(74 nodes) Long-term potentiation network (Mustela putorius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GNA11	G protein subunit alpha 11. (334 aa)
	PPP3CC	Serine/threonine-protein phosphatase. (525 aa)
	PPP3CB	Serine/threonine-protein phosphatase. (479 aa)
	BRAF	B-Raf proto-oncogene, serine/threonine kinase. (715 aa)
	RPS6KA3	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (741 aa)
	CAMK2G	Calcium/calmodulin dependent protein kinase II gamma. (561 aa)
	MAPK1	Mitogen-activated protein kinase. (333 aa)
	PRKACA	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3. (2609 aa)
	PPP1CC	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
	M3XMV4_MUSPF	Uncharacterized protein. (466 aa)
	MAP2K1	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
	CALML4	Calmodulin like 4. (153 aa)
	M3YA76_MUSPF	Protein kinase domain-containing protein. (533 aa)
	PLCB2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1187 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (461 aa)
	M3YEN4_MUSPF	BZIP domain-containing protein. (358 aa)
	PRKCG	Non-specific serine/threonine protein kinase. (569 aa)
	KRAS	KRAS proto-oncogene, GTPase. (208 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
	GRM5	Glutamate metabotropic receptor 5. (987 aa)
	M3YH29_MUSPF	Uncharacterized protein. (180 aa)
	GRIN2B	Glutamate ionotropic receptor NMDA type subunit 2B. (1550 aa)
	CALM2	Calmodulin 2; Belongs to the calmodulin family. (149 aa)
	PRKCB	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (577 aa)
	GNAQ	G protein subunit alpha q. (301 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (399 aa)
	M3YMK1_MUSPF	Protein kinase domain-containing protein. (105 aa)
	M3YMK5_MUSPF	Protein kinase domain-containing protein. (185 aa)
	M3YMU3_MUSPF	MIR domain-containing protein. (78 aa)
	PLCB3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1233 aa)
	ARAF	V-raf murine sarcoma 3611 viral oncoprotein-like protein. (606 aa)
	M3YPM9_MUSPF	BZIP domain-containing protein. (351 aa)
	GRIA1	Glutamate ionotropic receptor AMPA type subunit 1. (906 aa)
	ARSI	Arylsulfatase family member I. (575 aa)
	CAMK2A	Calcium/calmodulin dependent protein kinase II alpha. (679 aa)
	GRIN2C	Glutamate ionotropic receptor NMDA type subunit 2C. (1109 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (688 aa)
	GRIN2A	Glutamate ionotropic receptor NMDA type subunit 2A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1307 aa)
	GRIN1	Glutamate ionotropic receptor NMDA type subunit 1. (959 aa)
	CREBBP	CREB binding protein. (2442 aa)
	RPS6KA1	Ribosomal protein S6 kinase. (719 aa)
	EP300	E1A binding protein p300. (2425 aa)
	M3YZ57_MUSPF	Uncharacterized protein. (168 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1. (2709 aa)
	RAF1	Raf-1 proto-oncogene, serine/threonine kinase. (644 aa)
	RAP1B	RAP1B, member of RAS oncogene family. (184 aa)
	PPP1CB	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
	GRM1	Glutamate metabotropic receptor 1. (906 aa)
	M3Z2Z7_MUSPF	Uncharacterized protein. (204 aa)
	CACNA1C	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1479 aa)
	ADCY1	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1130 aa)
	CAMK2B	Calcium/calmodulin dependent protein kinase II beta. (610 aa)
	CALML5	Calmodulin like 5. (149 aa)
	M3Z785_MUSPF	Uncharacterized protein; Belongs to the calmodulin family. (149 aa)
	CALM1	Calmodulin 1; Belongs to the calmodulin family. (156 aa)
	CALML6	Calmodulin like 6. (156 aa)
	RPS6KA2	Ribosomal protein S6 kinase. (733 aa)
	PLCB4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1096 aa)
	RPS6KA6	Ribosomal protein S6 kinase. (794 aa)
	M3Y4E6_MUSPF	Uncharacterized protein. (160 aa)
	GRIA2	Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
	PRKACB	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
	CSDE1	Cold shock domain containing E1. (784 aa)
	M3Y2Z6_MUSPF	Uncharacterized protein. (189 aa)
	PPP1R1A	Protein phosphatase 1 regulatory inhibitor subunit 1A. (171 aa)
	CALM3	Calmodulin 3; Belongs to the calmodulin family. (151 aa)
	RAP1A	RAP1A, member of RAS oncogene family. (188 aa)
	M3Y027_MUSPF	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
	GRIN2D	Glutamate ionotropic receptor NMDA type subunit 2D; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (738 aa)
	PPP1CA	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
	M3XXC7_MUSPF	Uncharacterized protein. (93 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY8	ENSMPUP00000018070	ENSMPUP00000001384	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.855
ADCY1	CALM1	ENSMPUP00000018070	ENSMPUP00000008029	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin 1; Belongs to the calmodulin family.	0.756
ADCY1	CALM2	ENSMPUP00000018070	ENSMPUP00000011969	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin 2; Belongs to the calmodulin family.	0.756
ADCY1	CALM3	ENSMPUP00000018070	ENSMPUP00000005223	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin 3; Belongs to the calmodulin family.	0.756
ADCY1	CALML4	ENSMPUP00000018070	ENSMPUP00000000268	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin like 4.	0.882
ADCY1	CALML5	ENSMPUP00000018070	ENSMPUP00000019445	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin like 5.	0.948
ADCY1	CALML6	ENSMPUP00000018070	ENSMPUP00000007945	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin like 6.	0.949
ADCY1	CAMK2A	ENSMPUP00000018070	ENSMPUP00000013741	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin dependent protein kinase II alpha.	0.849
ADCY1	CAMK2B	ENSMPUP00000018070	ENSMPUP00000018087	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin dependent protein kinase II beta.	0.847
ADCY1	CAMK2G	ENSMPUP00000018070	ENSMPUP00000003346	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin dependent protein kinase II gamma.	0.843
ADCY1	M3XMV4_MUSPF	ENSMPUP00000018070	ENSMPUP00000000404	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.874
ADCY1	M3YA76_MUSPF	ENSMPUP00000018070	ENSMPUP00000008233	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase domain-containing protein.	0.860
ADCY1	M3YMK1_MUSPF	ENSMPUP00000018070	ENSMPUP00000012558	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase domain-containing protein.	0.836
ADCY1	M3YMK5_MUSPF	ENSMPUP00000018070	ENSMPUP00000012562	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase domain-containing protein.	0.836
ADCY1	M3Z785_MUSPF	ENSMPUP00000018070	ENSMPUP00000019448	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein; Belongs to the calmodulin family.	0.825
ADCY1	PRKACA	ENSMPUP00000018070	ENSMPUP00000003045	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.878
ADCY1	PRKACB	ENSMPUP00000018070	ENSMPUP00000005718	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.882
ADCY1	PRKCA	ENSMPUP00000018070	ENSMPUP00000014555	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.856
ADCY1	PRKCB	ENSMPUP00000018070	ENSMPUP00000012100	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.871
ADCY1	PRKCG	ENSMPUP00000018070	ENSMPUP00000010076	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Non-specific serine/threonine protein kinase.	0.863