STRINGSTRING
ACTL8 ACTL8 AXIN1 AXIN1 YWHAG YWHAG WNT4 WNT4 M3YWQ4_MUSPF M3YWQ4_MUSPF SERPINE1 SERPINE1 LIMD1 LIMD1 STK3 STK3 YWHAZ YWHAZ FZD6 FZD6 WNT10B WNT10B WNT1 WNT1 CCN2 CCN2 AXIN2 AXIN2 M3YSK2_MUSPF M3YSK2_MUSPF DVL1 DVL1 M3YSB8_MUSPF M3YSB8_MUSPF BMP7 BMP7 CRB2 CRB2 LLGL2 LLGL2 M3YQX5_MUSPF M3YQX5_MUSPF LDAH LDAH GDF7 GDF7 YWHAE YWHAE CCND3 CCND3 NF2 NF2 YWHAQ YWHAQ BIRC5 BIRC5 ID2 ID2 TEAD1 TEAD1 M3YNT9_MUSPF M3YNT9_MUSPF WWC1 WWC1 RASSF1 RASSF1 FBXW11 FBXW11 YWHAH YWHAH APC APC TGFBR2 TGFBR2 M3YKK2_MUSPF M3YKK2_MUSPF M3YKJ5_MUSPF M3YKJ5_MUSPF ACTG1 ACTG1 CTNNB1 CTNNB1 M3YI89_MUSPF M3YI89_MUSPF CSNK1D CSNK1D SNAI2 SNAI2 DLG4 DLG4 DVL2 DVL2 FZD4 FZD4 CRB1 CRB1 ITGB2 ITGB2 PPP2CB PPP2CB TCF7 TCF7 PPP2CA PPP2CA WNT8A WNT8A MOB1B MOB1B TEAD4 TEAD4 M3YD44_MUSPF M3YD44_MUSPF CTNNA1 CTNNA1 AFP AFP M3YCX1_MUSPF M3YCX1_MUSPF RASSF6 RASSF6 AREG AREG LEF1 LEF1 BMPR1A BMPR1A LRRC1 LRRC1 WNT11 WNT11 SMAD4 SMAD4 GDF6 GDF6 TCF7L1 TCF7L1 CTNNA2 CTNNA2 M3YAW2_MUSPF M3YAW2_MUSPF GSK3B GSK3B LOC106003358 LOC106003358 M3Z6K8_MUSPF M3Z6K8_MUSPF FZD1 FZD1 FZD2 FZD2 FZD5 FZD5 FZD7 FZD7 LATS1 LATS1 WNT5B WNT5B PPP1CB PPP1CB ID1 ID1 GDF5 GDF5 YWHAB YWHAB WNT9B WNT9B TGFBR1 TGFBR1 SMAD1 SMAD1 M3Y696_MUSPF M3Y696_MUSPF WNT16 WNT16 MPP5 MPP5 CDH1 CDH1 AJUBA AJUBA WNT2 WNT2 BIRC2 BIRC2 BIRC3 BIRC3 YAP1 YAP1 PPP2R2C PPP2R2C TP73 TP73 M3Y7U3_MUSPF M3Y7U3_MUSPF PATJ PATJ PRKCZ PRKCZ PPP2R2B PPP2R2B MOB1A MOB1A FGF1 FGF1 DLG2 DLG2 SCRIB SCRIB APC2 APC2 WNT3 WNT3 PARD6A PARD6A BMP2 BMP2 PARD3 PARD3 BMP4 BMP4 FRMD6 FRMD6 SAV1 SAV1 WNT2B WNT2B M3Y0R3_MUSPF M3Y0R3_MUSPF DLG3 DLG3 CCND1 CCND1 FZD10 FZD10 TGFB2 TGFB2 AMOT AMOT TP53BP2 TP53BP2 DLG5 DLG5 PPP1CA PPP1CA DLG1 DLG1 TEAD3 TEAD3 PPP2R1B PPP2R1B PPP2R2A PPP2R2A NKD1 NKD1 BMP5 BMP5 TEAD2 TEAD2 WWTR1 WWTR1 DVL3 DVL3 M3XTE0_MUSPF M3XTE0_MUSPF PPP2R2D PPP2R2D PPP1CC PPP1CC BMPR1B BMPR1B M3XSG3_MUSPF M3XSG3_MUSPF TCF7L2 TCF7L2 SOX3 SOX3 M3XR07_MUSPF M3XR07_MUSPF MYC MYC GLI2 GLI2 FZD3 FZD3 WNT3A WNT3A WNT9A WNT9A SMAD2 SMAD2 SMAD7 SMAD7 LATS2 LATS2 BMP6 BMP6 BMPR2 BMPR2 SMAD3 SMAD3 LLGL1 LLGL1 MYO15A MYO15A TGFB1 TGFB1 PARD6B PARD6B M3Z176_MUSPF M3Z176_MUSPF PPP2R1A PPP2R1A WNT7A WNT7A PRKCI PRKCI WNT8B WNT8B BTRC BTRC WNT5A WNT5A ACTB ACTB WNT10A WNT10A WNT6 WNT6 WNT7B WNT7B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACTL8Actin like 8; Belongs to the actin family. (366 aa)
AXIN1Axin 1. (862 aa)
YWHAGTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (247 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
M3YWQ4_MUSPFUncharacterized protein; Belongs to the actin family. (338 aa)
SERPINE1Serpin peptidase inhibitor, clade E, member 1; Belongs to the serpin family. (400 aa)
LIMD1LIM domains containing 1. (671 aa)
STK3Serine/threonine kinase 3. (418 aa)
YWHAZTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (245 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (736 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (340 aa)
CCN2Cellular communication network factor 2. (349 aa)
AXIN2Axin 2. (842 aa)
M3YSK2_MUSPFTGF_BETA_2 domain-containing protein. (291 aa)
DVL1Dishevelled segment polarity protein 1. (691 aa)
M3YSB8_MUSPFTGF_BETA_2 domain-containing protein. (351 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
CRB2Crumbs cell polarity complex component 2. (1195 aa)
LLGL2LLGL scribble cell polarity complex component 2. (1022 aa)
M3YQX5_MUSPFUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1742 aa)
LDAHLipid droplet associated hydrolase. (325 aa)
