STRINGSTRING
ATF2 ATF2 M3YRC5_MUSPF M3YRC5_MUSPF PTRHD1 PTRHD1 ADCY3 ADCY3 CDKN1A CDKN1A PIK3R1 PIK3R1 ADCY6 ADCY6 TBPL1 TBPL1 MAP3K3 MAP3K3 LOC101678178 LOC101678178 ADCY9 ADCY9 CREBBP CREBBP RANBP3L RANBP3L ANAPC2 ANAPC2 LCK LCK CRTC1 CRTC1 CRTC3 CRTC3 M3YWA8_MUSPF M3YWA8_MUSPF AKT3 AKT3 JAK3 JAK3 E2F2 E2F2 CDKN2B CDKN2B M3YX09_MUSPF M3YX09_MUSPF CDKN2A CDKN2A IL15 IL15 M3YXL2_MUSPF M3YXL2_MUSPF NFKBIA NFKBIA TSPO TSPO M3YY34_MUSPF M3YY34_MUSPF IL2RA IL2RA TNFRSF13C TNFRSF13C EP300 EP300 TRRAP TRRAP NFATC1 NFATC1 ANAPC4 ANAPC4 CD4 CD4 NFKB2 NFKB2 LTBR LTBR TNFRSF1A TNFRSF1A CHUK CHUK M3YZX8_MUSPF M3YZX8_MUSPF PIK3CA PIK3CA SLC25A31 SLC25A31 IL2 IL2 CCNA2 CCNA2 MAD2L1 MAD2L1 NFATC2 NFATC2 CD40 CD40 TGFB1 TGFB1 AKT2 AKT2 ZFP36 ZFP36 E2F1 E2F1 BCL2L1 BCL2L1 MAD1L1 MAD1L1 ADCY1 ADCY1 M3Z4V0_MUSPF M3Z4V0_MUSPF M3Z5V4_MUSPF M3Z5V4_MUSPF M3Z7D9_MUSPF M3Z7D9_MUSPF TLNRD1 TLNRD1 JUN JUN M3Y2A4_MUSPF M3Y2A4_MUSPF XPO1 XPO1 CREB3L1 CREB3L1 CREB3 CREB3 NFATC4 NFATC4 ADCY4 ADCY4 M3Y2Z6_MUSPF M3Y2Z6_MUSPF CSDE1 CSDE1 PRKACB PRKACB TBPL2 TBPL2 NRP1 NRP1 ATM ATM ESPL1 ESPL1 PIK3CD PIK3CD M3Y4E6_MUSPF M3Y4E6_MUSPF RANBP3 RANBP3 CHEK1 CHEK1 ANAPC10 ANAPC10 TGFBR1 TGFBR1 ICAM1 ICAM1 NFATC3 NFATC3 CDKN2C CDKN2C ADCY2 ADCY2 MMP7 MMP7 TBP TBP M3Y779_MUSPF M3Y779_MUSPF M3Y7C9_MUSPF M3Y7C9_MUSPF M3Y7D3_MUSPF M3Y7D3_MUSPF M3Y7K5_MUSPF M3Y7K5_MUSPF TRAV18 TRAV18 MAP3K1 MAP3K1 M3Y8H4_MUSPF M3Y8H4_MUSPF M3Y8I3_MUSPF M3Y8I3_MUSPF MSX1 MSX1 CREB3L4 CREB3L4 CRTC2 CRTC2 CCNE1 CCNE1 TCF3 TCF3 CDC27 CDC27 M3YAG0_MUSPF M3YAG0_MUSPF ETS2 ETS2 M3YAT2_MUSPF M3YAT2_MUSPF ETS1 ETS1 M3YAV2_MUSPF M3YAV2_MUSPF TRBV25-1 TRBV25-1 TLN1 TLN1 E2F3 E2F3 CREB5 CREB5 CREB3L3 CREB3L3 M3Y027_MUSPF M3Y027_MUSPF M3XZW3_MUSPF M3XZW3_MUSPF CCND1 CCND1 ADCY5 ADCY5 CD3G CD3G CD3D CD3D CD3E CD3E CALR CALR TGFB2 TGFB2 CCNB2 CCNB2 M3XYE2_MUSPF M3XYE2_MUSPF SPI1 SPI1 RAN RAN CREB3L2 CREB3L2 DLG1 DLG1 MAP2K4 MAP2K4 PPP3CC PPP3CC PPP3CB PPP3CB BAX BAX VDAC2 VDAC2 ADCY7 ADCY7 MAPK1 MAPK1 PRKACA PRKACA M3XV12_MUSPF M3XV12_MUSPF BUB3 BUB3 MAPK10 MAPK10 AKT1 AKT1 ANAPC7 ANAPC7 ANAPC5 ANAPC5 M3XSN5_MUSPF M3XSN5_MUSPF M3XSL7_MUSPF M3XSL7_MUSPF CDK4 CDK4 HLA-DPA1 HLA-DPA1 HLA-DOA HLA-DOA HLA-DMA HLA-DMA M3XS76_MUSPF M3XS76_MUSPF M3XS58_MUSPF M3XS58_MUSPF CCNA1 CCNA1 SLC25A5 SLC25A5 RB1 RB1 ADCY8 ADCY8 XIAP XIAP MYC MYC M3XQA1_MUSPF M3XQA1_MUSPF M3XQ51_MUSPF M3XQ51_MUSPF M3XPU6_MUSPF M3XPU6_MUSPF CDK2 CDK2 SMAD2 SMAD2 M3XP26_MUSPF M3XP26_MUSPF JAK1 JAK1 CANX CANX TLN2 TLN2 MAPK9 MAPK9 CREB1 CREB1 MAP2K1 MAP2K1 SMAD3 SMAD3 M3YAY8_MUSPF M3YAY8_MUSPF M3YAZ8_MUSPF M3YAZ8_MUSPF MAP3K14 MAP3K14 M3YB13_MUSPF M3YB13_MUSPF SMAD4 SMAD4 CCNE2 CCNE2 TERT TERT TP53 TP53 PIK3CB PIK3CB MAPK8 MAPK8 CDC16 CDC16 FOS FOS M3YD44_MUSPF M3YD44_MUSPF EGR1 EGR1 NFKB1 NFKB1 PPP3CA PPP3CA ANAPC1 ANAPC1 CDC23 CDC23 M3YDZ3_MUSPF M3YDZ3_MUSPF M3YE13_MUSPF M3YE13_MUSPF M3YE76_MUSPF M3YE76_MUSPF IKBKG IKBKG M3YEN4_MUSPF M3YEN4_MUSPF M3YFN8_MUSPF M3YFN8_MUSPF ITGB2 ITGB2 KRAS KRAS M3YFW7_MUSPF M3YFW7_MUSPF ATF6B ATF6B VAC14 VAC14 STAT5A STAT5A STAT5B STAT5B KAT2A KAT2A M3YH07_MUSPF M3YH07_MUSPF M3YH29_MUSPF M3YH29_MUSPF B2M B2M EGR2 EGR2 SLC25A4 SLC25A4 M3YIU0_MUSPF M3YIU0_MUSPF TNF TNF LTA LTA M3YJ13_MUSPF M3YJ13_MUSPF FOSL1 