STRINGSTRING
PINK1 PINK1 TAPT1 TAPT1 RAB40B RAB40B WDR45B WDR45B VMP1 VMP1 ULK3 ULK3 ULK2 ULK2 RHOT2 RHOT2 ATG2B ATG2B USP35 USP35 ATG12 ATG12 USP30 USP30 GABARAPL2 GABARAPL2 CE2H16orf70 CE2H16orf70 FKBP8 FKBP8 RB1CC1 RB1CC1 ULK1 ULK1 BCL2L13 BCL2L13 ATG9A ATG9A ATG16L1 ATG16L1 MYO19 MYO19 ATG2A ATG2A BECN1 BECN1 ATG9B ATG9B ATG16L2 ATG16L2 AMBRA1 AMBRA1 ATG13 ATG13 SQSTM1 SQSTM1 ZFYVE1 ZFYVE1 ATG14 ATG14 GSAP GSAP NUPR2 NUPR2 STK35 STK35 GABARAP GABARAP M3X8L9_FELCA M3X8L9_FELCA SH3GLB1 SH3GLB1 MAP1LC3A MAP1LC3A SYBU SYBU STEAP4 STEAP4 BNIP3L BNIP3L PIK3C3 PIK3C3 FUNDC1 FUNDC1 ATG4C ATG4C MFN2 MFN2 MARCHF5 MARCHF5 STEAP3 STEAP3 OMA1 OMA1 ATG10 ATG10 NBR1 NBR1 ENSFCAP00000031232 ENSFCAP00000031232 MFN1 MFN1 LOC101095070 LOC101095070 MAP1A MAP1A RUBCN RUBCN ATG101 ATG101 ATG7 ATG7 TP53INP2 TP53INP2 MAP1LC3C MAP1LC3C PIK3R4 PIK3R4 ENSFCAP00000041779 ENSFCAP00000041779 PRKN PRKN TRAK1 TRAK1 ENSFCAP00000044926 ENSFCAP00000044926 RHOT1 RHOT1 ATG3 ATG3 ATG5 ATG5 GABARAPL1 GABARAPL1 OPA1 OPA1 BCAS3 BCAS3 ILRUN ILRUN SUPT20H SUPT20H DRAM1 DRAM1 PGAM5 PGAM5 MAP1LC3B MAP1LC3B NRBF2 NRBF2 UVRAG UVRAG MFF MFF WIPI2 WIPI2 ATG4D ATG4D ENSFCAP00000058146 ENSFCAP00000058146 WIPI1 WIPI1 ENSFCAP00000059015 ENSFCAP00000059015 ATG4B ATG4B ENSFCAP00000060319 ENSFCAP00000060319 BNIP3 BNIP3 ATG4A ATG4A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PINK1PTEN induced kinase 1. (581 aa)
TAPT1Transmembrane anterior posterior transformation 1. (780 aa)
RAB40BRAB40B, member RAS oncogene family. (279 aa)
WDR45BWD repeat domain 45B. (344 aa)
VMP1Vacuole membrane protein 1. (406 aa)
ULK3Unc-51 like kinase 3; Belongs to the protein kinase superfamily. (472 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1039 aa)
RHOT2Ras homolog family member T2. (722 aa)
ATG2BAutophagy related 2B. (2114 aa)
USP35Ubiquitin specific peptidase 35; Belongs to the peptidase C19 family. (1004 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
USP30Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (519 aa)
GABARAPL2GABA type A receptor associated protein like 2. (117 aa)
CE2H16orf70Chromosome E2 C16orf70 homolog. (422 aa)
FKBP8Peptidylprolyl isomerase. (516 aa)
RB1CC1RB1 inducible coiled-coil 1. (1593 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1113 aa)
BCL2L13BCL2 like 13. (466 aa)
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (998 aa)
ATG16L1Autophagy related 16 like 1. (623 aa)
MYO19Myosin XIX; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (974 aa)
ATG2AAutophagy related 2A. (1928 aa)
BECN1Beclin 1. (448 aa)
ATG9BAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (920 aa)
ATG16L2Autophagy related 16 like 2. (617 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1301 aa)
ATG13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (550 aa)
SQSTM1Sequestosome 1. (443 aa)
ZFYVE1Zinc finger FYVE-type containing 1. (790 aa)
ATG14Autophagy related 14. (510 aa)
GSAPGamma-secretase activating protein. (854 aa)
NUPR2Nuclear protein 2, transcriptional regulator. (103 aa)
STK35Serine/threonine kinase 35. (538 aa)
GABARAPGABA type A receptor-associated protein. (117 aa)
M3X8L9_FELCAUncharacterized protein. (306 aa)
SH3GLB1SH3 domain containing GRB2 like, endophilin B1. (401 aa)
MAP1LC3AMicrotubule associated protein 1 light chain 3 alpha. (121 aa)
SYBUSyntabulin. (662 aa)
STEAP4STEAP4 metalloreductase. (478 aa)
BNIP3LBCL2 interacting protein 3 like. (219 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
FUNDC1Uncharacterized protein. (155 aa)
ATG4CCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (458 aa)
MFN2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
MARCHF5Membrane associated ring-CH-type finger 5. (278 aa)
STEAP3STEAP3 metalloreductase. (522 aa)
OMA1OMA1 zinc metallopeptidase. (527 aa)
ATG10Autophagy related 10. (353 aa)
NBR1NBR1 autophagy cargo receptor. (968 aa)
ENSFCAP00000031232Uncharacterized protein. (108 aa)
MFN1Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (804 aa)
LOC101095070Uncharacterized protein. (141 aa)
MAP1AMicrotubule associated protein 1A. (2991 aa)
RUBCNRubicon autophagy regulator. (1014 aa)
ATG101Autophagy related 101. (344 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (752 aa)
TP53INP2Tumor protein p53 inducible nuclear protein 2. (221 aa)
MAP1LC3CUncharacterized protein. (141 aa)
PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1358 aa)
ENSFCAP00000041779Uncharacterized protein. (112 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (462 aa)
TRAK1Trafficking kinesin protein 1. (954 aa)
ENSFCAP00000044926Uncharacterized protein. (107 aa)
RHOT1Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (720 aa)
ATG3Autophagy-related protein 3. (333 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
GABARAPL1GABA type A receptor associated protein like 1. (151 aa)
OPA1OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1015 aa)
BCAS3BCAS3 microtubule associated cell migration factor. (959 aa)
ILRUNInflammation and lipid regulator with UBA-like and NBR1-like domains. (291 aa)
SUPT20HSPT20 homolog, SAGA complex component. (858 aa)
DRAM1Uncharacterized protein. (405 aa)
PGAM5Uncharacterized protein. (303 aa)
MAP1LC3BUncharacterized protein. (309 aa)
NRBF2Nuclear receptor binding factor 2. (288 aa)
UVRAGUV radiation resistance associated. (718 aa)
MFFMitochondrial fission factor. (357 aa)
WIPI2WD repeat domain, phosphoinositide interacting 2. (468 aa)
ATG4DCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (475 aa)
ENSFCAP00000058146Uncharacterized protein. (268 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (470 aa)
ENSFCAP00000059015Uncharacterized protein. (263 aa)
ATG4BCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (578 aa)
ENSFCAP00000060319Uncharacterized protein. (108 aa)
BNIP3BCL2 interacting protein 3. (187 aa)
ATG4ACysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (400 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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