STRINGSTRING
SORBS1 SORBS1 M3Z098_MUSPF M3Z098_MUSPF M3Z099_MUSPF M3Z099_MUSPF RAF1 RAF1 PIK3CA PIK3CA PPP1R3C PPP1R3C PTPN1 PTPN1 AKT2 AKT2 PRKAR1B PRKAR1B REM1 REM1 PPP1CB PPP1CB GCK GCK PRKAR2B PRKAR2B M3Z5X1_MUSPF M3Z5X1_MUSPF M3Z5X4_MUSPF M3Z5X4_MUSPF M3Z6U6_MUSPF M3Z6U6_MUSPF CALML5 CALML5 M3Z785_MUSPF M3Z785_MUSPF SOCS4 SOCS4 M3Z826_MUSPF M3Z826_MUSPF SOCS3 SOCS3 PPP1R3B PPP1R3B M3Z8B6_MUSPF M3Z8B6_MUSPF SOCS1 SOCS1 PPP1R3D PPP1R3D SREBF1 SREBF1 GYS2 GYS2 CALML4 CALML4 MAP2K1 MAP2K1 MAPK9 MAPK9 PRKAB2 PRKAB2 NOSTRIN NOSTRIN G6PC2 G6PC2 IRS1 IRS1 M3XSH0_MUSPF M3XSH0_MUSPF AKT1 AKT1 PPP1CC PPP1CC INPP5A INPP5A MAPK10 MAPK10 PRKAB1 PRKAB1 PHKA2 PHKA2 PHKB PHKB PRKACA PRKACA M3XVG3_MUSPF M3XVG3_MUSPF M3XVG8_MUSPF M3XVG8_MUSPF M3XVI9_MUSPF M3XVI9_MUSPF MAPK1 MAPK1 GYS1 GYS1 BRAF BRAF ACACB ACACB SORBS3 SORBS3 CRKL CRKL PPP1CA PPP1CA RPS6KB2 RPS6KB2 IRS4 IRS4 HK1 HK1 HKDC1 HKDC1 M3XZF1_MUSPF M3XZF1_MUSPF M3Y027_MUSPF M3Y027_MUSPF SOS2 SOS2 M3Y1G8_MUSPF M3Y1G8_MUSPF PYGL PYGL CALM3 CALM3 RRAD RRAD PTPRS PTPRS PHKA1 PHKA1 CBL CBL PKLR PKLR INS INS M3Y2Z6_MUSPF M3Y2Z6_MUSPF CSDE1 CSDE1 PRKACB PRKACB SHC1 SHC1 PCK2 PCK2 PIK3CD PIK3CD FBP2 FBP2 PCK1 PCK1 FBP1 FBP1 PPP1R3E PPP1R3E TRIP10 TRIP10 MKNK2 MKNK2 ELK3 ELK3 SYCP2 SYCP2 PRKAA2 PRKAA2 M3Y7F8_MUSPF M3Y7F8_MUSPF SOCS2 SOCS2 TMEM145 TMEM145 PPP1R3A PPP1R3A BMT2 BMT2 PRKCZ PRKCZ CALML6 CALML6 EFCAB13 EFCAB13 CALM1 CALM1 LIPE LIPE HK2 HK2 GSK3B GSK3B INSR INSR SHC3 SHC3 CRYGN CRYGN RHEB RHEB PRKAG2 PRKAG2 GEM GEM PIK3CB PIK3CB MAPK8 MAPK8 G6PC3 G6PC3 M3YEF8_MUSPF M3YEF8_MUSPF CBLB CBLB EIF4EBP1 EIF4EBP1 G6PC G6PC SHC2 SHC2 INPPL1 INPPL1 KRAS KRAS SLC2A4 SLC2A4 SOS1 SOS1 M3YH29_MUSPF M3YH29_MUSPF M3YIA6_MUSPF M3YIA6_MUSPF FASN FASN SORBS2 SORBS2 FLOT1 FLOT1 RPTOR RPTOR RHOQ RHOQ CALM2 CALM2 PHKG2 PHKG2 SHC4 SHC4 HK3 HK3 TSC1 TSC1 EIF4E1B EIF4E1B RAPGEF1 RAPGEF1 MAPK3 MAPK3 IKBKB IKBKB PYGM PYGM MKNK1 MKNK1 BAD BAD M3YNJ8_MUSPF M3YNJ8_MUSPF PPP1R14B PPP1R14B PDE3B PDE3B ARAF ARAF ELK1 ELK1 EXOC7 EXOC7 PTPRF PTPRF CRYBB3 CRYBB3 KIAA1671 KIAA1671 CRK CRK GRB2 GRB2 PPP1R3F PPP1R3F FLOT2 FLOT2 PRKAR2A PRKAR2A PRKAR1A PRKAR1A RHEBL1 RHEBL1 PRKAG1 PRKAG1 PIK3R1 PIK3R1 PRKAA1 PRKAA1 PTPRD PTPRD ACACA ACACA RPS6KB1 RPS6KB1 EFCAB3 EFCAB3 M3YUS7_MUSPF M3YUS7_MUSPF M3YUT2_MUSPF M3YUT2_MUSPF PDPK1 PDPK1 TSC2 TSC2 PYGB PYGB M3YW64_MUSPF M3YW64_MUSPF M3YWA8_MUSPF M3YWA8_MUSPF AKT3 AKT3 SH2B2 SH2B2 ALKBH4 ALKBH4 MYO9B MYO9B M3YX47_MUSPF M3YX47_MUSPF BUD23 BUD23 PHKG1 PHKG1 SREBF2 SREBF2 MTOR MTOR PRKAG3 PRKAG3 PPARGC1A PPARGC1A PRKCI PRKCI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SORBS1Sorbin and SH3 domain containing 1. (1169 aa)
M3Z098_MUSPFRho-GAP domain-containing protein. (479 aa)
M3Z099_MUSPFUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2005 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (644 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PPP1R3CProtein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. (316 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (424 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (415 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
GCKPhosphotransferase. (473 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (439 aa)
M3Z5X1_MUSPFUncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (217 aa)
M3Z5X4_MUSPFUncharacterized protein. (338 aa)
M3Z6U6_MUSPFUncharacterized protein. (457 aa)
CALML5Calmodulin like 5. (149 aa)
M3Z785_MUSPFUncharacterized protein; Belongs to the calmodulin family. (149 aa)
SOCS4Suppressor of cytokine signaling 4. (441 aa)
M3Z826_MUSPF40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (243 aa)
SOCS3Suppressor of cytokine signaling 3. (225 aa)
PPP1R3BProtein phosphatase 1 regulatory subunit. (284 aa)
M3Z8B6_MUSPFUncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (216 aa)
SOCS1Suppressor of cytokine signaling 1. (216 aa)
PPP1R3DProtein phosphatase 1 regulatory subunit. (299 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1147 aa)
