STRINGSTRING
M3YH29_MUSPF M3YH29_MUSPF CHRM1 CHRM1 KCNJ2 KCNJ2 CHRM5 CHRM5 SLC18A3 SLC18A3 M3Z6U4_MUSPF M3Z6U4_MUSPF M3Z6N3_MUSPF M3Z6N3_MUSPF ENSMPUP00000018988 ENSMPUP00000018988 ENSMPUP00000018887 ENSMPUP00000018887 CHRM4 CHRM4 GNAI1 GNAI1 PIK3CG PIK3CG CAMK2B CAMK2B ADCY1 ADCY1 CACNA1C CACNA1C M3Z2Z7_MUSPF M3Z2Z7_MUSPF AKT2 AKT2 GNB4 GNB4 PIK3CA PIK3CA ITPR1 ITPR1 CACNA1D CACNA1D GNB3 GNB3 M3YZ57_MUSPF M3YZ57_MUSPF BCL2 BCL2 ACHE ACHE AKT3 AKT3 M3YWA8_MUSPF M3YWA8_MUSPF GNB2 GNB2 CACNA1B CACNA1B ADCY9 ADCY9 ADCY6 ADCY6 PIK3R1 PIK3R1 PRKCA PRKCA M3YT63_MUSPF M3YT63_MUSPF KCNQ4 KCNQ4 ADCY3 ADCY3 PTRHD1 PTRHD1 CAMK2A CAMK2A ARSI ARSI CACNA1F CACNA1F GNG3 GNG3 M3YPM9_MUSPF M3YPM9_MUSPF GNAI2 GNAI2 KCNJ4 KCNJ4 M3YNJ8_MUSPF M3YNJ8_MUSPF PLCB3 PLCB3 CHRNA6 CHRNA6 M3YMU3_MUSPF M3YMU3_MUSPF CHRM3 CHRM3 M3YMK5_MUSPF M3YMK5_MUSPF M3YMK1_MUSPF M3YMK1_MUSPF MAPK3 MAPK3 GNAQ GNAQ M3YLB7_MUSPF M3YLB7_MUSPF PRKCB PRKCB CHRNA3 CHRNA3 CHRNB4 CHRNB4 SLC5A7 SLC5A7 CACNA1S CACNA1S ITPR2 ITPR2 KRAS KRAS FYN FYN PRKCG PRKCG M3YEN4_MUSPF M3YEN4_MUSPF CHAT CHAT FOS FOS PIK3CB PIK3CB KCNJ6 KCNJ6 PLCB2 PLCB2 SRMS SRMS PTK6 PTK6 M3YA76_MUSPF M3YA76_MUSPF KCNQ2 KCNQ2 CHRNA4 CHRNA4 CREB3L4 CREB3L4 PIK3R6 PIK3R6 PIK3R5 PIK3R5 GNB5 GNB5 ADCY2 ADCY2 CHRNB2 CHRNB2 PLCB4 PLCB4 PLCB1 PLCB1 PIK3CD PIK3CD PRKACB PRKACB CSDE1 CSDE1 M3Y2Z6_MUSPF M3Y2Z6_MUSPF M3Z5X6_MUSPF M3Z5X6_MUSPF ADCY4 ADCY4 CREB3L1 CREB3L1 CREB3 CREB3 GNG8 GNG8 KCNQ1 KCNQ1 JAK2 JAK2 CREB5 CREB5 M3Y070_MUSPF M3Y070_MUSPF CREB3L3 CREB3L3 ADCY5 ADCY5 KCNQ5 KCNQ5 KCNJ14 KCNJ14 CHRM2 CHRM2 CREB3L2 CREB3L2 M3XXC7_MUSPF M3XXC7_MUSPF GNA11 GNA11 GNAO1 GNAO1 CAMK2G CAMK2G CACNA1A CACNA1A GNAI3 GNAI3 ADCY7 ADCY7 MAPK1 MAPK1 PRKACA PRKACA ITPR3 ITPR3 AKT1 AKT1 GNGT1 GNGT1 GNG11 GNG11 KCNQ3 KCNQ3 ADCY8 ADCY8 CREB1 CREB1 KCNJ3 KCNJ3 MAP2K1 MAP2K1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
M3YH29_MUSPFUncharacterized protein. (180 aa)
CHRM1Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (460 aa)
KCNJ2Potassium voltage-gated channel subfamily J member 2. (427 aa)
CHRM5Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (532 aa)
SLC18A3Solute carrier family 18 member A3. (517 aa)
M3Z6U4_MUSPFGuanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
M3Z6N3_MUSPFUncharacterized protein. (428 aa)
ENSMPUP00000018988annotation not available (68 aa)
ENSMPUP00000018887annotation not available (68 aa)
CHRM4Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (490 aa)
GNAI1G protein subunit alpha i1. (354 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (610 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1130 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1479 aa)
M3Z2Z7_MUSPFUncharacterized protein. (204 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
GNB4G protein subunit beta 4. (340 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2709 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2217 aa)
GNB3G protein subunit beta 3. (344 aa)
M3YZ57_MUSPFUncharacterized protein. (168 aa)
BCL2BCL2 apoptosis regulator. (207 aa)
ACHECarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (612 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
M3YWA8_MUSPFUncharacterized protein. (726 aa)
GNB2G protein subunit beta 2. (340 aa)
CACNA1BCalcium voltage-gated channel subunit alpha1 B. (1971 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (688 aa)
M3YT63_MUSPFUncharacterized protein. (501 aa)
KCNQ4Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family. (609 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha. (679 aa)
ARSIArylsulfatase family member I. (575 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1986 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (76 aa)
M3YPM9_MUSPFBZIP domain-containing protein. (351 aa)
GNAI2G protein subunit alpha i2. (355 aa)
