27 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FSTL1	Follistatin like 1. (328 aa)
	PLXND1	Plexin D1. (1927 aa)
	ADAMDEC1	ADAM like decysin 1. (470 aa)
	CD4	CD4 molecule. (487 aa)
	LAMB1	Laminin subunit beta 1. (1786 aa)
	SERPINF2	Serpin family F member 2; Belongs to the serpin family. (565 aa)
	MERTK	MER proto-oncogene, tyrosine kinase. (994 aa)
	IL6ST	Interleukin 6 signal transducer. (918 aa)
	TFPI	Tissue factor pathway inhibitor. (331 aa)
	BST1	Bone marrow stromal cell antigen 1. (313 aa)
	ICAM3	Intercellular adhesion molecule 3. (552 aa)
	CLEC12A	C-type lectin domain family 12 member A. (271 aa)
	IL6	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (233 aa)
	APOD	Apolipoprotein D. (189 aa)
	M3XGE2_FELCA	Uncharacterized protein. (87 aa)
	F13A1	Coagulation factor XIII A chain. (787 aa)
	MST1	Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (725 aa)
	MRTFA	Myocardin related transcription factor A. (1061 aa)
	MLLT10	MLLT10 histone lysine methyltransferase DOT1L cofactor. (1147 aa)
	LRG1	Leucine rich alpha-2-glycoprotein 1. (346 aa)
	LOC101090265	Ig-like domain-containing protein. (263 aa)
	A1BG	Alpha-1-B glycoprotein. (542 aa)
	THPO	Thrombopoietin. (409 aa)
	F8	Coagulation factor VIII; Belongs to the multicopper oxidase family. (2337 aa)
	PAMR1	Peptidase domain containing associated with muscle regeneration 1; Belongs to the peptidase S1 family. (1060 aa)
	APOH	Apolipoprotein H. (382 aa)
	LOC111556173	Ig-like domain-containing protein. (308 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A1BG	APOD	ENSFCAP00000051884	ENSFCAP00000022999	Alpha-1-B glycoprotein.	Apolipoprotein D.	0.480
A1BG	APOH	ENSFCAP00000051884	ENSFCAP00000058764	Alpha-1-B glycoprotein.	Apolipoprotein H.	0.519
APOD	A1BG	ENSFCAP00000022999	ENSFCAP00000051884	Apolipoprotein D.	Alpha-1-B glycoprotein.	0.480
APOD	APOH	ENSFCAP00000022999	ENSFCAP00000058764	Apolipoprotein D.	Apolipoprotein H.	0.659
APOH	A1BG	ENSFCAP00000058764	ENSFCAP00000051884	Apolipoprotein H.	Alpha-1-B glycoprotein.	0.519
APOH	APOD	ENSFCAP00000058764	ENSFCAP00000022999	Apolipoprotein H.	Apolipoprotein D.	0.659
APOH	SERPINF2	ENSFCAP00000058764	ENSFCAP00000005854	Apolipoprotein H.	Serpin family F member 2; Belongs to the serpin family.	0.639
CD4	ICAM3	ENSFCAP00000003936	ENSFCAP00000019585	CD4 molecule.	Intercellular adhesion molecule 3.	0.449
CD4	IL6	ENSFCAP00000003936	ENSFCAP00000022423	CD4 molecule.	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...]	0.927
CD4	LOC101090265	ENSFCAP00000003936	ENSFCAP00000041201	CD4 molecule.	Ig-like domain-containing protein.	0.919
CD4	MERTK	ENSFCAP00000003936	ENSFCAP00000007493	CD4 molecule.	MER proto-oncogene, tyrosine kinase.	0.435
ICAM3	CD4	ENSFCAP00000019585	ENSFCAP00000003936	Intercellular adhesion molecule 3.	CD4 molecule.	0.449
IL6	CD4	ENSFCAP00000022423	ENSFCAP00000003936	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...]	CD4 molecule.	0.927
IL6	IL6ST	ENSFCAP00000022423	ENSFCAP00000010090	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...]	Interleukin 6 signal transducer.	0.962
IL6	THPO	ENSFCAP00000022423	ENSFCAP00000053329	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...]	Thrombopoietin.	0.610
IL6ST	IL6	ENSFCAP00000010090	ENSFCAP00000022423	Interleukin 6 signal transducer.	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...]	0.962
LOC101090265	CD4	ENSFCAP00000041201	ENSFCAP00000003936	Ig-like domain-containing protein.	CD4 molecule.	0.919
LOC101090265	LOC111556173	ENSFCAP00000041201	ENSFCAP00000059830	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.543
LOC111556173	LOC101090265	ENSFCAP00000059830	ENSFCAP00000041201	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.543
LRG1	MST1	ENSFCAP00000040524	ENSFCAP00000029539	Leucine rich alpha-2-glycoprotein 1.	Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily.	0.445