STRINGSTRING
TBXT TBXT POU5F1 POU5F1 NODAL NODAL PRDM14 PRDM14 NANOG NANOG TBX10 TBX10 POU1F1 POU1F1 INHBE INHBE EOMES EOMES NANOS3 NANOS3 SMAD1 SMAD1 BMP5 BMP5 TGFB1 TGFB1 AMHR2 AMHR2 INHA INHA ZIC1 ZIC1 CHRD CHRD ACVR1 ACVR1 SOX15 SOX15 GDF3 GDF3 SNX16 SNX16 SNAI1 SNAI1 SMAD6 SMAD6 TFAP2A TFAP2A FOXA2 FOXA2 BMPR2 BMPR2 TBX19 TBX19 SMURF1 SMURF1 PTCHD4 PTCHD4 ZEB2 ZEB2 SNAI2 SNAI2 MSTN MSTN GDF11 GDF11 LOC101084379 LOC101084379 KLF4 KLF4 ZBTB16 ZBTB16 NACC1 NACC1 SMURF2 SMURF2 SKI SKI FOXH1 FOXH1 TWSG1 TWSG1 KLF17 KLF17 BMP15 BMP15 ZBED9 ZBED9 ACVR1B ACVR1B NANOS2 NANOS2 ETV5 ETV5 BMPR1A BMPR1A BMP6 BMP6 ZFYVE9 ZFYVE9 BMP10 BMP10 TWIST1 TWIST1 ZEB1 ZEB1 ACVR1C ACVR1C SOX7 SOX7 TWIST2 TWIST2 BMP2 BMP2 SMAD4 SMAD4 FST FST SMAD3 SMAD3 GBX2 GBX2 GDF5 GDF5 SALL4 SALL4 NBL1 NBL1 SKIL SKIL TDGF1 TDGF1 ACVRL1 ACVRL1 MSX2 MSX2 ENSFCAP00000037965 ENSFCAP00000037965 ACVR2A ACVR2A BMPR1B BMPR1B SOSTDC1 SOSTDC1 UTF1 UTF1 INHBB INHBB SOX17 SOX17 SMAD9 SMAD9 SMAD7 SMAD7 THY1 THY1 POU3F1 POU3F1 DAZL DAZL INHBA INHBA LOC101092676 LOC101092676 GREM2 GREM2 NOG NOG SNAI3 SNAI3 NOTO NOTO TGFBR1 TGFBR1 MSX1 MSX1 TBX3 TBX3 ERFE ERFE MSANTD3-TMEFF1 MSANTD3-TMEFF1 BMP8B BMP8B FOXD3 FOXD3 SMAD5 SMAD5 BMP4 BMP4 GDF7 GDF7 LOC111559734 LOC111559734 ZIC3 ZIC3 PRR13 PRR13 LOC101100850 LOC101100850 ENSFCAP00000055017 ENSFCAP00000055017 ZFYVE16 ZFYVE16 STRA8 STRA8 ENSFCAP00000056081 ENSFCAP00000056081 BCL6B BCL6B AMH AMH SOHLH2 SOHLH2 ACVR2B ACVR2B CHRDL2 CHRDL2 DPPA5 DPPA5 LOC105261327 LOC105261327 SMAD2 SMAD2 TGFBR2 TGFBR2 ENSFCAP00000061110 ENSFCAP00000061110 DPPA3 DPPA3 ESRRB ESRRB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TBXTT-box transcription factor T. (435 aa)
POU5F1POU domain protein. (360 aa)
NODALNodal growth differentiation factor. (348 aa)
PRDM14PR/SET domain 14. (572 aa)
NANOGNanog homeobox. (311 aa)
TBX10T-box transcription factor 10. (380 aa)
POU1F1POU domain protein. (291 aa)
INHBEInhibin subunit beta E. (349 aa)
EOMESEomesodermin. (713 aa)
NANOS3Nanos C2HC-type zinc finger 3; Belongs to the nanos family. (174 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
AMHR2Anti-Muellerian hormone type-2 receptor; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. (483 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (368 aa)
ZIC1Zic family member 1. (454 aa)
CHRDChordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes. (954 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
SOX15SRY-box 15. (233 aa)
GDF3Growth differentiation factor 3. (365 aa)
SNX16Sorting nexin 16. (344 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
SMAD6Mothers against decapentaplegic homolog. (497 aa)
TFAP2ATranscription factor AP-2 alpha. (437 aa)
FOXA2Forkhead box A2. (457 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
TBX19T-box transcription factor 19. (445 aa)
SMURF1E3 ubiquitin-protein ligase. (757 aa)
PTCHD4Patched domain containing 4. (843 aa)
ZEB2Zinc finger E-box binding homeobox 2. (1217 aa)
SNAI2Uncharacterized protein. (268 aa)
MSTNMyostatin. (375 aa)
GDF11Growth differentiation factor 11. (404 aa)
LOC101084379Homeobox domain-containing protein. (290 aa)
KLF4Kruppel-like factor 4. (485 aa)
ZBTB16Zinc finger and BTB domain containing 16. (679 aa)
NACC1Nucleus accumbens associated 1. (521 aa)
SMURF2E3 ubiquitin-protein ligase. (748 aa)
SKISKI proto-oncogene. (730 aa)
FOXH1Forkhead box H1. (361 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (223 aa)
KLF17Kruppel like factor 17. (394 aa)
BMP15Bone morphogenetic protein 15. (393 aa)
