STRINGSTRING
NPY NPY M3YPM9_MUSPF M3YPM9_MUSPF ARAF ARAF GNAI2 GNAI2 MAOB MAOB M3YMK5_MUSPF M3YMK5_MUSPF M3YMK1_MUSPF M3YMK1_MUSPF MAOA MAOA MACROH2A2 MACROH2A2 SLC18A1 SLC18A1 SLC29A3 SLC29A3 GRIN2D GRIN2D CREB3L2 CREB3L2 HDAC4 HDAC4 CALML4 CALML4 MAP2K1 MAP2K1 HDAC7 HDAC7 CREB1 CREB1 HAT1 HAT1 M3XPS3_MUSPF M3XPS3_MUSPF GNG11 GNG11 GNGT1 GNGT1 NTRK2 NTRK2 PPP1CC PPP1CC HDAC10 HDAC10 ADORA2A ADORA2A SLC29A2 SLC29A2 PRKACA PRKACA MAPK1 MAPK1 GNAI3 GNAI3 SLC18A2 SLC18A2 BRAF BRAF GNAO1 GNAO1 PPP1CA PPP1CA DRD2 DRD2 CSDE1 CSDE1 M3Y2Z6_MUSPF M3Y2Z6_MUSPF M3Z5X6_MUSPF M3Z5X6_MUSPF CREB3L1 CREB3L1 TH TH H2BC18 H2BC18 CREB3 CREB3 M3Y1V5_MUSPF M3Y1V5_MUSPF CALM3 CALM3 GNG8 GNG8 SOS2 SOS2 ADCY5 ADCY5 M3YQU9_MUSPF M3YQU9_MUSPF CREB3L3 CREB3L3 M3Y070_MUSPF M3Y070_MUSPF CREB5 CREB5 M3YEN4_MUSPF M3YEN4_MUSPF PDYN PDYN HDAC5 HDAC5 H2AZ1 H2AZ1 GRIN3B GRIN3B H6VYP2_MUSPF H6VYP2_MUSPF LOC106004309 LOC106004309 M3YBE3_MUSPF M3YBE3_MUSPF H2BC5 H2BC5 M3YB62_MUSPF M3YB62_MUSPF SHC3 SHC3 HDAC3 HDAC3 CALM1 CALM1 CALML6 CALML6 CREB3L4 CREB3L4 SLC6A3 SLC6A3 GNB5 GNB5 GRIN3A GRIN3A M3Y692_MUSPF M3Y692_MUSPF SHC1 SHC1 FOSB FOSB PRKACB PRKACB MAPK3 MAPK3 SLC29A1 SLC29A1 CAMKK1 CAMKK1 SHC4 SHC4 CALM2 CALM2 GRIN2B GRIN2B M3YJI6_MUSPF M3YJI6_MUSPF BDNF BDNF M3YH29_MUSPF M3YH29_MUSPF SOS1 SOS1 ATF6B ATF6B KRAS KRAS HDAC2 HDAC2 ADORA2B ADORA2B PKIA PKIA ZC2HC1A ZC2HC1A MACROH2A1 MACROH2A1 SHC2 SHC2 ENSMPUP00000019801 ENSMPUP00000019801 M3Z785_MUSPF M3Z785_MUSPF CALML5 CALML5 M3Z750_MUSPF M3Z750_MUSPF M3Z6U4_MUSPF M3Z6U4_MUSPF LOC101680718 LOC101680718 M3Z6J8_MUSPF M3Z6J8_MUSPF DRD1 DRD1 M3Z687_MUSPF M3Z687_MUSPF ENSMPUP00000018988 ENSMPUP00000018988 ENSMPUP00000018887 ENSMPUP00000018887 M3Z5A7_MUSPF M3Z5A7_MUSPF M3Z4T9_MUSPF M3Z4T9_MUSPF CRH CRH H2AC1 H2AC1 H2BC1 H2BC1 ENSMPUP00000018499 ENSMPUP00000018499 H1-6 H1-6 M3Z4I5_MUSPF M3Z4I5_MUSPF M3Z4I4_MUSPF M3Z4I4_MUSPF M3Z4I3_MUSPF M3Z4I3_MUSPF M3Z4I2_MUSPF M3Z4I2_MUSPF G9L0N9_MUSPF G9L0N9_MUSPF HIST3H2BB HIST3H2BB H2AW H2AW H3-4 H3-4 M3Z3Z5_MUSPF M3Z3Z5_MUSPF H2BC21 H2BC21 H2AC20 H2AC20 H2AC21 H2AC21 GNAI1 GNAI1 H2AZ2 H2AZ2 DDC DDC PPP1CB PPP1CB HDAC11 HDAC11 GNB4 GNB4 RAF1 RAF1 GNB3 GNB3 GNB2 GNB2 HDAC1 HDAC1 GRIN1 GRIN1 PPP1R1B PPP1R1B M3YTL0_MUSPF M3YTL0_MUSPF GRIN2A GRIN2A M3YSI0_MUSPF M3YSI0_MUSPF GRIN2C GRIN2C ATF2 ATF2 HDAC9 HDAC9 GRB2 GRB2 ENSMPUP00000013708 ENSMPUP00000013708 GNG3 GNG3 HDAC6 HDAC6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NPYNeuropeptide Y. (97 aa)
M3YPM9_MUSPFBZIP domain-containing protein. (351 aa)
ARAFV-raf murine sarcoma 3611 viral oncoprotein-like protein. (606 aa)
GNAI2G protein subunit alpha i2. (355 aa)
MAOBAmine oxidase. (521 aa)
M3YMK5_MUSPFProtein kinase domain-containing protein. (185 aa)
M3YMK1_MUSPFProtein kinase domain-containing protein. (105 aa)
MAOAAmine oxidase. (518 aa)
MACROH2A2Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
SLC18A1Solute carrier family 18 member A1. (524 aa)
SLC29A3Solute carrier family 29 member 3. (472 aa)
GRIN2DGlutamate ionotropic receptor NMDA type subunit 2D; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (738 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1083 aa)
CALML4Calmodulin like 4. (153 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (991 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
HAT1Histone acetyltransferase 1. (337 aa)
M3XPS3_MUSPFHistone H2B; Belongs to the histone H2B family. (129 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
