STRINGSTRING
FLT3 FLT3 IKBKG IKBKG NFKB1 NFKB1 RUNX1T1 RUNX1T1 PIK3CB PIK3CB LEF1 LEF1 TCF7L1 TCF7L1 CD14 CD14 DUSP6 DUSP6 CEBPA CEBPA CEBPE CEBPE PIK3CD PIK3CD KIT KIT CSDE1 CSDE1 M3Y2Z6_MUSPF M3Y2Z6_MUSPF M3Y2L0_MUSPF M3Y2L0_MUSPF SOS2 SOS2 M3Y027_MUSPF M3Y027_MUSPF CCND1 CCND1 SPI1 SPI1 ZBTB16 ZBTB16 RPS6KB2 RPS6KB2 PPARD PPARD BRAF BRAF MAPK1 MAPK1 AKT1 AKT1 M3XSG3_MUSPF M3XSG3_MUSPF TCF7L2 TCF7L2 CCNA1 CCNA1 RUNX1 RUNX1 MYC MYC MAP2K1 MAP2K1 PER2 PER2 AKT2 AKT2 CCNA2 CCNA2 PML PML PIK3CA PIK3CA RAF1 RAF1 CHUK CHUK MTOR MTOR AKT3 AKT3 M3YWA8_MUSPF M3YWA8_MUSPF BCL2A1 BCL2A1 MPO MPO RPS6KB1 RPS6KB1 RARA RARA PIK3R1 PIK3R1 PIM1 PIM1 CSF1R CSF1R GRB2 GRB2 PIM2 PIM2 ARAF ARAF PPP1R14B PPP1R14B M3YNJ8_MUSPF M3YNJ8_MUSPF BAD BAD IKBKB IKBKB MAPK3 MAPK3 RELA RELA M3YJF2_MUSPF M3YJF2_MUSPF CSF2 CSF2 ITGAM ITGAM JUP JUP M3YH29_MUSPF M3YH29_MUSPF STAT5B STAT5B STAT5A STAT5A STAT3 STAT3 SOS1 SOS1 KRAS KRAS TCF7 TCF7 EIF4EBP1 EIF4EBP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (974 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (412 aa)
NFKB1Nuclear factor kappa B subunit 1. (971 aa)
RUNX1T1RUNX1 partner transcriptional co-repressor 1. (604 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
LEF1Lymphoid enhancer binding factor 1. (400 aa)
TCF7L1Transcription factor 7 like 1. (490 aa)
CD14Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (371 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
CEBPACCAAT/enhancer-binding protein. (268 aa)
CEBPECCAAT/enhancer-binding protein. (281 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
KITKIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (948 aa)
CSDE1Cold shock domain containing E1. (784 aa)
M3Y2Z6_MUSPFUncharacterized protein. (189 aa)
M3Y2L0_MUSPFFc of IgG, high affinity Ia, receptor. (352 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1281 aa)
M3Y027_MUSPFProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
SPI1Spi-1 proto-oncogene. (257 aa)
ZBTB16Zinc finger and BTB domain containing 16. (673 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (479 aa)
PPARDPeroxisome proliferator activated receptor delta. (366 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (715 aa)
MAPK1Mitogen-activated protein kinase. (333 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
M3XSG3_MUSPFCTNNB1_binding domain-containing protein. (169 aa)
TCF7L2Transcription factor 7 like 2. (514 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (421 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
MYCV-myc myelocytomatosis viral oncoprotein-like protein. (453 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
PER2Period circadian regulator 2. (1278 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (432 aa)
PMLPromyelocytic leukemia. (876 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (644 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2552 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
M3YWA8_MUSPFUncharacterized protein. (726 aa)
BCL2A1BCL2 related protein A1. (174 aa)
MPOMyeloperoxidase. (719 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
RARARetinoic acid receptor, alpha. (462 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
PIM1Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (313 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (978 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
PIM2Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (370 aa)
ARAFV-raf murine sarcoma 3611 viral oncoprotein-like protein. (606 aa)
PPP1R14BProtein phosphatase 1 regulatory inhibitor subunit 14B. (145 aa)
M3YNJ8_MUSPFUncharacterized protein. (461 aa)
BADBCL2 associated agonist of cell death. (168 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (399 aa)
RELARELA proto-oncogene, NF-kB subunit. (511 aa)
M3YJF2_MUSPFUncharacterized protein. (140 aa)
CSF2Colony stimulating factor 2. (148 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1053 aa)
JUPJunction plakoglobin. (744 aa)
M3YH29_MUSPFUncharacterized protein. (180 aa)
STAT5BSignal transducer and activator of transcription. (691 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1276 aa)
KRASKRAS proto-oncogene, GTPase. (208 aa)
TCF7Transcription factor 7. (339 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E binding protein 1. (118 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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