ZBED9Zinc finger BED-type containing 9. (1326 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (510 aa)
NANOS2Nanos C2HC-type zinc finger 2; Belongs to the nanos family. (138 aa)
ETV5ETS variant 5. (608 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
BMP6Bone morphogenetic protein 6. (502 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1424 aa)
BMP10TGF_BETA_2 domain-containing protein. (424 aa)
TWIST1Twist family bHLH transcription factor 1. (200 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1125 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
SOX7Uncharacterized protein. (571 aa)
TWIST2Twist family bHLH transcription factor 2. (160 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
FSTFollistatin. (423 aa)
SMAD3Mothers against decapentaplegic homolog. (457 aa)
GBX2Gastrulation brain homeobox 2. (348 aa)
GDF5Growth differentiation factor 5. (499 aa)
SALL4Spalt like transcription factor 4. (1058 aa)
NBL1NBL1, DAN family BMP antagonist. (176 aa)
SKILSKI like proto-oncogene. (686 aa)
TDGF1Teratocarcinoma-derived growth factor 1. (203 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (517 aa)
MSX2Msh homeobox 2. (267 aa)
ENSFCAP00000037965Homeobox domain-containing protein. (281 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (588 aa)
SOSTDC1Sclerostin domain containing 1. (206 aa)
UTF1Uncharacterized protein. (354 aa)
INHBBInhibin subunit beta B. (407 aa)
SOX17SRY-box transcription factor 17. (406 aa)
SMAD9Mothers against decapentaplegic homolog. (430 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
THY1Thy-1 cell surface antigen. (161 aa)
POU3F1POU domain protein. (452 aa)
DAZLDeleted in azoospermia like. (392 aa)
INHBAInhibin beta A chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins (By similarity). (424 aa)
LOC101092676TGF_BETA_2 domain-containing protein. (410 aa)
GREM2Gremlin 2, DAN family BMP antagonist. (187 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
SNAI3Snail family transcriptional repressor 3. (296 aa)
NOTONotochord homeobox. (241 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
MSX1Msh homeobox 1. (303 aa)
TBX3T-box transcription factor 3. (745 aa)
ERFEErythroferrone. (343 aa)
MSANTD3-TMEFF1MSANTD3-TMEFF1 readthrough. (454 aa)
BMP8BTGF_BETA_2 domain-containing protein. (402 aa)
FOXD3Forkhead box D3. (481 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
GDF7Growth differentiation factor 7. (455 aa)
LOC111559734Bone morphogenetic protein 7. (426 aa)
ZIC3Zic family member 3. (553 aa)
PRR13Proline rich 13. (144 aa)
LOC101100850Uncharacterized protein. (496 aa)
ENSFCAP00000055017Uncharacterized protein. (435 aa)
ZFYVE16Zinc finger FYVE domain-containing protein. (1538 aa)
STRA8Stimulated by retinoic acid 8. (376 aa)
ENSFCAP00000056081Uncharacterized protein. (296 aa)
BCL6BBCL6B transcription repressor. (594 aa)
AMHAnti-Mullerian hormone. (800 aa)
SOHLH2BHLH domain-containing protein. (490 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (523 aa)
CHRDL2Chordin like 2. (440 aa)
DPPA5Developmental pluripotency associated 5. (141 aa)
LOC105261327Left-right determination factor. (367 aa)
SMAD2Mothers against decapentaplegic homolog. (721 aa)
TGFBR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (604 aa)
ENSFCAP00000061110TGF_BETA_2 domain-containing protein. (362 aa)
DPPA3Uncharacterized protein. (151 aa)
ESRRBEstrogen related receptor beta. (454 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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