STRINGSTRING
ARPC2 ARPC2 ARPC3 ARPC3 CTTN CTTN WASF2 WASF2 WHAMM WHAMM WASF3 WASF3 BRK1 BRK1 ABI2 ABI2 CYFIP1 CYFIP1 ACTR3 ACTR3 ARPC1A ARPC1A HCLS1 HCLS1 ARPC5 ARPC5 WAS WAS ABI3 ABI3 WASF1 WASF1 NCKIPSD NCKIPSD M3WS97_FELCA M3WS97_FELCA ARPC4 ARPC4 ABI1 ABI1 ARPC5L ARPC5L LOC101100956 LOC101100956 WASL WASL NCKAP1 NCKAP1 ENSFCAP00000032522 ENSFCAP00000032522 ACTR2 ACTR2 ENSFCAP00000035896 ENSFCAP00000035896 ENSFCAP00000041826 ENSFCAP00000041826 NCKAP1L NCKAP1L BAIAP2 BAIAP2 ENSFCAP00000043946 ENSFCAP00000043946 CYFIP2 CYFIP2 ACTR3B ACTR3B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (300 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
CTTNCortactin. (538 aa)
WASF2WASP family member 2. (498 aa)
WHAMMWASP homolog associated with actin, golgi membranes and microtubules. (745 aa)
WASF3WASP family member 3. (502 aa)
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (75 aa)
ABI2Abl interactor 2. (542 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
ACTR3Actin related protein 3; Belongs to the actin family. (418 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (397 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (494 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
WASWASP actin nucleation promoting factor. (501 aa)
ABI3ABI family member 3. (365 aa)
WASF1WASP family member 1. (570 aa)
NCKIPSDNCK interacting protein with SH3 domain. (721 aa)
M3WS97_FELCAArp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (151 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (187 aa)
ABI1Abl interactor 1. (508 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
LOC101100956Uncharacterized protein. (129 aa)
WASLWASP like actin nucleation promoting factor. (505 aa)
NCKAP1NCK associated protein 1. (1134 aa)
ENSFCAP00000032522Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (132 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
ENSFCAP00000035896Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (140 aa)
ENSFCAP00000041826Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
NCKAP1LNCK associated protein 1 like. (1179 aa)
BAIAP2BAI1 associated protein 2. (548 aa)
ENSFCAP00000043946Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (118 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1335 aa)
ACTR3BUncharacterized protein; Belongs to the actin family. (522 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.