STRINGSTRING
MCCC1 MCCC1 ECHDC2 ECHDC2 ACLY ACLY MECR MECR ACOX2 ACOX2 ACSS2 ACSS2 CARTPT CARTPT ACADSB ACADSB OXCT1 OXCT1 ALDH6A1 ALDH6A1 AASDH AASDH HMGCLL1 HMGCLL1 HSD17B8 HSD17B8 EHHADH EHHADH ECI1 ECI1 ECHDC1 ECHDC1 HSD17B4 HSD17B4 FASN FASN MCAT MCAT ACSS3 ACSS3 MCCC2 MCCC2 HSDL2 HSDL2 AACS AACS HADHA HADHA HADHB HADHB ECHS1 ECHS1 ACOX3 ACOX3 ACSM4 ACSM4 BDH1 BDH1 AMACR AMACR ACOX1 ACOX1 AASDHPPT AASDHPPT ACAD11 ACAD11 ACADS ACADS CBR4 CBR4 ACADL ACADL ETFDH ETFDH HPDL HPDL HIBADH HIBADH SCD SCD ACADM ACADM PCCA PCCA ECI2 ECI2 ACACA ACACA PCCB PCCB ALDH1B1 ALDH1B1 MLYCD MLYCD CPT2 CPT2 HMGCS2 HMGCS2 ENSFCAP00000041919 ENSFCAP00000041919 HTD2 HTD2 ACADVL ACADVL ACAA2 ACAA2 OXSM OXSM ACOXL ACOXL ETFB ETFB ACAA1 ACAA1 HIBCH HIBCH BDH2 BDH2 ENSFCAP00000055181 ENSFCAP00000055181 ETFA ETFA IVD IVD LOC101088562 LOC101088562 LOC102901059 LOC102901059 ACAT2 ACAT2 AUH AUH ACAT1 ACAT1 CRAT CRAT ACAD8 ACAD8 ENSFCAP00000061584 ENSFCAP00000061584 HADH HADH ACSF3 ACSF3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MCCC1Methylcrotonoyl-CoA carboxylase 1. (725 aa)
ECHDC2Enoyl-CoA hydratase domain containing 2; Belongs to the enoyl-CoA hydratase/isomerase family. (296 aa)
ACLYATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. (1115 aa)
MECRMitochondrial trans-2-enoyl-CoA reductase. (374 aa)
ACOX2Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (681 aa)
ACSS2Acyl-CoA synthetase short chain family member 2. (784 aa)
CARTPTCART prepropeptide. (116 aa)
ACADSBAcyl-CoA dehydrogenase short/branched chain. (432 aa)
OXCT1Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (519 aa)
ALDH6A1Aldehyde dehydrogenase 6 family member A1. (534 aa)
AASDHAminoadipate-semialdehyde dehydrogenase. (1096 aa)
HMGCLL13-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. (340 aa)
HSD17B8Hydroxysteroid 17-beta dehydrogenase 8; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (285 aa)
EHHADHEnoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (806 aa)
ECI1Enoyl-CoA delta isomerase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (302 aa)
ECHDC1Ethylmalonyl-CoA decarboxylase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (278 aa)
HSD17B4Hydroxysteroid 17-beta dehydrogenase 4. (736 aa)
FASNFatty acid synthase. (2655 aa)
MCATMalonyl-CoA-acyl carrier protein transacylase. (383 aa)
ACSS3Acyl-CoA synthetase short chain family member 3. (854 aa)
MCCC2Uncharacterized protein. (563 aa)
HSDL2Hydroxysteroid dehydrogenase like 2. (418 aa)
AACSAcetoacetyl-CoA synthetase. (672 aa)
HADHAHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa)
HADHBHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family. (475 aa)
ECHS1Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family. (324 aa)
ACOX3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (700 aa)
ACSM4Acyl-CoA synthetase medium chain family member 4. (579 aa)
BDH13-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (382 aa)
AMACRAlpha-methylacyl-CoA racemase. (382 aa)
ACOX1Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (661 aa)
AASDHPPTAminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase. (309 aa)
ACAD11Acyl-CoA dehydrogenase family member 11. (781 aa)
ACADSAcyl-CoA dehydrogenase short chain. (412 aa)
CBR4Carbonyl reductase 4. (237 aa)
ACADLAcyl-CoA dehydrogenase long chain. (430 aa)
ETFDHElectron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (617 aa)
HPDL4-hydroxyphenylpyruvate dioxygenase. (372 aa)
HIBADH3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (336 aa)
SCDStearoyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (405 aa)
ACADMAcyl-CoA dehydrogenase medium chain. (445 aa)
PCCAPropionyl-CoA carboxylase subunit alpha. (759 aa)
ECI2Enoyl-CoA delta isomerase 2. (415 aa)
ACACAAcetyl-CoA carboxylase alpha. (2385 aa)
PCCBPropionyl-CoA carboxylase subunit beta. (570 aa)
ALDH1B1Aldehyde dehydrogenase 1 family member B1; Belongs to the aldehyde dehydrogenase family. (519 aa)
MLYCDMalonyl-CoA decarboxylase. (496 aa)
CPT2Carnitine palmitoyltransferase 2; Belongs to the carnitine/choline acetyltransferase family. (696 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
ENSFCAP00000041919CoA carboxyltransferase N-terminal domain-containing protein. (336 aa)
HTD2Hydroxyacyl-thioester dehydratase type 2. (167 aa)
ACADVLAcyl-CoA dehydrogenase very long chain. (655 aa)
ACAA2Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
OXSM3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (460 aa)
ACOXLAcyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (580 aa)
ETFBElectron transfer flavoprotein subunit beta. (255 aa)
ACAA1Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (456 aa)
HIBCH3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (390 aa)
BDH23-hydroxybutyrate dehydrogenase 2. (250 aa)
ENSFCAP00000055181Tnp_22_dsRBD domain-containing protein. (339 aa)
ETFAElectron transfer flavoprotein subunit alpha. (418 aa)
IVDIsovaleryl-CoA dehydrogenase. (700 aa)
LOC101088562Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (448 aa)
LOC102901059Uncharacterized protein. (127 aa)
ACAT2Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa)
AUHAU RNA binding methylglutaconyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (494 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (517 aa)
CRATCarnitine O-acetyltransferase; Belongs to the carnitine/choline acetyltransferase family. (626 aa)
ACAD8Acyl-CoA dehydrogenase family member 8. (487 aa)
ENSFCAP00000061584Uncharacterized protein. (359 aa)
HADHHydroxyacyl-CoA dehydrogenase. (338 aa)
ACSF3Acyl-CoA synthetase family member 3. (586 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (10%) [HD]