(10 nodes) Hrd1p ubiquitin ligase ERAD-L complex, and Protein OS-9-like network (Felis catus)

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second shell of interactors

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proteins of unknown 3D structure

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Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	SEL1L2	SEL1L2 adaptor subunit of ERAD E3 ligase. (685 aa)
	AMFR	Autocrine motility factor receptor. (781 aa)
	SEL1L	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase. (795 aa)
	ERLEC1	Endoplasmic reticulum lectin 1. (483 aa)
	OS9	OS9 endoplasmic reticulum lectin. (668 aa)
	SPATA5L1	Spermatogenesis associated 5 like 1. (767 aa)
	DERL2	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
	DERL1	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (251 aa)
	SYVN1	Synoviolin 1. (612 aa)
	DERL3	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (245 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMFR	DERL1	ENSFCAP00000008034	ENSFCAP00000023495	Autocrine motility factor receptor.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.996
AMFR	DERL2	ENSFCAP00000008034	ENSFCAP00000023002	Autocrine motility factor receptor.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.943
AMFR	DERL3	ENSFCAP00000008034	ENSFCAP00000042029	Autocrine motility factor receptor.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.847
AMFR	ERLEC1	ENSFCAP00000008034	ENSFCAP00000012391	Autocrine motility factor receptor.	Endoplasmic reticulum lectin 1.	0.846
AMFR	OS9	ENSFCAP00000008034	ENSFCAP00000013629	Autocrine motility factor receptor.	OS9 endoplasmic reticulum lectin.	0.927
AMFR	SEL1L	ENSFCAP00000008034	ENSFCAP00000008368	Autocrine motility factor receptor.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.921
AMFR	SEL1L2	ENSFCAP00000008034	ENSFCAP00000000856	Autocrine motility factor receptor.	SEL1L2 adaptor subunit of ERAD E3 ligase.	0.797
AMFR	SPATA5L1	ENSFCAP00000008034	ENSFCAP00000016276	Autocrine motility factor receptor.	Spermatogenesis associated 5 like 1.	0.770
AMFR	SYVN1	ENSFCAP00000008034	ENSFCAP00000024842	Autocrine motility factor receptor.	Synoviolin 1.	0.697
DERL1	AMFR	ENSFCAP00000023495	ENSFCAP00000008034	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Autocrine motility factor receptor.	0.996
DERL1	DERL2	ENSFCAP00000023495	ENSFCAP00000023002	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.984
DERL1	DERL3	ENSFCAP00000023495	ENSFCAP00000042029	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.984
DERL1	ERLEC1	ENSFCAP00000023495	ENSFCAP00000012391	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Endoplasmic reticulum lectin 1.	0.949
DERL1	OS9	ENSFCAP00000023495	ENSFCAP00000013629	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	OS9 endoplasmic reticulum lectin.	0.968
DERL1	SEL1L	ENSFCAP00000023495	ENSFCAP00000008368	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.970
DERL1	SEL1L2	ENSFCAP00000023495	ENSFCAP00000000856	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	SEL1L2 adaptor subunit of ERAD E3 ligase.	0.907
DERL1	SPATA5L1	ENSFCAP00000023495	ENSFCAP00000016276	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Spermatogenesis associated 5 like 1.	0.884
DERL1	SYVN1	ENSFCAP00000023495	ENSFCAP00000024842	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Synoviolin 1.	0.982
DERL2	AMFR	ENSFCAP00000023002	ENSFCAP00000008034	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Autocrine motility factor receptor.	0.943
DERL2	DERL1	ENSFCAP00000023002	ENSFCAP00000023495	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.984