21 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C1QTNF3	C1q domain-containing protein. (319 aa)
	AZIN2	Antizyme inhibitor 2; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (549 aa)
	ANKRD42	Ankyrin repeat domain 42. (551 aa)
	TAF13	TATA-box binding protein associated factor 13. (124 aa)
	RBM4B	RNA binding motif protein 4B. (359 aa)
	ENSFCAP00000036463	Uncharacterized protein; Belongs to the synuclein family. (137 aa)
	TH	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (557 aa)
	PRKN	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (462 aa)
	NOTO	Notochord homeobox. (241 aa)
	RASGEF1A	RasGEF domain family member 1A. (488 aa)
	ENSFCAP00000051761	Uncharacterized protein. (189 aa)
	PPP1R1B	Protein phosphatase 1 regulatory inhibitor subunit 1B. (209 aa)
	PINK1	PTEN induced kinase 1. (581 aa)
	GFRA3	GDNF family receptor alpha 3. (395 aa)
	LRRK2	Leucine rich repeat kinase 2. (2527 aa)
	SPRY2	Sprouty RTK signaling antagonist 2. (315 aa)
	CHRNB3	Cholinergic receptor nicotinic beta 3 subunit. (466 aa)
	COX10	Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family. (444 aa)
	PARK7	Parkinsonism associated deglycase. (189 aa)
	KCTD18	Potassium channel tetramerization domain containing 18. (417 aa)
	SNCA	Alpha-synuclein; Belongs to the synuclein family. (140 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFCAP00000036463	LRRK2	ENSFCAP00000036463	ENSFCAP00000001684	Uncharacterized protein; Belongs to the synuclein family.	Leucine rich repeat kinase 2.	0.543
ENSFCAP00000036463	PARK7	ENSFCAP00000036463	ENSFCAP00000019507	Uncharacterized protein; Belongs to the synuclein family.	Parkinsonism associated deglycase.	0.748
ENSFCAP00000036463	PINK1	ENSFCAP00000036463	ENSFCAP00000000737	Uncharacterized protein; Belongs to the synuclein family.	PTEN induced kinase 1.	0.585
ENSFCAP00000036463	PRKN	ENSFCAP00000036463	ENSFCAP00000043123	Uncharacterized protein; Belongs to the synuclein family.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.	0.771
ENSFCAP00000036463	TH	ENSFCAP00000036463	ENSFCAP00000040242	Uncharacterized protein; Belongs to the synuclein family.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.493
LRRK2	ENSFCAP00000036463	ENSFCAP00000001684	ENSFCAP00000036463	Leucine rich repeat kinase 2.	Uncharacterized protein; Belongs to the synuclein family.	0.543
LRRK2	PINK1	ENSFCAP00000001684	ENSFCAP00000000737	Leucine rich repeat kinase 2.	PTEN induced kinase 1.	0.505
LRRK2	PRKN	ENSFCAP00000001684	ENSFCAP00000043123	Leucine rich repeat kinase 2.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.	0.458
LRRK2	SNCA	ENSFCAP00000001684	ENSFCAP00000027235	Leucine rich repeat kinase 2.	Alpha-synuclein; Belongs to the synuclein family.	0.543
PARK7	ENSFCAP00000036463	ENSFCAP00000019507	ENSFCAP00000036463	Parkinsonism associated deglycase.	Uncharacterized protein; Belongs to the synuclein family.	0.748
PARK7	PINK1	ENSFCAP00000019507	ENSFCAP00000000737	Parkinsonism associated deglycase.	PTEN induced kinase 1.	0.904
PARK7	PRKN	ENSFCAP00000019507	ENSFCAP00000043123	Parkinsonism associated deglycase.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.	0.885
PARK7	SNCA	ENSFCAP00000019507	ENSFCAP00000027235	Parkinsonism associated deglycase.	Alpha-synuclein; Belongs to the synuclein family.	0.790
PARK7	TH	ENSFCAP00000019507	ENSFCAP00000040242	Parkinsonism associated deglycase.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.497
PINK1	ENSFCAP00000036463	ENSFCAP00000000737	ENSFCAP00000036463	PTEN induced kinase 1.	Uncharacterized protein; Belongs to the synuclein family.	0.585
PINK1	LRRK2	ENSFCAP00000000737	ENSFCAP00000001684	PTEN induced kinase 1.	Leucine rich repeat kinase 2.	0.505
PINK1	PARK7	ENSFCAP00000000737	ENSFCAP00000019507	PTEN induced kinase 1.	Parkinsonism associated deglycase.	0.904
PINK1	PRKN	ENSFCAP00000000737	ENSFCAP00000043123	PTEN induced kinase 1.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.	0.999
PINK1	SNCA	ENSFCAP00000000737	ENSFCAP00000027235	PTEN induced kinase 1.	Alpha-synuclein; Belongs to the synuclein family.	0.816
PINK1	TH	ENSFCAP00000000737	ENSFCAP00000040242	PTEN induced kinase 1.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.564