STRINGSTRING
SPTAN1 SPTAN1 HADH HADH TF TF ENSFCAP00000060491 ENSFCAP00000060491 ANXA6 ANXA6 LOC111558717 LOC111558717 RYR2 RYR2 ENSFCAP00000053301 ENSFCAP00000053301 VIM VIM OGDH OGDH ENSFCAP00000048834 ENSFCAP00000048834 MYBPC3 MYBPC3 MDH2 MDH2 GJA5 GJA5 ENSFCAP00000029907 ENSFCAP00000029907 MYL7 MYL7 CKM CKM SLC25A6 SLC25A6 DES DES SHOX2 SHOX2 TBX15 TBX15 MB MB SHOX SHOX TBX18 TBX18 ENSFCAP00000040280 ENSFCAP00000040280 ENSFCAP00000039745 ENSFCAP00000039745 HSPA8 HSPA8 LOC101098213 LOC101098213 SLC25A4 SLC25A4 ENSFCAP00000033387 ENSFCAP00000033387 NECAB1 NECAB1 NNT NNT NECAB3 NECAB3 HCN4 HCN4 KCNK7 KCNK7 GAPDH GAPDH SLC25A5 SLC25A5 MYH6 MYH6 ATP5F1B ATP5F1B PYGM PYGM PGK1 PGK1 ALDOA ALDOA ACO2 ACO2 HCN2 HCN2 ATP5PO ATP5PO HSPD1 HSPD1 ATP5F1A ATP5F1A IDH2 IDH2 PGK2 PGK2 M3X4Q0_FELCA M3X4Q0_FELCA LOC101100947 LOC101100947 HCN1 HCN1 VCL VCL M3XE36_FELCA M3XE36_FELCA ENSFCAP00000025816 ENSFCAP00000025816 GJC1 GJC1 ENSFCAP00000027328 ENSFCAP00000027328 ENSFCAP00000027525 ENSFCAP00000027525 LDB3 LDB3 ALB ALB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SPTAN1Spectrin alpha, non-erythrocytic 1. (2725 aa)
HADHHydroxyacyl-CoA dehydrogenase. (338 aa)
TFTransferrin; Belongs to the transferrin family. (706 aa)
ENSFCAP00000060491Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (308 aa)
ANXA6Annexin. (723 aa)
LOC111558717Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (317 aa)
RYR2Ryanodine receptor 2. (4967 aa)
ENSFCAP00000053301Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (133 aa)
VIMVimentin; Belongs to the intermediate filament family. (466 aa)
OGDHOxoglutarate dehydrogenase. (1038 aa)
ENSFCAP00000048834Uncharacterized protein. (139 aa)
MYBPC3Myosin binding protein C, cardiac. (1273 aa)
MDH2Malate dehydrogenase, mitochondrial; Belongs to the LDH/MDH superfamily. MDH type 1 family. (338 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
ENSFCAP00000029907Phosphoglycerate kinase. (246 aa)
MYL7Myosin light chain 7. (216 aa)
CKMCreatine kinase, M-type; Belongs to the ATP:guanido phosphotransferase family. (424 aa)
SLC25A6Solute carrier family 25 member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family. (318 aa)
DESDesmin; Belongs to the intermediate filament family. (514 aa)
SHOX2Uncharacterized protein. (321 aa)
TBX15T-box transcription factor 15. (602 aa)
MBMyoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. (154 aa)
SHOXShort stature homeobox. (320 aa)
TBX18T-box transcription factor 18. (775 aa)
ENSFCAP00000040280Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (127 aa)
ENSFCAP00000039745Uncharacterized protein. (55 aa)
HSPA8Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family. (667 aa)
LOC101098213Cytochrome c. (105 aa)
SLC25A4Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
ENSFCAP00000033387Uncharacterized protein. (491 aa)
NECAB1N-terminal EF-hand calcium binding protein 1. (429 aa)
NNTNicotinamide nucleotide transhydrogenase. (1088 aa)
NECAB3N-terminal EF-hand calcium binding protein 3. (371 aa)
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1202 aa)
KCNK7Potassium two pore domain channel subfamily K member 7; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (307 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (333 aa)
SLC25A5Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
MYH6Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1939 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (528 aa)
PYGMAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (842 aa)
PGK1Phosphoglycerate kinase. (454 aa)
ALDOAFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (469 aa)
ACO2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (781 aa)
HCN2Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (895 aa)
ATP5POUncharacterized protein. (213 aa)
HSPD1Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family. (573 aa)
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (553 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (451 aa)
PGK2Phosphoglycerate kinase. (417 aa)
M3X4Q0_FELCAGp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (215 aa)
LOC101100947Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
HCN1Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (882 aa)
VCLVinculin. (1066 aa)
M3XE36_FELCAUncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (243 aa)
ENSFCAP00000025816Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (145 aa)
GJC1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (396 aa)
ENSFCAP00000027328Cytochrome c domain-containing protein; Belongs to the cytochrome c family. (103 aa)
ENSFCAP00000027525Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LDB3LIM domain binding 3. (723 aa)
ALBSerum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] (618 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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