GYS2Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (703 aa)
CALML4Calmodulin like 4. (153 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
MAPK9Mitogen-activated protein kinase. (398 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (296 aa)
NOSTRINNitric oxide synthase trafficking. (496 aa)
G6PC2Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (356 aa)
IRS1Insulin receptor substrate 1. (1428 aa)
M3XSH0_MUSPFUncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (219 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
INPP5AInositol polyphosphate-5-phosphatase A. (364 aa)
MAPK10Mitogen-activated protein kinase. (384 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
PHKA2Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1238 aa)
PHKBPhosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (1086 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
M3XVG3_MUSPFUncharacterized protein. (80 aa)
M3XVG8_MUSPFUncharacterized protein. (1073 aa)
M3XVI9_MUSPFUncharacterized protein. (146 aa)
MAPK1Mitogen-activated protein kinase. (333 aa)
GYS1Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (644 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (715 aa)
ACACBAcetyl-CoA carboxylase beta. (2456 aa)
SORBS3Sorbin and SH3 domain containing 3. (732 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (479 aa)
IRS4Insulin receptor substrate 4. (1259 aa)
HK1Hexokinase 1. (917 aa)
HKDC1Hexokinase domain containing 1. (704 aa)
M3XZF1_MUSPFPhosphotransferase. (133 aa)
M3Y027_MUSPFProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1281 aa)
M3Y1G8_MUSPFUncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (245 aa)
PYGLAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (858 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (151 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1905 aa)
PHKA1Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1181 aa)
CBLCbl proto-oncogene. (913 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (574 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (109 aa)
M3Y2Z6_MUSPFUncharacterized protein. (189 aa)
CSDE1Cold shock domain containing E1. (784 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
SHC1SHC adaptor protein 1. (586 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (620 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
FBP2Fructose-bisphosphatase 2; Belongs to the FBPase class 1 family. (339 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
FBP1Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (338 aa)
PPP1R3EProtein phosphatase 1 regulatory subunit 3E. (279 aa)
TRIP10Thyroid hormone receptor interactor 10. (565 aa)
MKNK2MAPK interacting serine/threonine kinase 2; Belongs to the protein kinase superfamily. (464 aa)
ELK3ETS transcription factor ELK3. (418 aa)
SYCP2Synaptonemal complex protein 2. (1464 aa)
PRKAA2Non-specific serine/threonine protein kinase. (524 aa)
M3Y7F8_MUSPFEF-hand domain-containing protein; Belongs to the calmodulin family. (119 aa)
SOCS2Suppressor of cytokine signaling 2. (198 aa)
TMEM145Transmembrane protein 145. (703 aa)
PPP1R3AProtein phosphatase 1 regulatory subunit 3A. (1117 aa)
BMT2S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] (405 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (582 aa)
CALML6Calmodulin like 6. (156 aa)
EFCAB13EF-hand calcium binding domain 13. (792 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (156 aa)
LIPELipase E, hormone sensitive type. (797 aa)
HK2Hexokinase 2. (917 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (420 aa)
INSRTyrosine-protein kinase receptor. (1352 aa)
SHC3SHC adaptor protein 3. (425 aa)
CRYGNCrystallin gamma N; Belongs to the beta/gamma-crystallin family. (183 aa)
RHEBRas homolog, mTORC1 binding. (179 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (529 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (296 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
MAPK8Mitogen-activated protein kinase. (397 aa)
