STRINGSTRING
CSDE1 CSDE1 M3Y2Z6_MUSPF M3Y2Z6_MUSPF CALM3 CALM3 M3Y1L7_MUSPF M3Y1L7_MUSPF SOS2 SOS2 RAP1A RAP1A M3Y027_MUSPF M3Y027_MUSPF M3XYX1_MUSPF M3XYX1_MUSPF M3XYN0_MUSPF M3XYN0_MUSPF MATK MATK MAPK13 MAPK13 MAPK14 MAPK14 PSEN1 PSEN1 CRKL CRKL NTRK1 NTRK1 BRAF BRAF RPS6KA3 RPS6KA3 CAMK2G CAMK2G BAX BAX SORT1 SORT1 MAPK1 MAPK1 PTPN11 PTPN11 MAPK12 MAPK12 MAPK10 MAPK10 MAPK11 MAPK11 M3XSY8_MUSPF M3XSY8_MUSPF M3XSY7_MUSPF M3XSY7_MUSPF NTRK2 NTRK2 AKT1 AKT1 M3XQX1_MUSPF M3XQX1_MUSPF IRS1 IRS1 MAGED1 MAGED1 GAB1 GAB1 MAPK9 MAPK9 MAP2K1 MAP2K1 IRAK4 IRAK4 MAP2K5 MAP2K5 CALML4 CALML4 M3XLW8_MUSPF M3XLW8_MUSPF MAPK7 MAPK7 M3YWA8_MUSPF M3YWA8_MUSPF RPS6KA1 RPS6KA1 FASLG FASLG NGFR NGFR PDPK1 PDPK1 M3YUS4_MUSPF M3YUS4_MUSPF M3YUS3_MUSPF M3YUS3_MUSPF MAP3K3 MAP3K3 MAP3K5 MAP3K5 PIK3R1 PIK3R1 M3YR72_MUSPF M3YR72_MUSPF GRB2 GRB2 CAMK2A CAMK2A ARSI ARSI RHOA RHOA YWHAE YWHAE CRK CRK M3YPM9_MUSPF M3YPM9_MUSPF PPP1R14B PPP1R14B KIDINS220 KIDINS220 M3YNJ8_MUSPF M3YNJ8_MUSPF BAD BAD SH2B1 SH2B1 IKBKB IKBKB ABL1 ABL1 M3YMK5_MUSPF M3YMK5_MUSPF M3YMK1_MUSPF M3YMK1_MUSPF MAPK3 MAPK3 NFKBIE NFKBIE RAPGEF1 RAPGEF1 SHC4 SHC4 PRDM4 PRDM4 CALM2 CALM2 TRAF6 TRAF6 RELA RELA ARHGDIB ARHGDIB BDNF BDNF RIPK2 RIPK2 M3YH29_MUSPF M3YH29_MUSPF SOS1 SOS1 KRAS KRAS SHC2 SHC2 MAPKAPK2 MAPKAPK2 M3YEN4_MUSPF M3YEN4_MUSPF FOXO3 FOXO3 NFKB1 NFKB1 PLCG2 PLCG2 MAPK8 MAPK8 PIK3CB PIK3CB IRAK1 IRAK1 TP53 TP53 SHC3 SHC3 ZNF274 ZNF274 GSK3B GSK3B M3YA76_MUSPF M3YA76_MUSPF CALM1 CALM1 RPS6KA5 RPS6KA5 MAP2K7 MAP2K7 CALML6 CALML6 MAP3K1 MAP3K1 TP73 TP73 RPS6KA2 RPS6KA2 RPS6KA6 RPS6KA6 PIK3CD PIK3CD SHC1 SHC1 JUN JUN NTF3 NTF3 M3Z785_MUSPF M3Z785_MUSPF CALML5 CALML5 NGF NGF NTF4 NTF4 BEX3 BEX3 CAMK2B CAMK2B NFKBIB NFKBIB AKT2 AKT2 PLCG1 PLCG1 IRAK3 IRAK3 RAP1B RAP1B FRS2 FRS2 M3Z176_MUSPF M3Z176_MUSPF CSK CSK PIK3CA PIK3CA RAF1 RAF1 IRAK2 IRAK2 PRKCD PRKCD BCL2 BCL2 NFKBIA NFKBIA M3YX33_MUSPF M3YX33_MUSPF SH2B2 SH2B2 PSEN2 PSEN2 NTRK3 NTRK3 AKT3 AKT3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CSDE1Cold shock domain containing E1. (784 aa)
M3Y2Z6_MUSPFUncharacterized protein. (189 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (151 aa)
M3Y1L7_MUSPFSprT-like domain-containing protein. (535 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1281 aa)
RAP1ARAP1A, member of RAS oncogene family. (188 aa)
M3Y027_MUSPFProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
M3XYX1_MUSPFDZF domain-containing protein. (952 aa)
M3XYN0_MUSPFUncharacterized protein. (192 aa)
MATKTyrosine-protein kinase. (447 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (464 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
NTRK1Tyrosine-protein kinase receptor. (727 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (715 aa)
RPS6KA3Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (741 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (561 aa)
BAXBCL2 associated X, apoptosis regulator. (192 aa)
SORT1Sortilin. (694 aa)
MAPK1Mitogen-activated protein kinase. (333 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
MAPK12Mitogen-activated protein kinase. (287 aa)
MAPK10Mitogen-activated protein kinase. (384 aa)
MAPK11Mitogen-activated protein kinase. (434 aa)
M3XSY8_MUSPFUncharacterized protein. (300 aa)
M3XSY7_MUSPFUncharacterized protein. (242 aa)
NTRK2Neurotrophic receptor tyrosine kinase 2. (477 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
M3XQX1_MUSPFUncharacterized protein. (127 aa)
IRS1Insulin receptor substrate 1. (1428 aa)
MAGED1MAGE family member D1. (820 aa)
GAB1GRB2 associated binding protein 1. (648 aa)
MAPK9Mitogen-activated protein kinase. (398 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
IRAK4Interleukin-1 receptor-associated kinase 4. (460 aa)
MAP2K5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (371 aa)
CALML4Calmodulin like 4. (153 aa)
M3XLW8_MUSPFUncharacterized protein. (183 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
M3YWA8_MUSPFUncharacterized protein. (726 aa)
RPS6KA1Ribosomal protein S6 kinase. (719 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (275 aa)
NGFRNerve growth factor receptor. (429 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (531 aa)
M3YUS4_MUSPFDZF domain-containing protein. (184 aa)
