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PLCB1 PLCB1 CREB1 CREB1 ATP1B1 ATP1B1 CANX CANX LRP2 LRP2 GPX5 GPX5 GPX6 GPX6 ADCY8 ADCY8 ATP1B4 ATP1B4 TG TG TTF2 TTF2 ATP1A1 ATP1A1 TSHB TSHB M3XRM2_MUSPF M3XRM2_MUSPF M3XRM4_MUSPF M3XRM4_MUSPF M3XRN2_MUSPF M3XRN2_MUSPF ITPR3 ITPR3 PRKACA PRKACA ADCY7 ADCY7 SERPINA9 SERPINA9 GNA11 GNA11 CREB3L2 CREB3L2 M3XZ71_MUSPF M3XZ71_MUSPF ADCY5 ADCY5 CREB3L3 CREB3L3 CREB5 CREB5 SERPINA7 SERPINA7 CREB3 CREB3 CREB3L1 CREB3L1 ADCY4 ADCY4 PRKACB PRKACB M3Y334_MUSPF M3Y334_MUSPF M3Y692_MUSPF M3Y692_MUSPF TTR TTR ADCY2 ADCY2 M3Y7G0_MUSPF M3Y7G0_MUSPF GPX8 GPX8 CREB3L4 CREB3L4 PLCB2 PLCB2 TSHR TSHR ATP1B2 ATP1B2 ALB ALB PAX8 PAX8 CGA CGA M3YEN4_MUSPF M3YEN4_MUSPF PRKCG PRKCG GSR GSR ATF6B ATF6B ITPR2 ITPR2 IYD IYD ASGR1 ASGR1 ASGR2 ASGR2 DUOX2 DUOX2 DUOXA2 DUOXA2 M3YHJ5_MUSPF M3YHJ5_MUSPF DUOX1 DUOX1 M3YJ32_MUSPF M3YJ32_MUSPF HSP90B1 HSP90B1 ATP1B3 ATP1B3 PRKCB PRKCB M3YLC0_MUSPF M3YLC0_MUSPF TTF1 TTF1 GNAQ GNAQ M3YMU3_MUSPF M3YMU3_MUSPF M3YN22_MUSPF M3YN22_MUSPF PLCB3 PLCB3 ATP1A2 ATP1A2 M3YPM9_MUSPF M3YPM9_MUSPF GPX3 GPX3 GPX1 GPX1 HSPA5 HSPA5 ATP1A4 ATP1A4 ATF2 ATF2 PTRHD1 PTRHD1 ADCY3 ADCY3 PRKCA PRKCA ADCY6 ADCY6 ADCY9 ADCY9 SLC5A5 SLC5A5 ITPR1 ITPR1 ADCY1 ADCY1 SLC26A4 SLC26A4 PLCB4 PLCB4 PDIA4 PDIA4 GPX7 GPX7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1096 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (300 aa)
CANXCalnexin. (484 aa)
LRP2LDL receptor related protein 2. (4699 aa)
GPX5Glutathione peroxidase; Belongs to the glutathione peroxidase family. (221 aa)
GPX6Glutathione peroxidase; Belongs to the glutathione peroxidase family. (153 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (363 aa)
TGThyroglobulin. (2763 aa)
TTF2Uncharacterized protein. (1156 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1021 aa)
TSHBThyroid stimulating hormone subunit beta. (138 aa)
M3XRM2_MUSPFUncharacterized protein. (74 aa)
M3XRM4_MUSPFUncharacterized protein. (239 aa)
M3XRN2_MUSPFUncharacterized protein. (90 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2609 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
SERPINA9Serpin family A member 9; Belongs to the serpin family. (463 aa)
GNA11G protein subunit alpha 11. (334 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
M3XZ71_MUSPFFXYD domain-containing ion transport regulator; Belongs to the FXYD family. (64 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1018 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (473 aa)
CREB5cAMP responsive element binding protein 5. (275 aa)
SERPINA7Serpin family A member 7; Belongs to the serpin family. (422 aa)
CREB3cAMP responsive element binding protein 3. (353 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (520 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1105 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
M3Y334_MUSPFUncharacterized protein. (312 aa)
M3Y692_MUSPFUncharacterized protein. (362 aa)
TTRTransthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (147 aa)
ADCY2Adenylate cyclase 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (880 aa)
M3Y7G0_MUSPFSodium/potassium-transporting ATPase subunit alpha. (1037 aa)
GPX8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (171 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (386 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1187 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (784 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
ALBAlbumin. (608 aa)
PAX8Paired box 8. (462 aa)
CGAGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (120 aa)
M3YEN4_MUSPFBZIP domain-containing protein. (358 aa)
PRKCGNon-specific serine/threonine protein kinase. (569 aa)
GSRGlutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (481 aa)
ATF6BActivating transcription factor 6 beta. (707 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
IYDIodotyrosine deiodinase. (323 aa)
ASGR1Asialoglycoprotein receptor 1. (290 aa)
ASGR2Asialoglycoprotein receptor 2. (301 aa)
DUOX2Dual oxidase 2. (1307 aa)
DUOXA2Dual oxidase maturation factor 2. (325 aa)
M3YHJ5_MUSPFUncharacterized protein. (133 aa)
DUOX1Dual oxidase 1. (1450 aa)
M3YJ32_MUSPFEGF-like domain-containing protein. (872 aa)
HSP90B1Heat shock protein 90 beta family member 1. (803 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (253 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (577 aa)
M3YLC0_MUSPFEGF-like domain-containing protein. (710 aa)
TTF1Transcription termination factor 1. (761 aa)
GNAQG protein subunit alpha q. (301 aa)
M3YMU3_MUSPFMIR domain-containing protein. (78 aa)
M3YN22_MUSPFEGF-like domain-containing protein. (930 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1233 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1023 aa)
M3YPM9_MUSPFBZIP domain-containing protein. (351 aa)
GPX3Glutathione peroxidase; Belongs to the glutathione peroxidase family. (226 aa)
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (154 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1031 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (688 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
SLC5A5Solute carrier family 5 member 5; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (642 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2709 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1130 aa)
SLC26A4Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (780 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
PDIA4Protein disulfide-isomerase A4. (645 aa)
GPX7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (261 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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