G6PC3Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa)
M3YEF8_MUSPFFOXO-TAD domain-containing protein. (399 aa)
CBLBCbl proto-oncogene B. (983 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E binding protein 1. (118 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
SHC2Uncharacterized protein. (539 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1264 aa)
KRASKRAS proto-oncogene, GTPase. (208 aa)
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1276 aa)
M3YH29_MUSPFUncharacterized protein. (180 aa)
M3YIA6_MUSPFUncharacterized protein. (333 aa)
FASNFatty acid synthase. (2309 aa)
SORBS2Sorbin and SH3 domain containing 2. (1352 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (405 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1244 aa)
RHOQRas homolog family member Q. (205 aa)
CALM2Calmodulin 2; Belongs to the calmodulin family. (149 aa)
PHKG2Phosphorylase kinase catalytic subunit gamma 2; Belongs to the protein kinase superfamily. (406 aa)
SHC4SHC adaptor protein 4. (624 aa)
HK3Hexokinase 3. (924 aa)
TSC1TSC complex subunit 1. (1165 aa)
EIF4E1BEukaryotic translation initiation factor 4E family member 1B; Belongs to the eukaryotic initiation factor 4E family. (263 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1265 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (399 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
PYGMAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (842 aa)
MKNK1MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (415 aa)
BADBCL2 associated agonist of cell death. (168 aa)
M3YNJ8_MUSPFUncharacterized protein. (461 aa)
PPP1R14BProtein phosphatase 1 regulatory inhibitor subunit 14B. (145 aa)
PDE3BPhosphodiesterase. (889 aa)
ARAFV-raf murine sarcoma 3611 viral oncoprotein-like protein. (606 aa)
ELK1ETS transcription factor ELK1. (435 aa)
EXOC7Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (760 aa)
PTPRFProtein tyrosine phosphatase receptor type F. (1906 aa)
CRYBB3Crystallin beta B3; Belongs to the beta/gamma-crystallin family. (211 aa)
KIAA1671KIAA1671. (1838 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
PPP1R3FProtein phosphatase 1 regulatory subunit 3F. (813 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)
PRKAR2AProtein kinase cAMP-dependent type II regulatory subunit alpha. (305 aa)
PRKAR1AProtein kinase cAMP-dependent type I regulatory subunit alpha. (422 aa)
RHEBL1RHEB like 1. (177 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (329 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
PRKAA1Non-specific serine/threonine protein kinase. (517 aa)
PTPRDProtein tyrosine phosphatase receptor type D. (1912 aa)
ACACAAcetyl-CoA carboxylase alpha. (2383 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
EFCAB3EF-hand calcium binding domain 3. (436 aa)
M3YUS7_MUSPFUncharacterized protein. (74 aa)
M3YUT2_MUSPFUncharacterized protein. (90 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (531 aa)
TSC2TSC complex subunit 2. (1906 aa)
PYGBAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (864 aa)
M3YW64_MUSPFUncharacterized protein. (513 aa)
M3YWA8_MUSPFUncharacterized protein. (726 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
SH2B2SH2B adaptor protein 2. (380 aa)
ALKBH4AlkB homolog 4, lysine demethylase. (308 aa)
MYO9BMyosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2161 aa)
M3YX47_MUSPFUncharacterized protein. (94 aa)
BUD23BUD23 rRNA methyltransferase and ribosome maturation factor. (264 aa)
PHKG1Phosphorylase kinase catalytic subunit gamma 1; Belongs to the protein kinase superfamily. (387 aa)
SREBF2Sterol regulatory element binding transcription factor 2. (1104 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2552 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (488 aa)
PPARGC1APPARG coactivator 1 alpha. (796 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (638 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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