5 items (Felis catus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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proteins of unknown 3D structure

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textmining

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protein homology

Your Input:
	NCOA3	Nuclear receptor coactivator. (1412 aa)
	NCOA2	Nuclear receptor coactivator. (1470 aa)
	ESR1	Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] (595 aa)
	NCOA1	Nuclear receptor coactivator. (1492 aa)
	ESR2	Estrogen receptor 2. (574 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ESR1	ESR2	ENSFCAP00000020448	ENSFCAP00000042538	Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]	Estrogen receptor 2.	0.997
ESR1	NCOA1	ENSFCAP00000020448	ENSFCAP00000042028	Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]	Nuclear receptor coactivator.	0.998
ESR1	NCOA2	ENSFCAP00000020448	ENSFCAP00000018792	Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]	Nuclear receptor coactivator.	0.996
ESR1	NCOA3	ENSFCAP00000020448	ENSFCAP00000013944	Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]	Nuclear receptor coactivator.	0.998
ESR2	ESR1	ENSFCAP00000042538	ENSFCAP00000020448	Estrogen receptor 2.	Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]	0.997
ESR2	NCOA1	ENSFCAP00000042538	ENSFCAP00000042028	Estrogen receptor 2.	Nuclear receptor coactivator.	0.989
ESR2	NCOA2	ENSFCAP00000042538	ENSFCAP00000018792	Estrogen receptor 2.	Nuclear receptor coactivator.	0.957
ESR2	NCOA3	ENSFCAP00000042538	ENSFCAP00000013944	Estrogen receptor 2.	Nuclear receptor coactivator.	0.978
NCOA1	ESR1	ENSFCAP00000042028	ENSFCAP00000020448	Nuclear receptor coactivator.	Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]	0.998
NCOA1	ESR2	ENSFCAP00000042028	ENSFCAP00000042538	Nuclear receptor coactivator.	Estrogen receptor 2.	0.989
NCOA1	NCOA2	ENSFCAP00000042028	ENSFCAP00000018792	Nuclear receptor coactivator.	Nuclear receptor coactivator.	0.996
NCOA1	NCOA3	ENSFCAP00000042028	ENSFCAP00000013944	Nuclear receptor coactivator.	Nuclear receptor coactivator.	0.979
NCOA2	ESR1	ENSFCAP00000018792	ENSFCAP00000020448	Nuclear receptor coactivator.	Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]	0.996
NCOA2	ESR2	ENSFCAP00000018792	ENSFCAP00000042538	Nuclear receptor coactivator.	Estrogen receptor 2.	0.957
NCOA2	NCOA1	ENSFCAP00000018792	ENSFCAP00000042028	Nuclear receptor coactivator.	Nuclear receptor coactivator.	0.996
NCOA2	NCOA3	ENSFCAP00000018792	ENSFCAP00000013944	Nuclear receptor coactivator.	Nuclear receptor coactivator.	0.968
NCOA3	ESR1	ENSFCAP00000013944	ENSFCAP00000020448	Nuclear receptor coactivator.	Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]	0.998
NCOA3	ESR2	ENSFCAP00000013944	ENSFCAP00000042538	Nuclear receptor coactivator.	Estrogen receptor 2.	0.978
NCOA3	NCOA1	ENSFCAP00000013944	ENSFCAP00000042028	Nuclear receptor coactivator.	Nuclear receptor coactivator.	0.979
NCOA3	NCOA2	ENSFCAP00000013944	ENSFCAP00000018792	Nuclear receptor coactivator.	Nuclear receptor coactivator.	0.968