STRINGSTRING
XIAP XIAP MAP2K3 MAP2K3 CASP8 CASP8 IRAK4 IRAK4 LOC101673202 LOC101673202 MAPK9 MAPK9 JAK1 JAK1 ITGA6 ITGA6 M3XPU5_MUSPF M3XPU5_MUSPF IL10RB IL10RB TLR4 TLR4 CD40LG CD40LG M3XS58_MUSPF M3XS58_MUSPF M3XS76_MUSPF M3XS76_MUSPF HLA-DMA HLA-DMA HLA-DOA HLA-DOA HLA-DPA1 HLA-DPA1 AKT1 AKT1 MAPK11 MAPK11 MAPK10 MAPK10 MAPK12 MAPK12 MYD88 MYD88 IL12A IL12A LAMB3 LAMB3 MAPK1 MAPK1 M3XVS8_MUSPF M3XVS8_MUSPF GNAI3 GNAI3 GNAO1 GNAO1 PPIF PPIF MAPK14 MAPK14 MAPK13 MAPK13 TGFB2 TGFB2 IL10RA IL10RA C7orf31 C7orf31 LAMA1 LAMA1 JAK2 JAK2 LDLR LDLR LAMA3 LAMA3 M3Y362_MUSPF M3Y362_MUSPF ITGB1 ITGB1 TYK2 TYK2 BIRC2 BIRC2 BIRC3 BIRC3 M3Y779_MUSPF M3Y779_MUSPF M3Y7C9_MUSPF M3Y7C9_MUSPF M3Y8D0_MUSPF M3Y8D0_MUSPF LAMA5 LAMA5 PIK3R5 PIK3R5 PIK3R6 PIK3R6 BIRC7 BIRC7 IRAK1 IRAK1 MAP3K7 MAP3K7 MAPK8 MAPK8 NFKB1 NFKB1 M3YDZ3_MUSPF M3YDZ3_MUSPF M3YE13_MUSPF M3YE13_MUSPF ALOX5 ALOX5 IKBKG IKBKG IL10 IL10 LY96 LY96 LAMA4 LAMA4 STAT3 STAT3 M3YH07_MUSPF M3YH07_MUSPF M3YHB9_MUSPF M3YHB9_MUSPF CASP3 CASP3 TNF TNF LAMC1 LAMC1 LAMC2 LAMC2 RELA RELA TRAF6 TRAF6 M3YM35_MUSPF M3YM35_MUSPF IFNGR2 IFNGR2 STAT1 STAT1 LAMC3 LAMC3 MAPK3 MAPK3 IKBKB IKBKB BAD BAD GNAI2 GNAI2 PPP1R14B PPP1R14B IL12B IL12B TAB1 TAB1 LAMB2 LAMB2 MAP2K6 MAP2K6 NOS2 NOS2 LAMA2 LAMA2 CIITA CIITA IFNGR1 IFNGR1 LOC101678178 LOC101678178 PDPK1 PDPK1 AKT3 AKT3 NFKBIA NFKBIA CASP9 CASP9 BCL2 BCL2 TNFRSF1A TNFRSF1A CHUK CHUK IFNG IFNG CD40 CD40 TGFB1 TGFB1 AKT2 AKT2 NFKBIB NFKBIB BCL2L1 BCL2L1 TAB2 TAB2 LAMB4 LAMB4 LAMB1 LAMB1 PIK3CG PIK3CG GNAI1 GNAI1 HSPA1L HSPA1L M3Z4Y0_MUSPF M3Z4Y0_MUSPF TLR2 TLR2 M3Z6D9_MUSPF M3Z6D9_MUSPF HSPA8 HSPA8 HSPA2 HSPA2 CCR5 CCR5 SOCS1 SOCS1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
XIAPX-linked inhibitor of apoptosis. (497 aa)
MAP2K3Mitogen-activated protein kinase kinase 3. (396 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (484 aa)
IRAK4Interleukin-1 receptor-associated kinase 4. (460 aa)
LOC101673202IRG-type G domain-containing protein. (400 aa)
MAPK9Mitogen-activated protein kinase. (398 aa)
JAK1Tyrosine-protein kinase. (1153 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1021 aa)
M3XPU5_MUSPFIRG-type G domain-containing protein. (383 aa)
IL10RBInterleukin 10 receptor subunit beta. (359 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (833 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (260 aa)
M3XS58_MUSPFIg-like domain-containing protein. (171 aa)
M3XS76_MUSPFIg-like domain-containing protein. (263 aa)
HLA-DMAMajor histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (261 aa)
HLA-DOAMajor histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (250 aa)
HLA-DPA1Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (242 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
MAPK11Mitogen-activated protein kinase. (434 aa)
MAPK10Mitogen-activated protein kinase. (384 aa)
MAPK12Mitogen-activated protein kinase. (287 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (222 aa)
LAMB3Laminin subunit beta 3. (1174 aa)
MAPK1Mitogen-activated protein kinase. (333 aa)
M3XVS8_MUSPFCytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
GNAI3G protein subunit alpha i3. (354 aa)
GNAO1G protein subunit alpha o1. (354 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (211 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
TGFB2Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...] (414 aa)
IL10RAInterleukin 10 receptor subunit alpha. (611 aa)
C7orf31Chromosome 7 open reading frame 31. (589 aa)
LAMA1Laminin subunit alpha 1. (3086 aa)
JAK2Tyrosine-protein kinase. (1130 aa)
LDLRLow density lipoprotein receptor. (856 aa)
LAMA3Laminin subunit alpha 3. (3330 aa)
M3Y362_MUSPFUncharacterized protein; Belongs to the heat shock protein 70 family. (646 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
TYK2Tyrosine-protein kinase. (1182 aa)