GDF7Growth differentiation factor 7. (382 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (251 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (294 aa)
NF2Neurofibromin 2. (591 aa)
YWHAQTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta; Belongs to the 14-3-3 family. (245 aa)
BIRC5Baculoviral IAP repeat containing 5. (142 aa)
ID2Inhibitor of DNA binding 2. (134 aa)
TEAD1TEA domain transcription factor 1. (436 aa)
M3YNT9_MUSPFProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (431 aa)
WWC1WW and C2 domain containing 1. (1110 aa)
RASSF1Ras association domain family member 1. (272 aa)
FBXW11F-box and WD repeat domain containing 11. (527 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (246 aa)
APCAPC regulator of WNT signaling pathway. (2862 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (445 aa)
M3YKK2_MUSPFUncharacterized protein. (220 aa)
M3YKJ5_MUSPFUncharacterized protein. (247 aa)
ACTG1Actin gamma 1. (375 aa)
CTNNB1Catenin beta 1. (781 aa)
M3YI89_MUSPFUncharacterized protein. (271 aa)
CSNK1DCasein kinase 1 delta. (352 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (724 aa)
DVL2Dishevelled segment polarity protein 2. (734 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
CRB1Crumbs cell polarity complex component 1. (1411 aa)
ITGB2Integrin beta. (782 aa)
PPP2CBSerine/threonine-protein phosphatase. (284 aa)
TCF7Transcription factor 7. (339 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
MOB1BMOB kinase activator 1B. (211 aa)
TEAD4TEA domain transcription factor 4. (361 aa)
M3YD44_MUSPFCyclin N-terminal domain-containing protein; Belongs to the cyclin family. (291 aa)
CTNNA1Catenin alpha 1. (930 aa)
AFPAlpha fetoprotein. (609 aa)
M3YCX1_MUSPFUncharacterized protein. (625 aa)
RASSF6Ras association domain family member 6. (336 aa)
AREGAmphiregulin. (283 aa)
LEF1Lymphoid enhancer binding factor 1. (400 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa)
LRRC1Leucine rich repeat containing 1. (524 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
GDF6Growth differentiation factor 6. (434 aa)
TCF7L1Transcription factor 7 like 1. (490 aa)
CTNNA2Catenin alpha 2. (521 aa)
M3YAW2_MUSPFUncharacterized protein. (429 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (420 aa)
LOC106003358Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (544 aa)
M3Z6K8_MUSPFG_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor Fz/Smo family. (397 aa)
FZD1Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (642 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (550 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (602 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
LATS1Large tumor suppressor kinase 1. (1127 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (406 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (154 aa)
GDF5Growth differentiation factor 5. (500 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (204 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (480 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
M3Y696_MUSPFUncharacterized protein. (492 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
MPP5Membrane palmitoylated protein 5; Belongs to the MAGUK family. (675 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (885 aa)
AJUBAAjuba LIM protein. (548 aa)
WNT2Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa)
BIRC2Baculoviral IAP repeat containing 2. (570 aa)
BIRC3Baculoviral IAP repeat containing 3. (604 aa)
YAP1Yes associated protein 1. (325 aa)