NTRK2Neurotrophic receptor tyrosine kinase 2. (477 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
HDAC10Histone deacetylase 10. (663 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa)
SLC29A2Solute carrier family 29 member 2. (458 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
MAPK1Mitogen-activated protein kinase. (333 aa)
GNAI3G protein subunit alpha i3. (354 aa)
SLC18A2Solute carrier family 18 member A2. (517 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (715 aa)
GNAO1G protein subunit alpha o1. (354 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
DRD2D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. (443 aa)
CSDE1Cold shock domain containing E1. (784 aa)
M3Y2Z6_MUSPFUncharacterized protein. (189 aa)
M3Z5X6_MUSPFGuanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (520 aa)
THTyrosine hydroxylase. (495 aa)
H2BC18Histone H2B; Belongs to the histone H2B family. (145 aa)
CREB3cAMP responsive element binding protein 3. (353 aa)
M3Y1V5_MUSPFHistone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (415 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (151 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (76 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1281 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1018 aa)
M3YQU9_MUSPFHistone H3; Belongs to the histone H3 family. (136 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (473 aa)
M3Y070_MUSPFGuanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
CREB5cAMP responsive element binding protein 5. (275 aa)
M3YEN4_MUSPFBZIP domain-containing protein. (358 aa)
PDYNProdynorphin. (257 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1091 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (128 aa)
GRIN3BGlutamate ionotropic receptor NMDA type subunit 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (945 aa)
H6VYP2_MUSPFATP-binding cassette, sub-family F, member 2. (624 aa)
LOC106004309Uncharacterized protein. (102 aa)
M3YBE3_MUSPFHistone domain-containing protein. (105 aa)
H2BC5Histone H2B; Belongs to the histone H2B family. (134 aa)
M3YB62_MUSPFHistone domain-containing protein. (137 aa)
SHC3SHC adaptor protein 3. (425 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (430 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (156 aa)
CALML6Calmodulin like 6. (156 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (386 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (626 aa)
GNB5G protein subunit beta 5. (301 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A. (1135 aa)
M3Y692_MUSPFUncharacterized protein. (362 aa)
SHC1SHC adaptor protein 1. (586 aa)
FOSBFosB proto-oncogene, AP-1 transcription factor subunit. (338 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (399 aa)
SLC29A1Solute carrier family 29 member 1 (Augustine blood group). (678 aa)
CAMKK1Calcium/calmodulin dependent protein kinase kinase 1. (505 aa)
SHC4SHC adaptor protein 4. (624 aa)
CALM2Calmodulin 2; Belongs to the calmodulin family. (149 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1550 aa)
M3YJI6_MUSPFHistone domain-containing protein. (101 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (255 aa)
M3YH29_MUSPFUncharacterized protein. (180 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1276 aa)
ATF6BActivating transcription factor 6 beta. (707 aa)