FOSL1 CSF2 CSF2 KAT5 KAT5 RELA RELA ELK4 ELK4 TGFBR2 TGFBR2 ATR ATR NFYB NFYB IL1R2 IL1R2 IL1R1 IL1R1 ITGAL ITGAL M3YLR8_MUSPF M3YLR8_MUSPF MAPK3 MAPK3 IL2RB IL2RB MSX2 MSX2 IKBKB IKBKB POLB POLB M3YMR6_MUSPF M3YMR6_MUSPF M3YNJ8_MUSPF M3YNJ8_MUSPF SRF SRF PTK7 PTK7 M3YP02_MUSPF M3YP02_MUSPF M3YP04_MUSPF M3YP04_MUSPF M3YP86_MUSPF M3YP86_MUSPF M3YPM9_MUSPF M3YPM9_MUSPF ELK1 ELK1 CCND3 CCND3 CHEK2 CHEK2 IL6 IL6 TSPO2 TSPO2 CDC20 CDC20 SLC2A1 SLC2A1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
M3YRC5_MUSPFIg-like domain-containing protein; Belongs to the MHC class I family. (357 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
TBPL1TATA-box binding protein like 1. (186 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (647 aa)
LOC101678178Ig-like domain-containing protein; Belongs to the MHC class II family. (196 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
CREBBPCREB binding protein. (2442 aa)
RANBP3LRAN binding protein 3 like. (490 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (818 aa)
LCKTyrosine-protein kinase. (509 aa)
CRTC1CREB regulated transcription coactivator 1. (654 aa)
CRTC3CREB regulated transcription coactivator 3. (554 aa)
M3YWA8_MUSPFUncharacterized protein. (726 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
JAK3Tyrosine-protein kinase. (1107 aa)
E2F2E2F transcription factor 2. (440 aa)
CDKN2BCyclin dependent kinase inhibitor 2B. (131 aa)
M3YX09_MUSPFUncharacterized protein. (126 aa)
CDKN2ACyclin dependent kinase inhibitor 2A. (152 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
M3YXL2_MUSPFUncharacterized protein. (912 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
TSPOTranslocator protein. (169 aa)
M3YY34_MUSPFSushi domain-containing protein. (279 aa)
IL2RAInterleukin 2 receptor subunit alpha. (267 aa)
TNFRSF13CTNF receptor superfamily member 13C. (187 aa)
EP300E1A binding protein p300. (2425 aa)
TRRAPTransformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3276 aa)
NFATC1Nuclear factor of activated T cells 1. (701 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (807 aa)
CD4CD4. (462 aa)
NFKB2Nuclear factor kappa B subunit 2. (900 aa)
LTBRLymphotoxin beta receptor. (420 aa)
TNFRSF1ATNF receptor superfamily member 1A. (501 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
M3YZX8_MUSPFUncharacterized protein. (144 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
SLC25A31Solute carrier family 25 member 31; Belongs to the mitochondrial carrier (TC 2.A.29) family. (323 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (152 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (432 aa)
MAD2L1Mitotic arrest deficient 2 like 1. (205 aa)
NFATC2Nuclear factor of activated T cells 2. (912 aa)
CD40CD40 molecule. (277 aa)
TGFB1Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
ZFP36ZFP36 ring finger protein. (327 aa)
E2F1E2F transcription factor 1. (354 aa)
BCL2L1BCL2 like 1. (233 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (737 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1130 aa)
M3Z4V0_MUSPFRanBD1 domain-containing protein. (208 aa)
M3Z5V4_MUSPFRanBD1 domain-containing protein. (209 aa)
M3Z7D9_MUSPFUncharacterized protein. (283 aa)
