STRINGSTRING
JAG1 JAG1 LAT LAT IKBKB IKBKB IL2RB IL2RB MAPK3 MAPK3 NFKBIE NFKBIE STAT4 STAT4 STAT1 STAT1 M3YLR8_MUSPF M3YLR8_MUSPF MAML2 MAML2 RELA RELA NOTCH1 NOTCH1 ZAP70 ZAP70 M3YH07_MUSPF M3YH07_MUSPF STAT5B STAT5B STAT5A STAT5A IL13 IL13 IL4 IL4 IKBKG IKBKG M3YE13_MUSPF M3YE13_MUSPF M3YDZ3_MUSPF M3YDZ3_MUSPF PPP3CA PPP3CA NFKB1 NFKB1 FOS FOS MAPK8 MAPK8 DLL4 DLL4 M3YB13_MUSPF M3YB13_MUSPF M3YAZ8_MUSPF M3YAZ8_MUSPF M3YAY8_MUSPF M3YAY8_MUSPF TRBV25-1 TRBV25-1 M3YAV2_MUSPF M3YAV2_MUSPF M3YAT2_MUSPF M3YAT2_MUSPF TRAV18 TRAV18 M3Y7K5_MUSPF M3Y7K5_MUSPF M3Y7D3_MUSPF M3Y7D3_MUSPF M3Y7C9_MUSPF M3Y7C9_MUSPF M3Y779_MUSPF M3Y779_MUSPF DLL1 DLL1 NFATC3 NFATC3 TYK2 TYK2 IL4R IL4R M3Y4E6_MUSPF M3Y4E6_MUSPF JAK2 JAK2 M3XZW3_MUSPF M3XZW3_MUSPF CD3G CD3G CD3D CD3D CD3E CD3E MAPK13 MAPK13 MAPK14 MAPK14 PPP3CC PPP3CC PPP3CB PPP3CB M3XVL5_MUSPF M3XVL5_MUSPF M3XVL3_MUSPF M3XVL3_MUSPF MAPK1 MAPK1 M3XVL1_MUSPF M3XVL1_MUSPF M3XVK5_MUSPF M3XVK5_MUSPF IL12A IL12A MAPK12 MAPK12 MAPK10 MAPK10 MAPK11 MAPK11 M3XSG8_MUSPF M3XSG8_MUSPF M3XSG7_MUSPF M3XSG7_MUSPF HLA-DPA1 HLA-DPA1 HLA-DOA HLA-DOA HLA-DMA HLA-DMA M3XS76_MUSPF M3XS76_MUSPF M3XS58_MUSPF M3XS58_MUSPF STAT6 STAT6 NOTCH2 NOTCH2 IFNGR2 IFNGR2 IL12RB2 IL12RB2 JAK1 JAK1 MAML1 MAML1 MAPK9 MAPK9 JUN JUN NFKBIB NFKBIB DLL3 DLL3 PLCG1 PLCG1 RBPJL RBPJL NFATC2 NFATC2 IFNG IFNG IL2 IL2 CHUK CHUK CD4 CD4 RBPJ RBPJ NFATC1 NFATC1 GATA3 GATA3 PRKCQ PRKCQ IL2RA IL2RA NFKBIA NFKBIA MAML3 MAML3 NOTCH3 NOTCH3 RUNX3 RUNX3 JAK3 JAK3 IL12RB1 IL12RB1 CD247 CD247 TBX21 TBX21 LCK LCK LOC101678178 LOC101678178 IFNGR1 IFNGR1 IL12B IL12B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
LATLinker for activation of T cells. (260 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
IL2RBInterleukin 2 receptor subunit beta. (554 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (399 aa)
NFKBIENFKB inhibitor epsilon. (394 aa)
STAT4Signal transducer and activator of transcription. (827 aa)
STAT1Signal transducer and activator of transcription. (750 aa)
M3YLR8_MUSPFRHD domain-containing protein. (249 aa)
MAML2Mastermind like transcriptional coactivator 2. (1094 aa)
RELARELA proto-oncogene, NF-kB subunit. (511 aa)
NOTCH1Notch receptor 1. (2119 aa)
ZAP70Tyrosine-protein kinase. (616 aa)
M3YH07_MUSPFIg-like domain-containing protein. (265 aa)
STAT5BSignal transducer and activator of transcription. (691 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
IL13Interleukin 13. (128 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (132 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (412 aa)
M3YE13_MUSPFIg-like domain-containing protein. (233 aa)
M3YDZ3_MUSPFMHC_II_alpha domain-containing protein. (236 aa)
PPP3CASerine/threonine-protein phosphatase. (461 aa)
NFKB1Nuclear factor kappa B subunit 1. (971 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (446 aa)
MAPK8Mitogen-activated protein kinase. (397 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
M3YB13_MUSPFIg-like domain-containing protein. (159 aa)
M3YAZ8_MUSPFIg-like domain-containing protein. (158 aa)
M3YAY8_MUSPFIg-like domain-containing protein. (227 aa)
TRBV25-1T cell receptor beta variable 25-1. (125 aa)
M3YAV2_MUSPFIg-like domain-containing protein. (141 aa)
M3YAT2_MUSPFIg-like domain-containing protein. (186 aa)
TRAV18T cell receptor alpha variable 18. (159 aa)
M3Y7K5_MUSPFIg-like domain-containing protein. (163 aa)
M3Y7D3_MUSPFDUF1968 domain-containing protein. (157 aa)
