STRINGSTRING
DRAXIN DRAXIN RND1 RND1 PLXND1 PLXND1 CHCHD6 CHCHD6 IRGC IRGC PLXNB1 PLXNB1 PDCD5 PDCD5 SLIT1 SLIT1 FARP2 FARP2 SEMA4D SEMA4D ADGRL3 ADGRL3 NRP1 NRP1 KIRREL2 KIRREL2 ROBO3 ROBO3 ROBO4 ROBO4 SEMA3F SEMA3F EPHA1 EPHA1 EPHA4 EPHA4 SEMA7A SEMA7A TENM1 TENM1 EPHB3 EPHB3 EPHA2 EPHA2 SLIT3 SLIT3 IGDCC4 IGDCC4 PLXNB2 PLXNB2 TLN1 TLN1 DCC DCC TGM3 TGM3 ROBO1 ROBO1 EPHB6 EPHB6 EFNB2 EFNB2 NELL2 NELL2 EPHA7 EPHA7 LRRC4C LRRC4C SEMA3E SEMA3E SEMA3C SEMA3C TESK1 TESK1 FLRT2 FLRT2 EPHA8 EPHA8 TENM3 TENM3 NTN5 NTN5 SEMA3A SEMA3A UNC5B UNC5B SEMA6A SEMA6A TENM2 TENM2 SPICE1 SPICE1 UNC5A UNC5A EPHA3 EPHA3 EPHA10 EPHA10 EPHB2 EPHB2 ARVCF ARVCF ADGRL2 ADGRL2 PLXNC1 PLXNC1 SEMA6D SEMA6D NEO1 NEO1 PLXNA2 PLXNA2 EPHA5 EPHA5 UNC5C UNC5C EPHB4 EPHB4 DCLK1 DCLK1 SLIT2 SLIT2 EFNA5 EFNA5 EPHB1 EPHB1 DSCAML1 DSCAML1 PTPRO PTPRO ROBO2 ROBO2 EFNA4 EFNA4 NGEF NGEF SEMA6C SEMA6C NTN4 NTN4 PIP5K1C PIP5K1C RHOD RHOD TENM4 TENM4 EFNB3 EFNB3 RGMB RGMB EFNA2 EFNA2 NRP2 NRP2 EPHA6 EPHA6 UNC5D UNC5D ENSFCAP00000050553 ENSFCAP00000050553 SEMA4C SEMA4C EFNA3 EFNA3 PLXNA4 PLXNA4 SLITRK2 SLITRK2 NTN3 NTN3 SEMA4A SEMA4A TMEM18 TMEM18 FES FES ADGRL1 ADGRL1 DSCAM DSCAM ENSFCAP00000054276 ENSFCAP00000054276 RGMA RGMA PLXNB3 PLXNB3 FLRT3 FLRT3 NTN1 NTN1 EFNA1 EFNA1 ENSFCAP00000060568 ENSFCAP00000060568 SEMA3B SEMA3B SEMA6B SEMA6B NTNG1 NTNG1 EFNB1 EFNB1 PLXNA3 PLXNA3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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DRAXINDraxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (377 aa)
RND1Rho family GTPase 1. (232 aa)
PLXND1Plexin D1. (1927 aa)
CHCHD6MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (2112 aa)
IRGCImmunity related GTPase cinema. (435 aa)
PLXNB1Plexin B1. (2135 aa)
PDCD5Programmed cell death 5. (197 aa)
SLIT1Slit guidance ligand 1. (1518 aa)
FARP2FERM, ARH/RhoGEF and pleckstrin domain protein 2. (1112 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (863 aa)
ADGRL3Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family. (1580 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
KIRREL2Kirre like nephrin family adhesion molecule 2. (861 aa)
ROBO3Roundabout guidance receptor 3. (1383 aa)
ROBO4Roundabout guidance receptor 4. (1007 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (785 aa)
EPHA1EPH receptor A1. (976 aa)
EPHA4EPH receptor A4. (986 aa)
SEMA7ASemaphorin 7A; Belongs to the semaphorin family. (769 aa)
TENM1Teneurin transmembrane protein 1. (2732 aa)
EPHB3EPH receptor B3. (1000 aa)
EPHA2EPH receptor A2. (936 aa)
SLIT3Slit guidance ligand 3. (1530 aa)
IGDCC4Immunoglobulin superfamily DCC subclass member 4. (1249 aa)
PLXNB2Plexin B2. (1841 aa)
TLN1Talin 1. (2558 aa)
DCCDCC netrin 1 receptor. (1446 aa)
TGM3TGc domain-containing protein. (744 aa)
ROBO1Roundabout guidance receptor 1. (1550 aa)
EPHB6EPH receptor B6. (1012 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (333 aa)
NELL2Neural EGFL like 2. (816 aa)
EPHA7EPH receptor A7. (1000 aa)
LRRC4CLeucine rich repeat containing 4C. (640 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (775 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (749 aa)
TESK1Testis associated actin remodelling kinase 1. (628 aa)
FLRT2Fibronectin leucine rich transmembrane protein 2. (630 aa)
EPHA8EPH receptor A8. (1003 aa)
TENM3Teneurin transmembrane protein 3. (2699 aa)
NTN5Netrin 5. (489 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (773 aa)