M3YUS3_MUSPFDZF domain-containing protein. (791 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (647 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1398 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
M3YR72_MUSPFUncharacterized protein. (542 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha. (679 aa)
ARSIArylsulfatase family member I. (575 aa)
RHOARas homolog family member A. (193 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (251 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
M3YPM9_MUSPFBZIP domain-containing protein. (351 aa)
PPP1R14BProtein phosphatase 1 regulatory inhibitor subunit 14B. (145 aa)
KIDINS220Kinase D interacting substrate 220. (1376 aa)
M3YNJ8_MUSPFUncharacterized protein. (461 aa)
BADBCL2 associated agonist of cell death. (168 aa)
SH2B1SH2B adaptor protein 1. (757 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
ABL1Tyrosine-protein kinase. (1150 aa)
M3YMK5_MUSPFProtein kinase domain-containing protein. (185 aa)
M3YMK1_MUSPFProtein kinase domain-containing protein. (105 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (399 aa)
NFKBIENFKB inhibitor epsilon. (394 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1265 aa)
SHC4SHC adaptor protein 4. (624 aa)
PRDM4PR domain zinc finger protein 4; May function as a transcription factor involved in cell differentiation. (801 aa)
CALM2Calmodulin 2; Belongs to the calmodulin family. (149 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
RELARELA proto-oncogene, NF-kB subunit. (511 aa)
ARHGDIBRho GDP dissociation inhibitor beta. (200 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (255 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa)
M3YH29_MUSPFUncharacterized protein. (180 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1276 aa)
KRASKRAS proto-oncogene, GTPase. (208 aa)
SHC2Uncharacterized protein. (539 aa)
MAPKAPK2MAPK activated protein kinase 2. (319 aa)
M3YEN4_MUSPFBZIP domain-containing protein. (358 aa)
FOXO3Forkhead box O3. (671 aa)
NFKB1Nuclear factor kappa B subunit 1. (971 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1266 aa)
MAPK8Mitogen-activated protein kinase. (397 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (696 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (375 aa)
SHC3SHC adaptor protein 3. (425 aa)
ZNF274Zinc finger protein 274. (626 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (420 aa)
M3YA76_MUSPFProtein kinase domain-containing protein. (533 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (156 aa)
RPS6KA5Ribosomal protein S6 kinase. (821 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (461 aa)
CALML6Calmodulin like 6. (156 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1343 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (710 aa)
RPS6KA2Ribosomal protein S6 kinase. (733 aa)
RPS6KA6Ribosomal protein S6 kinase. (794 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
SHC1SHC adaptor protein 1. (586 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (270 aa)
M3Z785_MUSPFUncharacterized protein; Belongs to the calmodulin family. (149 aa)
CALML5Calmodulin like 5. (149 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (241 aa)
NTF4Neurotrophin 4; Belongs to the NGF-beta family. (211 aa)
BEX3Brain expressed X-linked 3. (125 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (610 aa)
NFKBIBNFKB inhibitor beta. (354 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
IRAK3Interleukin 1 receptor associated kinase 3. (628 aa)
RAP1BRAP1B, member of RAS oncogene family. (184 aa)
FRS2Fibroblast growth factor receptor substrate 2. (517 aa)
M3Z176_MUSPF14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (221 aa)
CSKTyrosine-protein kinase. (450 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (644 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (580 aa)
PRKCDProtein kinase C. (730 aa)
BCL2BCL2 apoptosis regulator. (207 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
M3YX33_MUSPFUncharacterized protein. (191 aa)
SH2B2SH2B adaptor protein 2. (380 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (448 aa)
NTRK3Tyrosine-protein kinase receptor. (781 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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