BIRC2Baculoviral IAP repeat containing 2. (570 aa)
BIRC3Baculoviral IAP repeat containing 3. (604 aa)
M3Y779_MUSPFIg-like domain-containing protein. (269 aa)
M3Y7C9_MUSPFIg-like domain-containing protein. (266 aa)
M3Y8D0_MUSPFUncharacterized protein; Belongs to the heat shock protein 70 family. (617 aa)
LAMA5Laminin subunit alpha 5. (3008 aa)
PIK3R5Phosphoinositide-3-kinase regulatory subunit 5. (778 aa)
PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (755 aa)
BIRC7Baculoviral IAP repeat containing 7. (300 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (696 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
MAPK8Mitogen-activated protein kinase. (397 aa)
NFKB1Nuclear factor kappa B subunit 1. (971 aa)
M3YDZ3_MUSPFMHC_II_alpha domain-containing protein. (236 aa)
M3YE13_MUSPFIg-like domain-containing protein. (233 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (412 aa)
IL10Interleukin 10. (220 aa)
LY96Lymphocyte antigen 96. (160 aa)
LAMA4Laminin subunit alpha 4. (1931 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
M3YH07_MUSPFIg-like domain-containing protein. (265 aa)
M3YHB9_MUSPFUncharacterized protein; Belongs to the heat shock protein 70 family. (642 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
TNFTumor necrosis factor alpha; Belongs to the tumor necrosis factor family. (233 aa)
LAMC1Laminin subunit gamma 1. (1573 aa)
LAMC2Laminin subunit gamma 2. (1191 aa)
RELARELA proto-oncogene, NF-kB subunit. (511 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
M3YM35_MUSPFUncharacterized protein; Belongs to the heat shock protein 70 family. (567 aa)
IFNGR2Interferon gamma receptor 2. (341 aa)
STAT1Signal transducer and activator of transcription. (750 aa)
LAMC3Laminin subunit gamma 3. (1516 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (399 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
BADBCL2 associated agonist of cell death. (168 aa)
GNAI2G protein subunit alpha i2. (355 aa)
PPP1R14BProtein phosphatase 1 regulatory inhibitor subunit 14B. (145 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (331 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa)
LAMB2Laminin subunit beta 2. (1801 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1064 aa)
LAMA2Laminin subunit alpha 2. (3137 aa)
CIITAClass II major histocompatibility complex transactivator. (1109 aa)
IFNGR1Interferon gamma receptor 1. (474 aa)
LOC101678178Ig-like domain-containing protein; Belongs to the MHC class II family. (196 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (531 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (451 aa)
BCL2BCL2 apoptosis regulator. (207 aa)
TNFRSF1ATNF receptor superfamily member 1A. (501 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (166 aa)
CD40CD40 molecule. (277 aa)
TGFB1Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
NFKBIBNFKB inhibitor beta. (354 aa)
BCL2L1BCL2 like 1. (233 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
LAMB4Laminin subunit beta 4. (1791 aa)
LAMB1Laminin subunit beta 1. (1786 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa)
GNAI1G protein subunit alpha i1. (354 aa)
HSPA1LHeat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. (641 aa)
M3Z4Y0_MUSPFCytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
TLR2Toll like receptor 2; Belongs to the Toll-like receptor family. (785 aa)
M3Z6D9_MUSPFIRG-type G domain-containing protein. (421 aa)
HSPA8Uncharacterized protein; Belongs to the heat shock protein 70 family. (643 aa)
HSPA2Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (635 aa)
CCR5C-C motif chemokine receptor 5 (gene/pseudogene); Belongs to the G-protein coupled receptor 1 family. (352 aa)
SOCS1Suppressor of cytokine signaling 1. (216 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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