STRINGSTRING
GCDH GCDH MCCC1 MCCC1 ALDH18A1 ALDH18A1 UPB1 UPB1 ALDH8A1 ALDH8A1 ECHDC2 ECHDC2 ACLY ACLY METAP1D METAP1D MECR MECR ACOX2 ACOX2 ACSS2 ACSS2 GAD2 GAD2 CARTPT CARTPT CARNS1 CARNS1 ACADSB ACADSB ALDH9A1 ALDH9A1 ACSM5 ACSM5 ADH5 ADH5 ACSL1 ACSL1 ALDH3A1 ALDH3A1 OXCT1 OXCT1 CHDH CHDH ACSBG1 ACSBG1 CPT1C CPT1C ALDH6A1 ALDH6A1 AASDH AASDH HMGCLL1 HMGCLL1 HSD17B8 HSD17B8 EHHADH EHHADH CRYL1 CRYL1 ECI1 ECI1 ECHDC1 ECHDC1 GLUD1 GLUD1 CNDP2 CNDP2 ACACB ACACB HSD17B4 HSD17B4 ALDH16A1 ALDH16A1 HAO1 HAO1 FASN FASN ACSL3 ACSL3 GLS2 GLS2 MCAT MCAT DHTKD1 DHTKD1 ACSS3 ACSS3 MAOB MAOB LOC101093157 LOC101093157 VAT1 VAT1 MCCC2 MCCC2 HSDL2 HSDL2 ACSS1 ACSS1 AACS AACS ILVBL ILVBL HADHA HADHA HADHB HADHB ECHS1 ECHS1 ACOX3 ACOX3 PHYKPL PHYKPL ACSM4 ACSM4 BDH1 BDH1 AMACR AMACR CDO1 CDO1 ADO ADO ACOX1 ACOX1 AASDHPPT AASDHPPT ALDH3B1 ALDH3B1 ACAD11 ACAD11 ACYP1 ACYP1 CARNMT1 CARNMT1 MRTFB MRTFB LOC101100805 LOC101100805 ACADS ACADS CBR4 CBR4 ACADL ACADL ADHFE1 ADHFE1 ETFDH ETFDH HPDL HPDL GLO1 GLO1 PPT1 PPT1 LOC101100387 LOC101100387 ALDH5A1 ALDH5A1 LOC101089901 LOC101089901 ALDH2 ALDH2 HIBADH HIBADH ESD ESD GADL1 GADL1 EPHX3 EPHX3 LOC101083645 LOC101083645 HOGA1 HOGA1 SCD SCD ACADM ACADM CRYZ CRYZ M3XGE2_FELCA M3XGE2_FELCA AOC2 AOC2 CB3H15orf41 CB3H15orf41 CNDP1 CNDP1 PCCA PCCA CPT1B CPT1B ENSFCAP00000030154 ENSFCAP00000030154 RIDA RIDA ECI2 ECI2 ACSL4 ACSL4 UBIAD1 UBIAD1 GLS GLS ACACA ACACA PCCB PCCB AGXT AGXT BBOX1 BBOX1 CROT CROT ALDH1B1 ALDH1B1 MLYCD MLYCD CPT2 CPT2 ACSL6 ACSL6 HMGCS2 HMGCS2 ENSFCAP00000041919 ENSFCAP00000041919 ACYP2 ACYP2 ABAT ABAT ENSFCAP00000044681 ENSFCAP00000044681 IYD IYD SMOX SMOX LOC105259663 LOC105259663 MAOA MAOA HTD2 HTD2 ACADVL ACADVL ACAA2 ACAA2 GLUL GLUL OXSM OXSM HYKK HYKK ACOXL ACOXL ETFB ETFB L2HGDH L2HGDH ACOT13 ACOT13 LOC101080592 LOC101080592 PECR PECR ALDH7A1 ALDH7A1 ACSL5 ACSL5 SLC27A1 SLC27A1 AGXT2 AGXT2 CSAD CSAD UBE2E3 UBE2E3 ACAA1 ACAA1 HIBCH HIBCH AKR1A1 AKR1A1 BDH2 BDH2 CPT1A CPT1A ALDH3A2 ALDH3A2 ADH4 ADH4 LOC102900010 LOC102900010 ENSFCAP00000054718 ENSFCAP00000054718 ENSFCAP00000055181 ENSFCAP00000055181 ETFA ETFA IVD IVD LOC101088562 LOC101088562 ACSM3 ACSM3 LOC102901059 LOC102901059 GAD1 GAD1 TOMT TOMT ENSFCAP00000058183 ENSFCAP00000058183 PPT2 PPT2 HAO2 HAO2 ENSFCAP00000058936 ENSFCAP00000058936 ACAT2 ACAT2 AUH AUH ACAT1 ACAT1 CRAT CRAT HAGH HAGH ACAD8 ACAD8 ENSFCAP00000061584 ENSFCAP00000061584 HADH HADH ACOT12 ACOT12 ACSF3 ACSF3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GCDHGlutaryl-CoA dehydrogenase. (438 aa)
MCCC1Methylcrotonoyl-CoA carboxylase 1. (725 aa)
ALDH18A1Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (797 aa)
UPB1Beta-ureidopropionase 1. (384 aa)
ALDH8A1Aldehyde dehydrogenase 8 family member A1; Belongs to the aldehyde dehydrogenase family. (518 aa)
ECHDC2Enoyl-CoA hydratase domain containing 2; Belongs to the enoyl-CoA hydratase/isomerase family. (296 aa)
ACLYATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. (1115 aa)
METAP1DMethionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). (439 aa)
MECRMitochondrial trans-2-enoyl-CoA reductase. (374 aa)
ACOX2Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (681 aa)
