STRINGSTRING
UQCRC2 UQCRC2 ENSFCAP00000029907 ENSFCAP00000029907 SPTAN1 SPTAN1 ALB ALB ENSFCAP00000027525 ENSFCAP00000027525 ENSFCAP00000027328 ENSFCAP00000027328 ENSFCAP00000025816 ENSFCAP00000025816 GOT2 GOT2 M3XE36_FELCA M3XE36_FELCA VCL VCL TPI1 TPI1 LOC101100947 LOC101100947 M3X4Q0_FELCA M3X4Q0_FELCA PGK2 PGK2 IDH2 IDH2 ATP5F1A ATP5F1A PARP6 PARP6 HSPD1 HSPD1 ATP5PO ATP5PO LOC101081229 LOC101081229 ACO2 ACO2 HADHB HADHB HADHA HADHA ALDOA ALDOA PFKM PFKM PGK1 PGK1 PDHA1 PDHA1 ATP5F1B ATP5F1B CS CS CSRP3 CSRP3 IDH3A IDH3A MYH6 MYH6 PYGB PYGB PDHA2 PDHA2 ENSFCAP00000033387 ENSFCAP00000033387 SLC25A5 SLC25A5 GAPDH GAPDH CKMT2 CKMT2 NNT NNT CKM CKM MYBPC3 MYBPC3 HSPA9 HSPA9 MYOM1 MYOM1 FLNC FLNC MDH2 MDH2 HADH HADH TF TF ENSFCAP00000060491 ENSFCAP00000060491 ACAT1 ACAT1 MYL2 MYL2 ANXA6 ANXA6 LOC111558717 LOC111558717 ENSFCAP00000053301 ENSFCAP00000053301 OGDH OGDH ENSFCAP00000048834 ENSFCAP00000048834 SLC25A6 SLC25A6 ACAA2 ACAA2 SRL SRL PKM PKM MB MB ENSFCAP00000040280 ENSFCAP00000040280 DYRK4 DYRK4 ENSFCAP00000039745 ENSFCAP00000039745 HSPA8 HSPA8 OGDHL OGDHL LOC101098213 LOC101098213 SLC25A4 SLC25A4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UQCRC2Ubiquinol-cytochrome c reductase core protein 2; Belongs to the peptidase M16 family. (453 aa)
ENSFCAP00000029907Phosphoglycerate kinase. (246 aa)
SPTAN1Spectrin alpha, non-erythrocytic 1. (2725 aa)
ALBSerum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] (618 aa)
ENSFCAP00000027525Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ENSFCAP00000027328Cytochrome c domain-containing protein; Belongs to the cytochrome c family. (103 aa)
ENSFCAP00000025816Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (145 aa)
GOT2Aspartate aminotransferase. (430 aa)
M3XE36_FELCAUncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (243 aa)
VCLVinculin. (1066 aa)
TPI1Triosephosphate isomerase. (286 aa)
LOC101100947Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
M3X4Q0_FELCAGp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (215 aa)
PGK2Phosphoglycerate kinase. (417 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (451 aa)
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (553 aa)
PARP6Poly [ADP-ribose] polymerase. (630 aa)
HSPD1Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family. (573 aa)
ATP5POUncharacterized protein. (213 aa)
LOC101081229Pyruvate kinase; Belongs to the pyruvate kinase family. (353 aa)
ACO2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (781 aa)
HADHBHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family. (475 aa)
HADHAHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa)
ALDOAFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (469 aa)
PFKMATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (859 aa)
PGK1Phosphoglycerate kinase. (454 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (397 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (528 aa)
CSCitrate synthase; Belongs to the citrate synthase family. (466 aa)
CSRP3Cysteine and glycine rich protein 3. (271 aa)
IDH3AIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa)
MYH6Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1939 aa)
PYGBAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (843 aa)
PDHA2Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (391 aa)
ENSFCAP00000033387Uncharacterized protein. (491 aa)
SLC25A5Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (333 aa)
CKMT2Creatine kinase, mitochondrial 2; Belongs to the ATP:guanido phosphotransferase family. (443 aa)
NNTNicotinamide nucleotide transhydrogenase. (1088 aa)
CKMCreatine kinase, M-type; Belongs to the ATP:guanido phosphotransferase family. (424 aa)
MYBPC3Myosin binding protein C, cardiac. (1273 aa)
HSPA9Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (679 aa)
MYOM1Myomesin 1. (1658 aa)
FLNCFilamin C. (2719 aa)
MDH2Malate dehydrogenase, mitochondrial; Belongs to the LDH/MDH superfamily. MDH type 1 family. (338 aa)
HADHHydroxyacyl-CoA dehydrogenase. (338 aa)
TFTransferrin; Belongs to the transferrin family. (706 aa)
ENSFCAP00000060491Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (308 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (517 aa)
MYL2Myosin light chain 2. (174 aa)
ANXA6Annexin. (723 aa)
LOC111558717Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (317 aa)
ENSFCAP00000053301Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (133 aa)
OGDHOxoglutarate dehydrogenase. (1038 aa)
ENSFCAP00000048834Uncharacterized protein. (139 aa)
SLC25A6Solute carrier family 25 member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family. (318 aa)
ACAA2Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
SRLSarcalumenin; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (830 aa)
PKMPyruvate kinase PKM; Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP (By similarity). Stimulates POU5F1-mediated transcriptional activation (By similarity). Promotes in a STAT1-dependent manner, the expression of the immune checkpoint protein CD274 in ARNTL/BMAL1-deficient macrophages (By similarity). (531 aa)
MBMyoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. (154 aa)
ENSFCAP00000040280Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (127 aa)
DYRK4Dual specificity tyrosine phosphorylation regulated kinase 4. (637 aa)
ENSFCAP00000039745Uncharacterized protein. (55 aa)
HSPA8Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family. (667 aa)
OGDHLOxoglutarate dehydrogenase like. (1006 aa)
LOC101098213Cytochrome c. (105 aa)
SLC25A4Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.