STRINGSTRING
CREB3L1 CREB3L1 CREB3 CREB3 M3Y1M3_MUSPF M3Y1M3_MUSPF CREB5 CREB5 CREB3L3 CREB3L3 AGT AGT ADCY5 ADCY5 CREB3L2 CREB3L2 PBX1 PBX1 M3XXC7_MUSPF M3XXC7_MUSPF GNA11 GNA11 ADCY7 ADCY7 KCNK2 KCNK2 PRKACA PRKACA NR0B1 NR0B1 ITPR3 ITPR3 ORAI1 ORAI1 M3XQV0_MUSPF M3XQV0_MUSPF SCARB1 SCARB1 ADCY8 ADCY8 M3XPW1_MUSPF M3XPW1_MUSPF CREB1 CREB1 KCNA4 KCNA4 KCNA3 KCNA3 KCNA2 KCNA2 KCNA10 KCNA10 MC2R MC2R AGTR1 AGTR1 KCNA5 KCNA5 KCNA1 KCNA1 ADCY1 ADCY1 CACNA1C CACNA1C M3Z2Z7_MUSPF M3Z2Z7_MUSPF CYP11A1 CYP11A1 NCEH1 NCEH1 ITPR1 ITPR1 CYP17A1 CYP17A1 CACNA1D CACNA1D M3YZ57_MUSPF M3YZ57_MUSPF CACNA1H CACNA1H PDE8A PDE8A CACNA1G CACNA1G ADCY9 ADCY9 ADCY6 ADCY6 POMC POMC ADCY3 ADCY3 PTRHD1 PTRHD1 ATF2 ATF2 NR5A1 NR5A1 CACNA1F CACNA1F CACNA1I CACNA1I M3YPM9_MUSPF M3YPM9_MUSPF PLCB3 PLCB3 M3YMU3_MUSPF M3YMU3_MUSPF GNAQ GNAQ CACNA1S CACNA1S ITPR2 ITPR2 ATF6B ATF6B STAR STAR M3YEN4_MUSPF M3YEN4_MUSPF PLCB2 PLCB2 KCNK3 KCNK3 CREB3L4 CREB3L4 NR4A1 NR4A1 ADCY2 ADCY2 M3Y692_MUSPF M3Y692_MUSPF PLCB4 PLCB4 PLCB1 PLCB1 SP1 SP1 PRKACB PRKACB LDLR LDLR ADCY4 ADCY4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CREB3L1cAMP responsive element binding protein 3 like 1. (520 aa)
CREB3cAMP responsive element binding protein 3. (353 aa)
M3Y1M3_MUSPFPhosphodiesterase. (782 aa)
CREB5cAMP responsive element binding protein 5. (275 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (473 aa)
AGTAngiotensinogen; Belongs to the serpin family. (477 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1018 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
PBX1PBX homeobox 1. (430 aa)
M3XXC7_MUSPFUncharacterized protein. (93 aa)
GNA11G protein subunit alpha 11. (334 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (422 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1. (474 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2609 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (288 aa)
M3XQV0_MUSPF3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (377 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
M3XPW1_MUSPFUncharacterized protein. (140 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
KCNA4Potassium voltage-gated channel subfamily A member 4; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium- selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, and possibly other family members as well [...] (654 aa)
KCNA3Potassium voltage-gated channel subfamily A member 3; Belongs to the potassium channel family. (439 aa)
KCNA2Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family. (499 aa)
KCNA10Potassium voltage-gated channel subfamily A member 10; Belongs to the potassium channel family. (511 aa)
MC2RMelanocortin 2 receptor. (297 aa)
AGTR1Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (359 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium- selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane (By similarity). Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, and possibly other family [...] (601 aa)
KCNA1Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (495 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1130 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1479 aa)
M3Z2Z7_MUSPFUncharacterized protein. (204 aa)
CYP11A1Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (520 aa)
NCEH1Neutral cholesterol ester hydrolase 1. (408 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2709 aa)
CYP17A1Cytochrome P450 family 17 subfamily A member 1; Belongs to the cytochrome P450 family. (508 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2217 aa)
M3YZ57_MUSPFUncharacterized protein. (168 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2143 aa)
PDE8APhosphodiesterase. (773 aa)
CACNA1GCalcium voltage-gated channel subunit alpha1 G. (2177 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
POMCProopiomelanocortin. (265 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
NR5A1Nuclear receptor subfamily 5 group A member 1. (384 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1986 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2024 aa)
M3YPM9_MUSPFBZIP domain-containing protein. (351 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1233 aa)
M3YMU3_MUSPFMIR domain-containing protein. (78 aa)
GNAQG protein subunit alpha q. (301 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1795 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
ATF6BActivating transcription factor 6 beta. (707 aa)
STARSteroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa)
M3YEN4_MUSPFBZIP domain-containing protein. (358 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1187 aa)
KCNK3Potassium channel subfamily K member. (357 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (386 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (598 aa)
ADCY2Adenylate cyclase 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (880 aa)
M3Y692_MUSPFUncharacterized protein. (362 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1096 aa)
SP1Sp1 transcription factor. (787 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
LDLRLow density lipoprotein receptor. (856 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1105 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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