Cytokine receptor like factor 2.

Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.

Cytokine receptor like factor 2.

Interferon alpha; Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase; Belongs to the alpha/beta interferon family.

Cytokine receptor like factor 2.

Uncharacterized protein.

Cytokine receptor like factor 2.

Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.

Cytokine receptor like factor 2.

Uncharacterized protein.

Cytokine receptor like factor 2.

Uncharacterized protein.

Cytokine receptor like factor 2.

Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...]

Cytokine receptor like factor 2.

Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.

Cytokine receptor like factor 2.

Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family.

Cytokine receptor like factor 2.

Interleukin 13.

Cytokine receptor like factor 2.

Interleukin-15; Cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL15 requires interaction of IL15 with components of the IL2 receptor, including IL2RB and probably IL2RG but not IL2RA (By similarity). In neutrophils, stimulates phagocytosis probably by signaling through the IL15 receptor, composed of the subunits IL15RA, IL2RB and IL2RG, which results in kinase SYK activation (By similarity); Belongs to the IL-15/IL-21 family.

Cytokine receptor like factor 2.

Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family.

Cytokine receptor like factor 2.

Interleukin; Belongs to the IL-15/IL-21 family.

Cytokine receptor like factor 2.

Interleukin 22.

Cytokine receptor like factor 2.

Interleukin 23 subunit alpha.

Cytokine receptor like factor 2.

Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells.

Cytokine receptor like factor 2.

Interleukin 7.

Cytokine receptor like factor 2.

Interleukin 7 receptor.

Cytokine receptor like factor 2.

Interleukin 9.

Cytokine receptor like factor 2.

Tyrosine-protein kinase.