STRINGSTRING
SHLD2 SHLD2 SOX11 SOX11 PIK3IP1 PIK3IP1 GH1 GH1 SDC1 SDC1 ITGA11 ITGA11 MAPRE1 MAPRE1 PLD2 PLD2 KLRAP1 KLRAP1 SLAIN2 SLAIN2 CENPI CENPI NIFK NIFK CHAC1 CHAC1 EML4 EML4 NCKIPSD NCKIPSD IKZF3 IKZF3 NPM1 NPM1 ENTHD1 ENTHD1 IL6 IL6 CENPK CENPK SLX4IP SLX4IP DOCK10 DOCK10 YBEY YBEY MAPRE3 MAPRE3 TNFRSF8 TNFRSF8 TOM1 TOM1 OSM OSM DCTN1 DCTN1 PLD1 PLD1 REV3L REV3L HELQ HELQ DOCK11 DOCK11 FADD FADD CD22 CD22 IZUMO4 IZUMO4 CLASRP CLASRP CLIP1 CLIP1 TNF TNF DOCK9 DOCK9 HBM HBM CADM1 CADM1 CLASP1 CLASP1 TPPP TPPP COG2 COG2 TSPEAR TSPEAR LOC101097290 LOC101097290 ENSFCAP00000060460 ENSFCAP00000060460
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SHLD2Shieldin complex subunit 2. (1045 aa)
SOX11Transcription factor SOX. (412 aa)
PIK3IP1Phosphoinositide-3-kinase interacting protein 1. (311 aa)
GH1Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues; Belongs to the somatotropin/prolactin family. (246 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (310 aa)
ITGA11Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1189 aa)
MAPRE1Microtubule associated protein RP/EB family member 1. (268 aa)
PLD2Phospholipase. (984 aa)
KLRAP1Uncharacterized protein. (273 aa)
SLAIN2SLAIN motif family member 2. (608 aa)
CENPICentromere protein I. (791 aa)
NIFKNucleolar protein interacting with the FHA domain of MKI67. (292 aa)
CHAC1Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (222 aa)
EML4EMAP like 4. (1006 aa)
NCKIPSDNCK interacting protein with SH3 domain. (721 aa)
IKZF3IKAROS family zinc finger 3. (509 aa)
NPM1Nucleophosmin 1. (294 aa)
ENTHD1ENTH domain containing 1. (611 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (233 aa)
CENPKCentromere protein K. (292 aa)
SLX4IPSLX4 interacting protein. (406 aa)
DOCK10Dedicator of cytokinesis 10; Belongs to the DOCK family. (2220 aa)
YBEYUncharacterized protein. (345 aa)
MAPRE3Microtubule associated protein RP/EB family member 3. (281 aa)
TNFRSF8TNF receptor superfamily member 8. (593 aa)
TOM1Target of myb1 membrane trafficking protein; Belongs to the TOM1 family. (510 aa)
OSMOncostatin M. (238 aa)
DCTN1CAP-Gly domain-containing protein. (1279 aa)
PLD1Phospholipase. (1074 aa)
REV3LREV3 like, DNA directed polymerase zeta catalytic subunit. (3131 aa)
HELQHelicase, POLQ like. (1063 aa)
DOCK11Dedicator of cytokinesis 11; Belongs to the DOCK family. (2078 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (215 aa)
CD22CD22 molecule. (845 aa)
IZUMO4IZUMO family member 4. (229 aa)
CLASRPCLK4 associating serine/arginine rich protein. (678 aa)
CLIP1CAP-Gly domain containing linker protein 1. (1438 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (321 aa)
DOCK9Dedicator of cytokinesis 9; Belongs to the DOCK family. (2132 aa)
HBMHemoglobin subunit mu; Belongs to the globin family. (141 aa)
CADM1Cell adhesion molecule 1. (593 aa)
CLASP1Cytoplasmic linker associated protein 1. (1597 aa)
TPPPTubulin polymerization promoting protein. (295 aa)
COG2Component of oligomeric golgi complex 2. (761 aa)
TSPEARThrombospondin type laminin G domain and EAR repeats. (678 aa)
LOC101097290GLOBIN domain-containing protein; Belongs to the globin family. (189 aa)
ENSFCAP00000060460Ly49 domain-containing protein. (157 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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