STRINGSTRING
TRAF2 TRAF2 PLEKHG5 PLEKHG5 NFKB2 NFKB2 NFKBIB NFKBIB TRAF4 TRAF4 MAP3K8 MAP3K8 NFKBIA NFKBIA TNFRSF1A TNFRSF1A NFKB1 NFKB1 REL REL NOD2 NOD2 IRAK1 IRAK1 IRAK2 IRAK2 TAB2 TAB2 TAB1 TAB1 TNIP1 TNIP1 IKBKE IKBKE MAP3K14 MAP3K14 BIRC3 BIRC3 RIPK2 RIPK2 MAP3K7 MAP3K7 IRAK4 IRAK4 CARD6 CARD6 IKBKG IKBKG BCL3 BCL3 TAB3 TAB3 RELB RELB PELI1 PELI1 TNIP2 TNIP2 TRAF5 TRAF5 TANK TANK TRAF3 TRAF3 MYD88 MYD88 NOD1 NOD1 IKBKB IKBKB TOLLIP TOLLIP TRADD TRADD TRAF6 TRAF6 RELA RELA NFKBIE NFKBIE TRAF1 TRAF1 TBK1 TBK1 TNFAIP3 TNFAIP3 CHUK CHUK IRAK3 IRAK3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa)
PLEKHG5Pleckstrin homology and RhoGEF domain containing G5. (1132 aa)
NFKB2Nuclear factor kappa B subunit 2. (921 aa)
NFKBIBNFKB inhibitor beta. (354 aa)
TRAF4TNF receptor-associated factor. (470 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (467 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
TNFRSF1ATNF receptor superfamily member 1A. (444 aa)
NFKB1Nuclear factor kappa B subunit 1. (989 aa)
RELREL proto-oncogene, NF-kB subunit. (583 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1014 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (724 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (618 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (502 aa)
TNIP1TNFAIP3 interacting protein 1. (635 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (718 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (954 aa)
BIRC3Baculoviral IAP repeat containing 3. (624 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (492 aa)
CARD6Caspase recruitment domain family member 6. (1028 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (423 aa)
BCL3BCL3 transcription coactivator. (454 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (717 aa)
RELBRELB proto-oncogene, NF-kB subunit. (582 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
TNIP2TNFAIP3 interacting protein 2. (436 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa)
TANKTRAF family member associated NFKB activator. (445 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (308 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (760 aa)
TOLLIPToll interacting protein. (306 aa)
TRADDTNFRSF1A associated via death domain. (311 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
RELARELA proto-oncogene, NF-kB subunit. (555 aa)
NFKBIENFKB inhibitor epsilon. (362 aa)
TRAF1TNF receptor-associated factor. (433 aa)
TBK1TANK binding kinase 1. (729 aa)
TNFAIP3TNF alpha induced protein 3. (804 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (774 aa)
IRAK3Interleukin 1 receptor associated kinase 3. (551 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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