UNC5BUnc-5 netrin receptor B. (945 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1047 aa)
TENM2Teneurin transmembrane protein 2. (2774 aa)
SPICE1Uncharacterized protein. (862 aa)
UNC5AUnc-5 netrin receptor A. (898 aa)
EPHA3EPH receptor A3. (984 aa)
EPHA10EPH receptor A10. (1008 aa)
EPHB2EPH receptor B2. (899 aa)
ARVCFARVCF delta catenin family member. (965 aa)
ADGRL2Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family. (1492 aa)
PLXNC1Plexin C1. (1576 aa)
SEMA6DSemaphorin 6D; Belongs to the semaphorin family. (1069 aa)
NEO1Neogenin 1. (1480 aa)
PLXNA2Plexin A2. (1911 aa)
EPHA5EPH receptor A5. (1043 aa)
UNC5CUnc-5 netrin receptor C. (931 aa)
EPHB4EPH receptor B4. (987 aa)
DCLK1Doublecortin like kinase 1. (741 aa)
SLIT2Slit guidance ligand 2. (1543 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (228 aa)
EPHB1EPH receptor B1. (984 aa)
DSCAML1DS cell adhesion molecule like 1. (2112 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1216 aa)
ROBO2Roundabout guidance receptor 2. (1439 aa)
EFNA4Ephrin RBD domain-containing protein; Belongs to the ephrin family. (314 aa)
NGEFNeuronal guanine nucleotide exchange factor. (707 aa)
SEMA6CSemaphorin 6C; Belongs to the semaphorin family. (1023 aa)
NTN4Netrin 4. (628 aa)
PIP5K1CPhosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (818 aa)
RHODRas homolog family member D. (210 aa)
TENM4Teneurin transmembrane protein 4. (2823 aa)
EFNB3Ephrin RBD domain-containing protein; Belongs to the ephrin family. (340 aa)
RGMBRepulsive guidance molecule BMP co-receptor b. (482 aa)
EFNA2Ephrin A2; Belongs to the ephrin family. (263 aa)
NRP2Neuropilin 2. (992 aa)
EPHA6EPH receptor A6. (1169 aa)
UNC5DUnc-5 netrin receptor D. (958 aa)
ENSFCAP00000050553Uncharacterized protein. (71 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (1000 aa)
EFNA3Ephrin RBD domain-containing protein; Belongs to the ephrin family. (237 aa)
PLXNA4Plexin A4. (1893 aa)
SLITRK2Uncharacterized protein. (535 aa)
NTN3Netrin 3. (607 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (806 aa)
TMEM18Transmembrane protein 18. (154 aa)
FESTyrosine-protein kinase Fes/Fps; Tyrosine-protein kinase that acts downstream of cell surface receptors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, cell attachment and cell spreading. Plays a role in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Acts down-stream of the activated FCER1 receptor and the mast/stem cell growth factor receptor KIT. Plays a role in the regulation of mast cell degranulation. Plays a role in the regulation of cell differentiation and promotes neurite outgrowth in response to NGF [...] (861 aa)
ADGRL1Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family. (1473 aa)
DSCAMDS cell adhesion molecule. (2012 aa)
ENSFCAP00000054276Uncharacterized protein. (85 aa)
RGMARepulsive guidance molecule BMP co-receptor a. (504 aa)
PLXNB3Plexin B3. (2058 aa)
FLRT3Fibronectin leucine rich transmembrane protein 3. (649 aa)
NTN1Netrin 1. (715 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (357 aa)
ENSFCAP00000060568Uncharacterized protein. (308 aa)
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (777 aa)
SEMA6BSemaphorin 6B; Belongs to the semaphorin family. (1296 aa)
NTNG1Netrin G1. (581 aa)
EFNB1Ephrin B1. (427 aa)
PLXNA3Plexin A3. (1872 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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