M3Y7C9_MUSPFIg-like domain-containing protein. (266 aa)
M3Y779_MUSPFIg-like domain-containing protein. (269 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (602 aa)
NFATC3Nuclear factor of activated T cells 3. (1037 aa)
TYK2Tyrosine-protein kinase. (1182 aa)
IL4RInterleukin 4 receptor. (805 aa)
M3Y4E6_MUSPFUncharacterized protein. (160 aa)
JAK2Tyrosine-protein kinase. (1130 aa)
M3XZW3_MUSPFFibronectin type-III domain-containing protein. (374 aa)
CD3GT-cell surface glycoprotein CD3 gamma chain. (180 aa)
CD3DCD3d molecule. (169 aa)
CD3ECD3 epsilon antigen. (186 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
PPP3CCSerine/threonine-protein phosphatase. (525 aa)
PPP3CBSerine/threonine-protein phosphatase. (479 aa)
M3XVL5_MUSPFUncharacterized protein. (105 aa)
M3XVL3_MUSPFUncharacterized protein. (168 aa)
MAPK1Mitogen-activated protein kinase. (333 aa)
M3XVL1_MUSPFUncharacterized protein. (68 aa)
M3XVK5_MUSPFUncharacterized protein. (1274 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (222 aa)
MAPK12Mitogen-activated protein kinase. (287 aa)
MAPK10Mitogen-activated protein kinase. (384 aa)
MAPK11Mitogen-activated protein kinase. (434 aa)
M3XSG8_MUSPFUncharacterized protein. (429 aa)
M3XSG7_MUSPFUncharacterized protein. (233 aa)
HLA-DPA1Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (242 aa)
HLA-DOAMajor histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (250 aa)
HLA-DMAMajor histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (261 aa)
M3XS76_MUSPFIg-like domain-containing protein. (263 aa)
M3XS58_MUSPFIg-like domain-containing protein. (171 aa)
STAT6Signal transducer and activator of transcription. (844 aa)
NOTCH2Notch receptor 2. (2471 aa)
IFNGR2Interferon gamma receptor 2. (341 aa)
IL12RB2Interleukin 12 receptor subunit beta 2. (766 aa)
JAK1Tyrosine-protein kinase. (1153 aa)
MAML1Mastermind like transcriptional coactivator 1. (789 aa)
MAPK9Mitogen-activated protein kinase. (398 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
NFKBIBNFKB inhibitor beta. (354 aa)
DLL3Delta like canonical Notch ligand 3. (590 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
RBPJLRecombination signal binding protein for immunoglobulin kappa J region like. (530 aa)
NFATC2Nuclear factor of activated T cells 2. (912 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (166 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (152 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
CD4CD4. (462 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (487 aa)
NFATC1Nuclear factor of activated T cells 1. (701 aa)
GATA3GATA binding protein 3. (444 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
IL2RAInterleukin 2 receptor subunit alpha. (267 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
MAML3Mastermind like transcriptional coactivator 3. (920 aa)
NOTCH3Notch receptor 3. (2305 aa)
RUNX3Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (412 aa)
JAK3Tyrosine-protein kinase. (1107 aa)
IL12RB1Interleukin 12 receptor subunit beta 1. (716 aa)
CD247CD247 molecule. (185 aa)
TBX21T-box transcription factor 21. (535 aa)
LCKTyrosine-protein kinase. (509 aa)
LOC101678178Ig-like domain-containing protein; Belongs to the MHC class II family. (196 aa)
IFNGR1Interferon gamma receptor 1. (474 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (331 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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