PPP2R2CSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (710 aa)
M3Y7U3_MUSPFUncharacterized protein. (240 aa)
PATJPATJ crumbs cell polarity complex component. (1803 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (582 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (501 aa)
MOB1AMOB kinase activator 1A. (216 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
DLG2Uncharacterized protein. (833 aa)
SCRIBScribble planar cell polarity protein. (1523 aa)
APC2APC regulator of WNT signaling pathway 2. (2481 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
PARD6APar-6 family cell polarity regulator alpha. (346 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
PARD3Par-3 family cell polarity regulator. (1356 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
FRMD6FERM domain containing 6. (614 aa)
SAV1Salvador family WW domain containing protein 1. (384 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
M3Y0R3_MUSPFUncharacterized protein. (201 aa)
DLG3Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (849 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
FZD10Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
TGFB2Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...] (414 aa)
AMOTAngiomotin. (1062 aa)
TP53BP2Tumor protein p53 binding protein 2. (1168 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1922 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (927 aa)
TEAD3TEA domain transcription factor 3. (403 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (789 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (487 aa)
NKD1NKD inhibitor of WNT signaling pathway 1. (425 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
TEAD2TEA domain transcription factor 2. (545 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
DVL3Dishevelled segment polarity protein 3. (718 aa)
M3XTE0_MUSPFUncharacterized protein; Belongs to the actin family. (348 aa)
PPP2R2DSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (423 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (514 aa)
M3XSG3_MUSPFCTNNB1_binding domain-containing protein. (169 aa)
TCF7L2Transcription factor 7 like 2. (514 aa)
SOX3SRY-box transcription factor 3. (303 aa)
M3XR07_MUSPFUncharacterized protein; Belongs to the actin family. (362 aa)
MYCV-myc myelocytomatosis viral oncoprotein-like protein. (453 aa)
GLI2GLI family zinc finger 2. (1473 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (451 aa)
SMAD2Mothers against decapentaplegic homolog. (495 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
LATS2Non-specific serine/threonine protein kinase. (1084 aa)
BMP6Bone morphogenetic protein 6. (426 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1045 aa)
SMAD3Mothers against decapentaplegic homolog. (414 aa)
LLGL1LLGL scribble cell polarity complex component 1. (1074 aa)
MYO15AMyosin XVA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (3438 aa)
TGFB1Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
PARD6BPar-6 family cell polarity regulator beta. (391 aa)
M3Z176_MUSPF14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (221 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (590 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (638 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (567 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (383 aa)
ACTBActin beta. (375 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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