(24 nodes) Proximal tubule bicarbonate reclamation network (Mustela putorius)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

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Your Input:
	PCK2	Phosphoenolpyruvate carboxykinase 2, mitochondrial. (620 aa)
	ATP1B1	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (300 aa)
	ATP1B4	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (363 aa)
	GLS2	Glutaminase 2. (602 aa)
	ATP1A1	Sodium/potassium-transporting ATPase subunit alpha. (1021 aa)
	M3XZ71_MUSPF	FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (64 aa)
	MINDY4	MINDY lysine 48 deubiquitinase 4. (764 aa)
	AQP1	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
	MDH1	Malate dehydrogenase. (334 aa)
	SLC9A5	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (899 aa)
	PCK1	Phosphoenolpyruvate carboxykinase 1. (622 aa)
	M3Y7G0_MUSPF	Sodium/potassium-transporting ATPase subunit alpha. (1037 aa)
	M3YC07_MUSPF	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (490 aa)
	ATP1B2	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
	SLC4A4	Anion exchange protein. (1086 aa)
	SLC9A3	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (704 aa)
	CA2	Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family. (260 aa)
	SLC25A10	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (244 aa)
	ATP1B3	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (253 aa)
	GLS	Glutaminase. (541 aa)
	ATP1A2	Sodium/potassium-transporting ATPase subunit alpha. (1023 aa)
	SLC38A3	Solute carrier family 38 member 3. (504 aa)
	ATP1A4	Sodium/potassium-transporting ATPase subunit alpha. (1031 aa)
	CA4	Carbonic anhydrase 4; Belongs to the alpha-carbonic anhydrase family. (311 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP1A1	ATP1A2	ENSMPUP00000001621	ENSMPUP00000013095	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.888
ATP1A1	ATP1A4	ENSMPUP00000001621	ENSMPUP00000013798	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.951
ATP1A1	ATP1B1	ENSMPUP00000001621	ENSMPUP00000000502	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.999
ATP1A1	ATP1B2	ENSMPUP00000001621	ENSMPUP00000008954	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.984
ATP1A1	ATP1B3	ENSMPUP00000001621	ENSMPUP00000012069	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.988
ATP1A1	ATP1B4	ENSMPUP00000001621	ENSMPUP00000001417	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.981
ATP1A1	M3XZ71_MUSPF	ENSMPUP00000001621	ENSMPUP00000004372	Sodium/potassium-transporting ATPase subunit alpha.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.999
ATP1A1	M3Y7G0_MUSPF	ENSMPUP00000001621	ENSMPUP00000007267	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.888
ATP1A2	ATP1A1	ENSMPUP00000013095	ENSMPUP00000001621	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.888
ATP1A2	ATP1A4	ENSMPUP00000013095	ENSMPUP00000013798	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.887
ATP1A2	ATP1B1	ENSMPUP00000013095	ENSMPUP00000000502	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.976
ATP1A2	ATP1B2	ENSMPUP00000013095	ENSMPUP00000008954	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.949
ATP1A2	ATP1B3	ENSMPUP00000013095	ENSMPUP00000012069	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.947
ATP1A2	ATP1B4	ENSMPUP00000013095	ENSMPUP00000001417	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.946
ATP1A2	M3XZ71_MUSPF	ENSMPUP00000013095	ENSMPUP00000004372	Sodium/potassium-transporting ATPase subunit alpha.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.953
ATP1A2	M3Y7G0_MUSPF	ENSMPUP00000013095	ENSMPUP00000007267	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.876
ATP1A4	ATP1A1	ENSMPUP00000013798	ENSMPUP00000001621	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.951
ATP1A4	ATP1A2	ENSMPUP00000013798	ENSMPUP00000013095	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.887
ATP1A4	ATP1B1	ENSMPUP00000013798	ENSMPUP00000000502	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.989
ATP1A4	ATP1B2	ENSMPUP00000013798	ENSMPUP00000008954	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.978