KRASKRAS proto-oncogene, GTPase. (208 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (469 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (332 aa)
PKIAcAMP-dependent protein kinase inhibitor; Belongs to the PKI family. (76 aa)
ZC2HC1AZinc finger C2HC-type containing 1A. (330 aa)
MACROH2A1Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
SHC2Uncharacterized protein. (539 aa)
ENSMPUP00000019801annotation not available (103 aa)
M3Z785_MUSPFUncharacterized protein; Belongs to the calmodulin family. (149 aa)
CALML5Calmodulin like 5. (149 aa)
M3Z750_MUSPFHistone H2A; Belongs to the histone H2A family. (110 aa)
M3Z6U4_MUSPFGuanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
LOC101680718Histone H3; Belongs to the histone H3 family. (136 aa)
M3Z6J8_MUSPFHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
M3Z687_MUSPFHistone domain-containing protein; Belongs to the histone H2B family. (124 aa)
ENSMPUP00000018988annotation not available (68 aa)
ENSMPUP00000018887annotation not available (68 aa)
M3Z5A7_MUSPFHistone H2A; Belongs to the histone H2A family. (126 aa)
M3Z4T9_MUSPFHistone H2A; Belongs to the histone H2A family. (130 aa)
CRHCorticotropin releasing hormone. (196 aa)
H2AC1Histone H2A; Belongs to the histone H2A family. (131 aa)
H2BC1Histone H2B; Belongs to the histone H2B family. (127 aa)
ENSMPUP00000018499annotation not available (103 aa)
H1-6Histone cluster 1 H1 family member t. (212 aa)
M3Z4I5_MUSPFHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (96 aa)
M3Z4I4_MUSPFHistone domain-containing protein. (136 aa)
M3Z4I3_MUSPFHistone H2B; Belongs to the histone H2B family. (126 aa)
M3Z4I2_MUSPFHistone H3; Belongs to the histone H3 family. (136 aa)
G9L0N9_MUSPFHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
HIST3H2BBHistone H2B; Belongs to the histone H2B family. (126 aa)
H2AWHistone H2A; Belongs to the histone H2A family. (130 aa)
H3-4Histone H3; Belongs to the histone H3 family. (136 aa)
M3Z3Z5_MUSPFHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
H2BC21Histone H2B; Belongs to the histone H2B family. (126 aa)
H2AC20Histone H2A; Belongs to the histone H2A family. (129 aa)
H2AC21Histone H2A; Belongs to the histone H2A family. (130 aa)
GNAI1G protein subunit alpha i1. (354 aa)
H2AZ2Histone H2A; Belongs to the histone H2A family. (148 aa)
DDCDopa decarboxylase. (480 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
HDAC11Histone deacetylase 11. (405 aa)
GNB4G protein subunit beta 4. (340 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (644 aa)
GNB3G protein subunit beta 3. (344 aa)
GNB2G protein subunit beta 2. (340 aa)
HDAC1Histone deacetylase 1. (482 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (959 aa)
PPP1R1BProtein phosphatase 1 regulatory inhibitor subunit 1B. (206 aa)
M3YTL0_MUSPFUncharacterized protein. (233 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1307 aa)
M3YSI0_MUSPFHistone domain-containing protein; Belongs to the histone H2B family. (118 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C. (1109 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
HDAC9Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1068 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
ENSMPUP00000013708annotation not available (136 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (76 aa)
HDAC6Histone deacetylase 6. (1199 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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