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| | TLR2 | Toll like receptor 2; Belongs to the Toll-like receptor family. (785 aa) |
| | JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa) |
| | TLR6 | Toll like receptor 6; Belongs to the Toll-like receptor family. (793 aa) |
| | IFNB1 | Interferon beta. (186 aa) |
| | GNAI1 | G protein subunit alpha i1. (354 aa) |
| | ADCY1 | Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1130 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | TGFB1 | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (166 aa) |
| | PPP2R1A | Protein phosphatase 2 scaffold subunit Aalpha. (590 aa) |
| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (152 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (501 aa) |
| | NFKBIA | NFKB inhibitor alpha. (314 aa) |
| | C1QC | Complement C1q C chain. (278 aa) |
| | C1QB | Complement C1q B chain. (249 aa) |
| | SERPINE1 | Serpin peptidase inhibitor, clade E, member 1; Belongs to the serpin family. (400 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa) |
| | M3YWA8_MUSPF | Uncharacterized protein. (726 aa) |
| | CD247 | CD247 molecule. (185 aa) |
| | FASLG | Fas ligand; Belongs to the tumor necrosis factor family. (275 aa) |
| | M3YU65_MUSPF | C-C motif chemokine. (93 aa) |
| | M3YU63_MUSPF | C-C motif chemokine. (107 aa) |
| | ACE | Angiotensin-converting enzyme. (1247 aa) |
| | M3YU47_MUSPF | C-C motif chemokine. (93 aa) |
| | CCL5 | C-C motif chemokine. (91 aa) |
| | M3YU28_MUSPF | Angiotensin-converting enzyme. (753 aa) |
| | IFNGR1 | Interferon gamma receptor 1. (474 aa) |
| | CCL2 | C-C motif chemokine. (101 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (725 aa) |
| | NOS2 | Nitric oxide synthase; Produces nitric oxide (NO). (1064 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (210 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (331 aa) |
| | GNAI2 | G protein subunit alpha i2. (355 aa) |
| | M3YNJ8_MUSPF | Uncharacterized protein. (461 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1233 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (399 aa) |
| | GNAQ | G protein subunit alpha q. (301 aa) |
| | GNA14 | G protein subunit alpha 14. (355 aa) |
| | TGFBR2 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (445 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa) |
| | M3YJV8_MUSPF | Uncharacterized protein. (1327 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (511 aa) |
| | TNF | Tumor necrosis factor alpha; Belongs to the tumor necrosis factor family. (233 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (168 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (284 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | IL10 | Interleukin 10. (220 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (412 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (971 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (446 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (397 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (696 aa) |
| | M3YB13_MUSPF | Ig-like domain-containing protein. (159 aa) |
| | M3YAZ8_MUSPF | Ig-like domain-containing protein. (158 aa) |
| | M3YAZ1_MUSPF | Ig-like domain-containing protein. (221 aa) |
| | M3YAY8_MUSPF | Ig-like domain-containing protein. (227 aa) |
| | TRBV16 | T cell receptor beta variable 16 (gene/pseudogene). (118 aa) |
| | M3YAX3_MUSPF | Ig-like domain-containing protein. (160 aa) |
| | TRBV19 | T cell receptor beta variable 19. (158 aa) |
| | M3YAW1_MUSPF | IGv domain-containing protein. (129 aa) |
| | TRBV25-1 | T cell receptor beta variable 25-1. (125 aa) |
| | M3YAV2_MUSPF | Ig-like domain-containing protein. (141 aa) |
| | M3YAT2_MUSPF | Ig-like domain-containing protein. (186 aa) |
| | PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1187 aa) |
| | PPP2R2B | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (501 aa) |
| | M3Y7P9_MUSPF | Ig-like domain-containing protein. (166 aa) |
| | M3Y7P0_MUSPF | Uncharacterized protein. (54 aa) |
| | TRAV18 | T cell receptor alpha variable 18. (159 aa) |
| | M3Y7K5_MUSPF | Ig-like domain-containing protein. (163 aa) |
| | PPP2R2C | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa) |
| | M3Y7D3_MUSPF | DUF1968 domain-containing protein. (157 aa) |
| | C3 | Complement C3. (1668 aa) |
| | M3Y692_MUSPF | Uncharacterized protein. (362 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | FAS | Fas cell surface death receptor. (311 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1096 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | TICAM1 | TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (689 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (216 aa) |
| | GNAL | G protein subunit alpha L. (380 aa) |
| | CD3G | T-cell surface glycoprotein CD3 gamma chain. (180 aa) |
| | CD3D | CD3d molecule. (169 aa) |
| | CD3E | CD3 epsilon antigen. (186 aa) |
| | CALR | Calreticulin. (417 aa) |
| | TGFB2 | Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...] (414 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (366 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | GNA15 | G protein subunit alpha 15. (374 aa) |
| | MAP2K4 | Mitogen-activated protein kinase kinase 4. (281 aa) |
| | GNA11 | G protein subunit alpha 11. (334 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (789 aa) |
| | GNAO1 | G protein subunit alpha o1. (354 aa) |
| | GNAI3 | G protein subunit alpha i3. (354 aa) |
| | KNG1 | Kininogen 1. (661 aa) |
| | PPP2R2A | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (487 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (333 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (222 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa) |
| | AADACL2 | Arylacetamide deacetylase like 2. (401 aa) |
| | PPP2R2D | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (423 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (287 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (384 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (434 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (833 aa) |
| | IFNGR2 | Interferon gamma receptor 2. (341 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (495 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (398 aa) |
| | IRAK4 | Interleukin-1 receptor-associated kinase 4. (460 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (484 aa) |
| | CFLAR | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (482 aa) |