TLNRD1Talin rod domain containing 1. (362 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
M3Y2A4_MUSPFUncharacterized protein; Belongs to the FPP/GGPP synthase family. (421 aa)
XPO1Exportin 1. (1071 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (520 aa)
CREB3cAMP responsive element binding protein 3. (353 aa)
NFATC4Nuclear factor of activated T cells 4. (831 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1105 aa)
M3Y2Z6_MUSPFUncharacterized protein. (189 aa)
CSDE1Cold shock domain containing E1. (784 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
TBPL2TATA-box binding protein like 2. (350 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3057 aa)
ESPL1Extra spindle pole bodies like 1, separase. (2111 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
M3Y4E6_MUSPFUncharacterized protein. (160 aa)
RANBP3RAN binding protein 3. (495 aa)
CHEK1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (476 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (480 aa)
ICAM1Intercellular adhesion molecule 1. (589 aa)
NFATC3Nuclear factor of activated T cells 3. (1037 aa)
CDKN2CCyclin dependent kinase inhibitor 2C. (168 aa)
ADCY2Adenylate cyclase 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (880 aa)
MMP7Matrix metallopeptidase 7. (241 aa)
TBPTATA-box binding protein. (323 aa)
M3Y779_MUSPFIg-like domain-containing protein. (269 aa)
M3Y7C9_MUSPFIg-like domain-containing protein. (266 aa)
M3Y7D3_MUSPFDUF1968 domain-containing protein. (157 aa)
M3Y7K5_MUSPFIg-like domain-containing protein. (163 aa)
TRAV18T cell receptor alpha variable 18. (159 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1343 aa)
M3Y8H4_MUSPFWD_REPEATS_REGION domain-containing protein. (146 aa)
M3Y8I3_MUSPFWD_REPEATS_REGION domain-containing protein. (118 aa)
MSX1Msh homeobox 1. (303 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (386 aa)
CRTC2CREB regulated transcription coactivator 2. (642 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (410 aa)
TCF3Transcription factor 3. (652 aa)
CDC27Cell division cycle 27. (825 aa)
M3YAG0_MUSPFBUB1 N-terminal domain-containing protein. (1062 aa)
ETS2Protein C-ets-2; Transcription factor; Belongs to the ETS family. (469 aa)
M3YAT2_MUSPFIg-like domain-containing protein. (186 aa)
ETS1ETS proto-oncogene 1, transcription factor. (443 aa)
M3YAV2_MUSPFIg-like domain-containing protein. (141 aa)
TRBV25-1T cell receptor beta variable 25-1. (125 aa)
TLN1Talin 1. (2541 aa)
E2F3E2F transcription factor 3. (340 aa)
CREB5cAMP responsive element binding protein 5. (275 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (473 aa)
M3Y027_MUSPFProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
M3XZW3_MUSPFFibronectin type-III domain-containing protein. (374 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1018 aa)
CD3GT-cell surface glycoprotein CD3 gamma chain. (180 aa)
CD3DCD3d molecule. (169 aa)
CD3ECD3 epsilon antigen. (186 aa)
CALRCalreticulin. (417 aa)
TGFB2Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...] (414 aa)
CCNB2Cyclin B2; Belongs to the cyclin family. (397 aa)
M3XYE2_MUSPFRanBD1 domain-containing protein. (209 aa)
SPI1Spi-1 proto-oncogene. (257 aa)
RANGTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (214 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (927 aa)
MAP2K4Mitogen-activated protein kinase kinase 4. (281 aa)
PPP3CCSerine/threonine-protein phosphatase. (525 aa)
PPP3CBSerine/threonine-protein phosphatase. (479 aa)
BAXBCL2 associated X, apoptosis regulator. (192 aa)
VDAC2Voltage dependent anion channel 2. (294 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
MAPK1Mitogen-activated protein kinase. (333 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
M3XV12_MUSPFUncharacterized protein; Belongs to the FPP/GGPP synthase family. (345 aa)
BUB3BUB3 mitotic checkpoint protein. (328 aa)
MAPK10Mitogen-activated protein kinase. (384 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ANAPC7Anaphase promoting complex subunit 7. (598 aa)
ANAPC5Anaphase promoting complex subunit 5. (711 aa)
M3XSN5_MUSPFUncharacterized protein; Belongs to the MHC class I family. (304 aa)
M3XSL7_MUSPFIg-like domain-containing protein; Belongs to the MHC class I family. (266 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (305 aa)
HLA-DPA1Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (242 aa)
HLA-DOAMajor histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (250 aa)
HLA-DMAMajor histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (261 aa)
M3XS76_MUSPFIg-like domain-containing protein. (263 aa)
M3XS58_MUSPFIg-like domain-containing protein. (171 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (421 aa)
SLC25A5Solute carrier family 25 member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. (352 aa)
RB1RB transcriptional corepressor 1. (948 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
XIAPX-linked inhibitor of apoptosis. (497 aa)
MYCV-myc myelocytomatosis viral oncoprotein-like protein. (453 aa)
M3XQA1_MUSPFUncharacterized protein. (175 aa)
M3XQ51_MUSPFUncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (271 aa)
M3XPU6_MUSPFIg-like domain-containing protein; Belongs to the MHC class I family. (368 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (334 aa)
SMAD2Mothers against decapentaplegic homolog. (495 aa)
M3XP26_MUSPFUncharacterized protein. (265 aa)
JAK1Tyrosine-protein kinase. (1153 aa)
CANXCalnexin. (484 aa)
TLN2Talin 2. (2542 aa)
MAPK9Mitogen-activated protein kinase. (398 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
SMAD3Mothers against decapentaplegic homolog. (414 aa)
M3YAY8_MUSPFIg-like domain-containing protein. (227 aa)
M3YAZ8_MUSPFIg-like domain-containing protein. (158 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (954 aa)
M3YB13_MUSPFIg-like domain-containing protein. (159 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (404 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1113 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (375 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
MAPK8Mitogen-activated protein kinase. (397 aa)
CDC16Cell division cycle 16. (605 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (446 aa)
M3YD44_MUSPFCyclin N-terminal domain-containing protein; Belongs to the cyclin family. (291 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (544 aa)