ACSS2Acyl-CoA synthetase short chain family member 2. (784 aa)
GAD2Glutamate decarboxylase 2. (585 aa)
CARTPTCART prepropeptide. (116 aa)
CARNS1Carnosine synthase 1. (967 aa)
ACADSBAcyl-CoA dehydrogenase short/branched chain. (432 aa)
ALDH9A1Aldehyde dehydrogenase 9 family member A1; Belongs to the aldehyde dehydrogenase family. (518 aa)
ACSM5Acyl-CoA synthetase medium chain family member 5. (588 aa)
ADH5S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (374 aa)
ACSL1Acyl-CoA synthetase long chain family member 1. (698 aa)
ALDH3A1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (478 aa)
OXCT1Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (519 aa)
CHDHCholine dehydrogenase. (594 aa)
ACSBG1Acyl-CoA synthetase bubblegum family member 1. (815 aa)
CPT1CCarnitine palmitoyltransferase 1C; Belongs to the carnitine/choline acetyltransferase family. (803 aa)
ALDH6A1Aldehyde dehydrogenase 6 family member A1. (534 aa)
AASDHAminoadipate-semialdehyde dehydrogenase. (1096 aa)
HMGCLL13-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. (340 aa)
HSD17B8Hydroxysteroid 17-beta dehydrogenase 8; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (285 aa)
EHHADHEnoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (806 aa)
CRYL1Crystallin lambda 1. (318 aa)
ECI1Enoyl-CoA delta isomerase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (302 aa)
ECHDC1Ethylmalonyl-CoA decarboxylase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (278 aa)
GLUD1ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (558 aa)
CNDP2Carnosine dipeptidase 2. (475 aa)
ACACBAcetyl-CoA carboxylase beta. (2447 aa)
HSD17B4Hydroxysteroid 17-beta dehydrogenase 4. (736 aa)
ALDH16A1Aldehyde dehydrogenase family 16 member A1. (802 aa)
HAO1Hydroxyacid oxidase 1. (370 aa)
FASNFatty acid synthase. (2655 aa)
ACSL3Acyl-CoA synthetase long chain family member 3. (720 aa)
GLS2Glutaminase 2. (602 aa)
MCATMalonyl-CoA-acyl carrier protein transacylase. (383 aa)
DHTKD1Dehydrogenase E1 and transketolase domain containing 1. (920 aa)
ACSS3Acyl-CoA synthetase short chain family member 3. (854 aa)
MAOBAmine oxidase. (520 aa)
LOC101093157Amine oxidase. (618 aa)
VAT1Vesicle amine transport 1. (391 aa)
MCCC2Uncharacterized protein. (563 aa)
HSDL2Hydroxysteroid dehydrogenase like 2. (418 aa)
ACSS1Acetyl-coenzyme A synthetase. (752 aa)
AACSAcetoacetyl-CoA synthetase. (672 aa)
ILVBLIlvB acetolactate synthase like; Belongs to the TPP enzyme family. (648 aa)
HADHAHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa)
HADHBHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family. (475 aa)
ECHS1Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family. (324 aa)
ACOX3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (700 aa)
PHYKPL5-phosphohydroxy-L-lysine phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (450 aa)
ACSM4Acyl-CoA synthetase medium chain family member 4. (579 aa)
BDH13-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (382 aa)
AMACRAlpha-methylacyl-CoA racemase. (382 aa)
CDO1Cysteine dioxygenase. (200 aa)
ADO2-aminoethanethiol dioxygenase. (270 aa)
ACOX1Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (661 aa)
AASDHPPTAminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase. (309 aa)
ALDH3B1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (489 aa)
ACAD11Acyl-CoA dehydrogenase family member 11. (781 aa)
ACYP1Acylphosphatase. (131 aa)
CARNMT1Carnosine N-methyltransferase 1. (411 aa)
MRTFBMyocardin related transcription factor B. (1118 aa)
LOC101100805PKS_ER domain-containing protein. (381 aa)
ACADSAcyl-CoA dehydrogenase short chain. (412 aa)
CBR4Carbonyl reductase 4. (237 aa)
ACADLAcyl-CoA dehydrogenase long chain. (430 aa)
ADHFE1Fe-ADH domain-containing protein. (500 aa)
ETFDHElectron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (617 aa)
HPDL4-hydroxyphenylpyruvate dioxygenase. (372 aa)
GLO1Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (184 aa)
PPT1Palmitoyl-protein thioesterase 1. (289 aa)
LOC101100387PKS_ER domain-containing protein. (375 aa)
ALDH5A1Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (523 aa)
LOC101089901Uncharacterized protein. (485 aa)
ALDH2Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (517 aa)
HIBADH3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (336 aa)
ESDS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (282 aa)
GADL1Glutamate decarboxylase like 1. (521 aa)
EPHX3Epoxide hydrolase 3. (360 aa)
LOC101083645PKS_ER domain-containing protein. (453 aa)
HOGA14-hydroxy-2-oxoglutarate aldolase 1; Belongs to the DapA family. (327 aa)
SCDStearoyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (405 aa)
ACADMAcyl-CoA dehydrogenase medium chain. (445 aa)
CRYZCrystallin zeta. (330 aa)
M3XGE2_FELCAUncharacterized protein. (87 aa)
AOC2Amine oxidase. (756 aa)
CB3H15orf41Chromosome B3 C15orf41 homolog. (305 aa)
CNDP1Carnosine dipeptidase 1. (515 aa)
PCCAPropionyl-CoA carboxylase subunit alpha. (759 aa)
CPT1BCarnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family. (772 aa)
ENSFCAP000000301544HBT domain-containing protein. (200 aa)
RIDAReactive intermediate imine deaminase A homolog. (137 aa)
ECI2Enoyl-CoA delta isomerase 2. (415 aa)
ACSL4Acyl-CoA synthetase long chain family member 4. (711 aa)
UBIAD1UbiA prenyltransferase domain containing 1. (324 aa)
GLSGlutaminase. (672 aa)
ACACAAcetyl-CoA carboxylase alpha. (2385 aa)
PCCBPropionyl-CoA carboxylase subunit beta. (570 aa)
AGXTSerine--pyruvate aminotransferase, mitochondrial; Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). (414 aa)
BBOX1Gamma-butyrobetaine hydroxylase 1. (387 aa)
CROTCarnitine O-octanoyltransferase; Belongs to the carnitine/choline acetyltransferase family. (612 aa)
ALDH1B1Aldehyde dehydrogenase 1 family member B1; Belongs to the aldehyde dehydrogenase family. (519 aa)
MLYCDMalonyl-CoA decarboxylase. (496 aa)
CPT2Carnitine palmitoyltransferase 2; Belongs to the carnitine/choline acetyltransferase family. (696 aa)
ACSL6AMP-binding domain-containing protein. (722 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
ENSFCAP00000041919CoA carboxyltransferase N-terminal domain-containing protein. (336 aa)
ACYP2Acylphosphatase. (99 aa)
ABAT4-aminobutyrate aminotransferase. (570 aa)
ENSFCAP00000044681Aldedh domain-containing protein. (163 aa)
