STRINGSTRING
C3 C3 JUN JUN M3Z785_MUSPF M3Z785_MUSPF CALML5 CALML5 M3Z6U6_MUSPF M3Z6U6_MUSPF GNAI1 GNAI1 C1S C1S C1R C1R C1RL C1RL CFL2 CFL2 C1QC C1QC C1QB C1QB TMED3 TMED3 M3YUT2_MUSPF M3YUT2_MUSPF M3YUS7_MUSPF M3YUS7_MUSPF EFCAB3 EFCAB3 CCDC125 CCDC125 NOS2 NOS2 RHOA RHOA IL6 IL6 IL12B IL12B GNAI2 GNAI2 MAPK3 MAPK3 NLRP10 NLRP10 NLRP3 NLRP3 CALM2 CALM2 TRAF6 TRAF6 RELA RELA CFL1 CFL1 PYCARD PYCARD TNF TNF ITGAM ITGAM CASP3 CASP3 IL1B IL1B C4A C4A IRF1 IRF1 ITGB2 ITGB2 LY96 LY96 IL10 IL10 C4BPB C4BPB C4BPA C4BPA LOC101691328 LOC101691328 IL1A IL1A NFKB1 NFKB1 CXCL8 CXCL8 FOS FOS MAPK8 MAPK8 IRAK1 IRAK1 IRF8 IRF8 CD14 CD14 CALM1 CALM1 EFCAB13 EFCAB13 CALML6 CALML6 C5 C5 M3Y683_MUSPF M3Y683_MUSPF TIRAP TIRAP ITGB1 ITGB1 ITGA5 ITGA5 CALM3 CALM3 TICAM1 TICAM1 NOD1 NOD1 MAPK13 MAPK13 MAPK14 MAPK14 M3XWU6_MUSPF M3XWU6_MUSPF GNAI3 GNAI3 MAPK1 MAPK1 M3XVI9_MUSPF M3XVI9_MUSPF M3XVG8_MUSPF M3XVG8_MUSPF M3XVG3_MUSPF M3XVG3_MUSPF IL12A IL12A MYD88 MYD88 IRF3 IRF3 MAPK12 MAPK12 MAPK10 MAPK10 MAPK11 MAPK11 CASP7 CASP7 TLR4 TLR4 IL23A IL23A TMED7 TMED7 MAPK9 MAPK9 IRAK4 IRAK4 CALML4 CALML4 SERPING1 SERPING1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
C3Complement C3. (1668 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
M3Z785_MUSPFUncharacterized protein; Belongs to the calmodulin family. (149 aa)
CALML5Calmodulin like 5. (149 aa)
M3Z6U6_MUSPFUncharacterized protein. (457 aa)
GNAI1G protein subunit alpha i1. (354 aa)
C1SComplement C1s; Belongs to the peptidase S1 family. (695 aa)
C1RComplement C1r; Belongs to the peptidase S1 family. (705 aa)
C1RLComplement C1r subcomponent like; Belongs to the peptidase S1 family. (481 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
C1QCComplement C1q C chain. (278 aa)
C1QBComplement C1q B chain. (249 aa)
TMED3Transmembrane p24 trafficking protein 3. (166 aa)
M3YUT2_MUSPFUncharacterized protein. (90 aa)
M3YUS7_MUSPFUncharacterized protein. (74 aa)
EFCAB3EF-hand calcium binding domain 3. (436 aa)
CCDC125Coiled-coil domain containing 125. (513 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1064 aa)
RHOARas homolog family member A. (193 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (210 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (331 aa)
GNAI2G protein subunit alpha i2. (355 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (399 aa)
NLRP10NLR family pyrin domain containing 10. (561 aa)
NLRP3NLR family pyrin domain containing 3. (1035 aa)
CALM2Calmodulin 2; Belongs to the calmodulin family. (149 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
RELARELA proto-oncogene, NF-kB subunit. (511 aa)
CFL1Cofilin 1; Belongs to the actin-binding proteins ADF family. (165 aa)
PYCARDPYD and CARD domain containing. (193 aa)
TNFTumor necrosis factor alpha; Belongs to the tumor necrosis factor family. (233 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1053 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (168 aa)
C4AUncharacterized protein. (1822 aa)
IRF1Interferon regulatory factor. (322 aa)
ITGB2Integrin beta. (782 aa)
LY96Lymphocyte antigen 96. (160 aa)
IL10Interleukin 10. (220 aa)
C4BPBComplement component 4 binding protein beta. (256 aa)
C4BPAUncharacterized protein. (605 aa)
LOC101691328Uncharacterized protein. (212 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (270 aa)
NFKB1Nuclear factor kappa B subunit 1. (971 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (446 aa)
MAPK8Mitogen-activated protein kinase. (397 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (696 aa)
IRF8Interferon regulatory factor 8. (427 aa)
CD14Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (371 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (156 aa)
EFCAB13EF-hand calcium binding domain 13. (792 aa)
CALML6Calmodulin like 6. (156 aa)
C5Complement C5. (1678 aa)
M3Y683_MUSPFUncharacterized protein. (1658 aa)
TIRAPTIR domain containing adaptor protein. (227 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1104 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (151 aa)
TICAM1TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (689 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (952 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
M3XWU6_MUSPFC-type lectin domain-containing protein. (248 aa)
GNAI3G protein subunit alpha i3. (354 aa)
MAPK1Mitogen-activated protein kinase. (333 aa)
M3XVI9_MUSPFUncharacterized protein. (146 aa)
M3XVG8_MUSPFUncharacterized protein. (1073 aa)
M3XVG3_MUSPFUncharacterized protein. (80 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (222 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
IRF3Interferon regulatory factor 3. (421 aa)
MAPK12Mitogen-activated protein kinase. (287 aa)
MAPK10Mitogen-activated protein kinase. (384 aa)
MAPK11Mitogen-activated protein kinase. (434 aa)
CASP7Caspase 7; Belongs to the peptidase C14A family. (301 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (833 aa)
IL23AInterleukin 23 subunit alpha. (195 aa)
TMED7GOLD domain-containing protein. (224 aa)
MAPK9Mitogen-activated protein kinase. (398 aa)
IRAK4Interleukin-1 receptor-associated kinase 4. (460 aa)
CALML4Calmodulin like 4. (153 aa)
SERPING1Serpin family G member 1; Belongs to the serpin family. (479 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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