase. (525 aa)
PPP3CBSerine/threonine-protein phosphatase. (479 aa)
MAPK1Mitogen-activated protein kinase. (333 aa)
PXNPaxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (590 aa)
MAPK12Mitogen-activated protein kinase. (287 aa)
MAPK11Mitogen-activated protein kinase. (434 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
M3XRJ3_MUSPFUncharacterized protein. (182 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
LPXNLeupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (414 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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