IYDIodotyrosine deiodinase. (289 aa)
SMOXSpermine oxidase. (585 aa)
LOC105259663Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (439 aa)
MAOAAmine oxidase. (1178 aa)
HTD2Hydroxyacyl-thioester dehydratase type 2. (167 aa)
ACADVLAcyl-CoA dehydrogenase very long chain. (655 aa)
ACAA2Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
GLULGlutamine synthetase. (506 aa)
OXSM3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (460 aa)
HYKKHydroxylysine kinase. (376 aa)
ACOXLAcyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (580 aa)
ETFBElectron transfer flavoprotein subunit beta. (255 aa)
L2HGDHL-2-hydroxyglutarate dehydrogenase. (463 aa)
ACOT13Acyl-CoA thioesterase 13. (140 aa)
LOC101080592Amine oxidase. (763 aa)
PECRPeroxisomal trans-2-enoyl-CoA reductase. (366 aa)
ALDH7A1Aldehyde dehydrogenase 7 family member A1; Belongs to the aldehyde dehydrogenase family. (638 aa)
ACSL5Acyl-CoA synthetase long chain family member 5. (670 aa)
SLC27A1Solute carrier family 27 member 1. (796 aa)
AGXT2Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (496 aa)
CSADCysteine sulfinic acid decarboxylase. (540 aa)
UBE2E3Ubiquitin conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family. (241 aa)
ACAA1Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (456 aa)
HIBCH3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (390 aa)
AKR1A1Aldo-keto reductase family 1 member A1. (356 aa)
BDH23-hydroxybutyrate dehydrogenase 2. (250 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (773 aa)
ALDH3A2Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (515 aa)
ADH4Alcohol dehydrogenase 4 (class II), pi polypeptide. (447 aa)
LOC102900010AMP-binding domain-containing protein. (758 aa)
ENSFCAP00000054718Tnp_22_dsRBD domain-containing protein. (268 aa)
ENSFCAP00000055181Tnp_22_dsRBD domain-containing protein. (339 aa)
ETFAElectron transfer flavoprotein subunit alpha. (418 aa)
IVDIsovaleryl-CoA dehydrogenase. (700 aa)
LOC101088562Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (448 aa)
ACSM3Acyl-CoA synthetase medium chain family member 3. (640 aa)
LOC102901059Uncharacterized protein. (127 aa)
GAD1Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family. (611 aa)
TOMTUncharacterized protein. (318 aa)
ENSFCAP00000058183Uncharacterized protein. (176 aa)
PPT2Palmitoyl-protein thioesterase 2. (309 aa)
HAO2Hydroxyacid oxidase 2. (377 aa)
ENSFCAP00000058936Uncharacterized protein. (171 aa)
ACAT2Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa)
AUHAU RNA binding methylglutaconyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (494 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (517 aa)
CRATCarnitine O-acetyltransferase; Belongs to the carnitine/choline acetyltransferase family. (626 aa)
HAGHHydroxyacylglutathione hydrolase. (342 aa)
ACAD8Acyl-CoA dehydrogenase family member 8. (487 aa)
ENSFCAP00000061584Uncharacterized protein. (359 aa)
HADHHydroxyacyl-CoA dehydrogenase. (338 aa)
ACOT12Acyl-CoA thioesterase 12. (569 aa)
ACSF3Acyl-CoA synthetase family member 3. (586 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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