STRINGSTRING
PPARA PPARA RARB RARB CRABP1 CRABP1 RXRG RXRG PPARD PPARD LOC101085801 LOC101085801 ENSFCAP00000045932 ENSFCAP00000045932 RXRA RXRA PPARG PPARG RARG RARG PPARGC1A PPARGC1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
RARBRetinoic acid receptor beta. (448 aa)
CRABP1Cellular retinoic acid binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (137 aa)
RXRGRetinoid X receptor gamma. (463 aa)
PPARDPeroxisome proliferator activated receptor delta. (464 aa)
LOC101085801Uncharacterized protein. (467 aa)
ENSFCAP00000045932Uncharacterized protein. (123 aa)
RXRARetinoid X receptor alpha. (654 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
RARGRetinoic acid receptor gamma. (459 aa)
PPARGC1APPARG coactivator 1 alpha. (803 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.