NFKB1Nuclear factor kappa B subunit 1. (971 aa)
PPP3CASerine/threonine-protein phosphatase. (461 aa)
ANAPC1Anaphase promoting complex subunit 1. (1944 aa)
CDC23Cell division cycle 23. (590 aa)
M3YDZ3_MUSPFMHC_II_alpha domain-containing protein. (236 aa)
M3YE13_MUSPFIg-like domain-containing protein. (233 aa)
M3YE76_MUSPFHomeobox domain-containing protein. (208 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (412 aa)
M3YEN4_MUSPFBZIP domain-containing protein. (358 aa)
M3YFN8_MUSPFUncharacterized protein. (283 aa)
ITGB2Integrin beta. (782 aa)
KRASKRAS proto-oncogene, GTPase. (208 aa)
M3YFW7_MUSPFUncharacterized protein. (360 aa)
ATF6BActivating transcription factor 6 beta. (707 aa)
VAC14VAC14 component of PIKFYVE complex. (784 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
STAT5BSignal transducer and activator of transcription. (691 aa)
KAT2ALysine acetyltransferase 2A. (869 aa)
M3YH07_MUSPFIg-like domain-containing protein. (265 aa)
M3YH29_MUSPFUncharacterized protein. (180 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (128 aa)
EGR2Early growth response 2. (485 aa)
SLC25A4Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
M3YIU0_MUSPFRING-type domain-containing protein. (84 aa)
TNFTumor necrosis factor alpha; Belongs to the tumor necrosis factor family. (233 aa)
LTALymphotoxin alpha; Belongs to the tumor necrosis factor family. (204 aa)
M3YJ13_MUSPFMHC_I-like_Ag-recog domain-containing protein; Belongs to the MHC class I family. (88 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (271 aa)
CSF2Colony stimulating factor 2. (148 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa)
RELARELA proto-oncogene, NF-kB subunit. (511 aa)
ELK4ETS transcription factor ELK4. (485 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (445 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa)
NFYBNuclear transcription factor Y subunit beta. (207 aa)
IL1R2Interleukin 1 receptor type 2. (414 aa)
IL1R1Interleukin 1 receptor type 1. (573 aa)
ITGALIntegrin subunit alpha L; Belongs to the integrin alpha chain family. (1166 aa)
M3YLR8_MUSPFRHD domain-containing protein. (249 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (399 aa)
IL2RBInterleukin 2 receptor subunit beta. (554 aa)
MSX2Msh homeobox 2. (267 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
POLBDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa)
M3YMR6_MUSPFUncharacterized protein. (292 aa)
M3YNJ8_MUSPFUncharacterized protein. (461 aa)
SRFSerum response factor. (508 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa)
M3YP02_MUSPFPCAF_N domain-containing protein. (92 aa)
M3YP04_MUSPFUncharacterized protein. (675 aa)
M3YP86_MUSPFUncharacterized protein. (201 aa)
M3YPM9_MUSPFBZIP domain-containing protein. (351 aa)
ELK1ETS transcription factor ELK1. (435 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (294 aa)
CHEK2Checkpoint kinase 2. (544 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (210 aa)
TSPO2Translocator protein 2. (171 aa)
CDC20Cell division cycle 20-like protein. (499 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (480 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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