STRINGSTRING
TAB2 TAB2 MMP9 MMP9 TBK1 TBK1 IFNG IFNG IL17RC IL17RC IL17RE IL17RE CHUK CHUK IL17RB IL17RB NFKBIA NFKBIA TRAF5 TRAF5 M3YV99_MUSPF M3YV99_MUSPF CSF3 CSF3 TNFAIP3 TNFAIP3 CCL7 CCL7 CCL2 CCL2 IL17B IL17B TRAF4 TRAF4 IL6 IL6 LCN2 LCN2 IKBKB IKBKB MAPK3 MAPK3 HSP90AB1 HSP90AB1 IKBKE IKBKE HSP90B1 HSP90B1 TRAF6 TRAF6 RELA RELA CSF2 CSF2 FOSL1 FOSL1 TNF TNF CASP3 CASP3 TRAF2 TRAF2 PTGS2 PTGS2 IL1B IL1B USP25 USP25 IL13 IL13 IL4 IL4 M3YFM7_MUSPF M3YFM7_MUSPF IKBKG IKBKG NFKB1 NFKB1 M3YCY6_MUSPF M3YCY6_MUSPF CXCL8 CXCL8 FOS FOS MAPK8 MAPK8 MAP3K7 MAP3K7 IL17A IL17A IL17F IL17F MAPK4 MAPK4 CXCL10 CXCL10 M3YAG4_MUSPF M3YAG4_MUSPF S100A8 S100A8 GSK3B GSK3B IL17C IL17C MAPK15 MAPK15 ELAVL1 ELAVL1 MAPK6 MAPK6 M3Y672_MUSPF M3Y672_MUSPF MMP1 MMP1 LOC101688701 LOC101688701 MMP12 MMP12 CCL20 CCL20 MAPK9 MAPK9 CASP8 CASP8 MAPK7 MAPK7 MMP13 MMP13 JUN JUN JUND JUND IL25 IL25 FOSB FOSB TRADD TRADD FADD FADD CCL17 CCL17 MAPK13 MAPK13 MAPK14 MAPK14 MAPK1 MAPK1 HSP90AA1 HSP90AA1 TRAF3 TRAF3 TAB3 TAB3 M3XTU8_MUSPF M3XTU8_MUSPF MAPK12 MAPK12 MAPK10 MAPK10 MAPK11 MAPK11 ANAPC5 ANAPC5 M3XSM2_MUSPF M3XSM2_MUSPF CEBPB CEBPB IL17RA IL17RA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
MMP9Matrix metallopeptidase 9. (704 aa)
TBK1TANK-binding kinase 1. (729 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (166 aa)
IL17RCInterleukin 17 receptor C. (713 aa)
IL17REInterleukin 17 receptor E. (670 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
IL17RBInterleukin 17 receptor B. (494 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa)
M3YV99_MUSPFUncharacterized protein. (248 aa)
CSF3Colony stimulating factor 3. (204 aa)
TNFAIP3TNF alpha induced protein 3. (790 aa)
CCL7C-C motif chemokine. (99 aa)
CCL2C-C motif chemokine. (101 aa)
IL17BInterleukin 17B. (180 aa)
TRAF4TNF receptor-associated factor. (470 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (210 aa)
LCN2Lipocalin 2; Belongs to the calycin superfamily. Lipocalin family. (199 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (399 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (724 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (719 aa)
HSP90B1Heat shock protein 90 beta family member 1. (803 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
RELARELA proto-oncogene, NF-kB subunit. (511 aa)
CSF2Colony stimulating factor 2. (148 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (271 aa)
TNFTumor necrosis factor alpha; Belongs to the tumor necrosis factor family. (233 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (569 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (168 aa)
USP25Ubiquitin specific peptidase 25; Belongs to the peptidase C19 family. (1127 aa)
IL13Interleukin 13. (128 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (132 aa)
M3YFM7_MUSPFSEFIR domain-containing protein. (557 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (412 aa)
NFKB1Nuclear factor kappa B subunit 1. (971 aa)
M3YCY6_MUSPFSEFIR domain-containing protein. (532 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (446 aa)
MAPK8Mitogen-activated protein kinase. (397 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
IL17AInterleukin 17A. (153 aa)
IL17FUncharacterized protein. (140 aa)
MAPK4Mitogen-activated protein kinase 4. (583 aa)
CXCL10C-X-C motif chemokine. (98 aa)
M3YAG4_MUSPFEF-hand domain-containing protein; Belongs to the S-100 family. (189 aa)
S100A8Protein S100; Belongs to the S-100 family. (89 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (420 aa)
IL17CInterleukin 17C. (197 aa)
MAPK15Mitogen-activated protein kinase. (550 aa)
ELAVL1ELAV-like protein; Belongs to the RRM elav family. (326 aa)
MAPK6Mitogen-activated protein kinase 6. (624 aa)
M3Y672_MUSPFUncharacterized protein. (100 aa)
MMP1Matrix metallopeptidase 1. (470 aa)
LOC101688701ZnMc domain-containing protein. (476 aa)
MMP12Matrix metallopeptidase 12. (493 aa)
CCL20C-C motif chemokine. (97 aa)
MAPK9Mitogen-activated protein kinase. (398 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (484 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
MMP13Matrix metallopeptidase 13. (511 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
JUNDJunD proto-oncogene, AP-1 transcription factor subunit. (347 aa)
IL25Interleukin 25. (169 aa)
FOSBFosB proto-oncogene, AP-1 transcription factor subunit. (338 aa)
TRADDTNFRSF1A associated via death domain. (314 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (216 aa)
CCL17C-C motif chemokine. (99 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MAPK1Mitogen-activated protein kinase. (333 aa)
HSP90AA1HATPase_c domain-containing protein. (679 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (569 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (715 aa)
M3XTU8_MUSPFUncharacterized protein. (72 aa)
MAPK12Mitogen-activated protein kinase. (287 aa)
MAPK10Mitogen-activated protein kinase. (384 aa)
MAPK11Mitogen-activated protein kinase. (434 aa)
ANAPC5Anaphase promoting complex subunit 5. (711 aa)
M3XSM2_MUSPFUncharacterized protein. (164 aa)
CEBPBCCAAT/enhancer-binding protein. (346 aa)
IL17RAInterleukin 17 receptor A. (864 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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