38 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	TBL1XR1	WD_REPEATS_REGION domain-containing protein. (534 aa)
	CARM1	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (608 aa)
	PPARA	Peroxisome proliferator activated receptor alpha. (468 aa)
	HDAC3	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
	LOC111556172	Uncharacterized protein. (536 aa)
	NRIP1	Nuclear receptor interacting protein 1. (1155 aa)
	NR1H2	Nuclear receptor subfamily 1 group H member 2. (457 aa)
	RARB	Retinoic acid receptor beta. (448 aa)
	CRABP1	Cellular retinoic acid binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (137 aa)
	RXRG	Retinoid X receptor gamma. (463 aa)
	NCOA3	Nuclear receptor coactivator. (1412 aa)
	M3WPU0_FELCA	Uncharacterized protein. (162 aa)
	NCOA2	Nuclear receptor coactivator. (1470 aa)
	ESR1	Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] (595 aa)
	FOXA1	Forkhead box A1. (536 aa)
	ESRRA	Estrogen related receptor alpha. (506 aa)
	NCOR2	Nuclear receptor corepressor 2. (2458 aa)
	GPS2	Uncharacterized protein. (327 aa)
	PPARD	Peroxisome proliferator activated receptor delta. (464 aa)
	ENSFCAP00000030326	Uncharacterized protein. (122 aa)
	NCOR1	Nuclear receptor corepressor 1. (2515 aa)
	TBL1X	Uncharacterized protein. (527 aa)
	NCOA1	Nuclear receptor coactivator. (1492 aa)
	ESR2	Estrogen receptor 2. (574 aa)
	LOC101085801	Uncharacterized protein. (467 aa)
	GATA3	GATA binding protein 3. (444 aa)
	LOC101100603	PUM-HD domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (771 aa)
	ENSFCAP00000045932	Uncharacterized protein. (123 aa)
	RXRA	Retinoid X receptor alpha. (654 aa)
	PGR	Progesterone receptor. (932 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
	RARG	Retinoic acid receptor gamma. (459 aa)
	NR1H3	Nuclear receptor subfamily 1 group H member 3. (498 aa)
	NR1D1	Nuclear receptor subfamily 1 group D member 1. (625 aa)
	TLE3	TLE family member 3, transcriptional corepressor. (778 aa)
	ENSFCAP00000054404	Uncharacterized protein. (284 aa)
	PPARGC1A	PPARG coactivator 1 alpha. (803 aa)
	ESRRG	Estrogen related receptor gamma. (506 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CARM1	ENSFCAP00000030326	ENSFCAP00000004523	ENSFCAP00000030326	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Uncharacterized protein.	0.527
CARM1	ESR1	ENSFCAP00000004523	ENSFCAP00000020448	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]	0.962
CARM1	ESR2	ENSFCAP00000004523	ENSFCAP00000042538	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Estrogen receptor 2.	0.939
CARM1	FOXA1	ENSFCAP00000004523	ENSFCAP00000020793	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Forkhead box A1.	0.445
CARM1	GATA3	ENSFCAP00000004523	ENSFCAP00000044199	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	GATA binding protein 3.	0.441
CARM1	HDAC3	ENSFCAP00000004523	ENSFCAP00000006409	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.412
CARM1	LOC101100603	ENSFCAP00000004523	ENSFCAP00000045269	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	PUM-HD domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.902
CARM1	NCOA1	ENSFCAP00000004523	ENSFCAP00000042028	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Nuclear receptor coactivator.	0.646
CARM1	NCOA2	ENSFCAP00000004523	ENSFCAP00000018792	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Nuclear receptor coactivator.	0.673
CARM1	NCOA3	ENSFCAP00000004523	ENSFCAP00000013944	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Nuclear receptor coactivator.	0.977
CARM1	NCOR1	ENSFCAP00000004523	ENSFCAP00000033436	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Nuclear receptor corepressor 1.	0.461
CARM1	NCOR2	ENSFCAP00000004523	ENSFCAP00000024270	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Nuclear receptor corepressor 2.	0.501
CARM1	TBL1X	ENSFCAP00000004523	ENSFCAP00000041043	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Uncharacterized protein.	0.401
CARM1	TBL1XR1	ENSFCAP00000004523	ENSFCAP00000002262	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	WD_REPEATS_REGION domain-containing protein.	0.401
CRABP1	LOC101085801	ENSFCAP00000009766	ENSFCAP00000043848	Cellular retinoic acid binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	Uncharacterized protein.	0.735
CRABP1	NCOA2	ENSFCAP00000009766	ENSFCAP00000018792	Cellular retinoic acid binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	Nuclear receptor coactivator.	0.618
CRABP1	RARB	ENSFCAP00000009766	ENSFCAP00000009659	Cellular retinoic acid binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	Retinoic acid receptor beta.	0.732
CRABP1	RARG	ENSFCAP00000009766	ENSFCAP00000051056	Cellular retinoic acid binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	Retinoic acid receptor gamma.	0.514
CRABP1	RXRA	ENSFCAP00000009766	ENSFCAP00000049471	Cellular retinoic acid binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	Retinoid X receptor alpha.	0.480
CRABP1	RXRG	ENSFCAP00000009766	ENSFCAP00000009995	Cellular retinoic acid binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	Retinoid X receptor gamma.	0.780