STRINGSTRING
DDX58 DDX58 DHX58 DHX58 IFNB1 IFNB1 ISG20 ISG20 IRF3 IRF3 HERC5 HERC5 EIF2AK2 EIF2AK2 TRIM25 TRIM25 OASL OASL IFIT2 IFIT2 IFIH1 IFIH1 IFIT3 IFIT3 IFI44 IFI44 TLR3 TLR3 RSAD2 RSAD2 IFI6 IFI6 ISG15 ISG15 LOC101099332 LOC101099332 MAVS MAVS TICAM1 TICAM1 IRF7 IRF7 IFIT1 IFIT1 MX1 MX1 USP18 USP18
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DDX58DExD/H-box helicase 58. (929 aa)
DHX58DExH-box helicase 58. (685 aa)
IFNB1Interferon beta; Has antiviral, antibacterial and anticancer activities. (186 aa)
ISG20Interferon stimulated exonuclease gene 20. (171 aa)
IRF3Interferon regulatory factor 3. (420 aa)
HERC5HECT and RLD domain containing E3 ubiquitin protein ligase 5. (1025 aa)
EIF2AK2Eukaryotic translation initiation factor 2 alpha kinase 2. (541 aa)
TRIM25Tripartite motif containing 25. (608 aa)
OASL2'-5'-oligoadenylate synthetase like. (515 aa)
IFIT2Interferon induced protein with tetratricopeptide repeats 2. (469 aa)
IFIH1Interferon induced with helicase C domain 1. (1026 aa)
IFIT3Interferon induced protein with tetratricopeptide repeats 3. (489 aa)
IFI44Interferon induced protein 44. (433 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (917 aa)
RSAD2Radical S-adenosyl methionine domain containing 2. (363 aa)
IFI6Interferon alpha inducible protein 6. (149 aa)
ISG15ISG15 ubiquitin like modifier. (157 aa)
LOC101099332Uncharacterized protein. (520 aa)
MAVSMitochondrial antiviral signaling protein. (662 aa)
TICAM1Toll like receptor adaptor molecule 1. (815 aa)
IRF7Interferon regulatory factor 7. (512 aa)
IFIT1Interferon induced protein with tetratricopeptide repeats 1. (490 aa)
MX1MX dynamin like GTPase 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (675 aa)
USP18Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (403 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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