KCNJ4Potassium voltage-gated channel subfamily J member 4. (428 aa)
M3YNJ8_MUSPFUncharacterized protein. (461 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1233 aa)
CHRNA6Cholinergic receptor nicotinic alpha 6 subunit. (494 aa)
M3YMU3_MUSPFMIR domain-containing protein. (78 aa)
CHRM3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (622 aa)
M3YMK5_MUSPFProtein kinase domain-containing protein. (185 aa)
M3YMK1_MUSPFProtein kinase domain-containing protein. (105 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (399 aa)
GNAQG protein subunit alpha q. (301 aa)
M3YLB7_MUSPFUncharacterized protein. (417 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (577 aa)
CHRNA3Cholinergic receptor nicotinic alpha 3 subunit. (438 aa)
CHRNB4Cholinergic receptor nicotinic beta 4 subunit. (494 aa)
SLC5A7Solute carrier family 5 member 7; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (579 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1795 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
KRASKRAS proto-oncogene, GTPase. (208 aa)
FYNTyrosine-protein kinase. (537 aa)
PRKCGNon-specific serine/threonine protein kinase. (569 aa)
M3YEN4_MUSPFBZIP domain-containing protein. (358 aa)
CHATCholine O-acetyltransferase; Belongs to the carnitine/choline acetyltransferase family. (748 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (446 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (423 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1187 aa)
SRMSTyrosine-protein kinase. (507 aa)
PTK6Tyrosine-protein kinase. (444 aa)
M3YA76_MUSPFProtein kinase domain-containing protein. (533 aa)
KCNQ2Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family. (770 aa)
CHRNA4Neuronal acetylcholine receptor subunit alpha-4; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions. (544 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (386 aa)
PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (755 aa)
PIK3R5Phosphoinositide-3-kinase regulatory subunit 5. (778 aa)
GNB5G protein subunit beta 5. (301 aa)
ADCY2Adenylate cyclase 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (880 aa)
CHRNB2Cholinergic receptor nicotinic beta 2 subunit. (479 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1096 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
CSDE1Cold shock domain containing E1. (784 aa)
M3Y2Z6_MUSPFUncharacterized protein. (189 aa)
M3Z5X6_MUSPFGuanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1105 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (520 aa)
CREB3cAMP responsive element binding protein 3. (353 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (76 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (590 aa)
JAK2Tyrosine-protein kinase. (1130 aa)
CREB5cAMP responsive element binding protein 5. (275 aa)
M3Y070_MUSPFGuanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (473 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1018 aa)
KCNQ5Potassium voltage-gated channel subfamily Q member 5. (803 aa)
KCNJ14Potassium voltage-gated channel subfamily J member 14. (433 aa)
CHRM2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (496 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
M3XXC7_MUSPFUncharacterized protein. (93 aa)
GNA11G protein subunit alpha 11. (334 aa)
GNAO1G protein subunit alpha o1. (354 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (561 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2496 aa)
GNAI3G protein subunit alpha i3. (354 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
MAPK1Mitogen-activated protein kinase. (333 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2609 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
KCNQ3Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family. (743 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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