(47 nodes) Mixed, incl. beta-Alanine metabolism, and Glutamate and glutamine metabolism network (Felis catus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ALDH18A1	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (797 aa)
	UPB1	Beta-ureidopropionase 1. (384 aa)
	GAD2	Glutamate decarboxylase 2. (585 aa)
	CARNS1	Carnosine synthase 1. (967 aa)
	ALDH9A1	Aldehyde dehydrogenase 9 family member A1; Belongs to the aldehyde dehydrogenase family. (518 aa)
	ADH5	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (374 aa)
	ALDH3A1	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (478 aa)
	CHDH	Choline dehydrogenase. (594 aa)
	CRYL1	Crystallin lambda 1. (318 aa)
	GLUD1	ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (558 aa)
	CNDP2	Carnosine dipeptidase 2. (475 aa)
	ALDH16A1	Aldehyde dehydrogenase family 16 member A1. (802 aa)
	GLS2	Glutaminase 2. (602 aa)
	MAOB	Amine oxidase. (520 aa)
	LOC101093157	Amine oxidase. (618 aa)
	ACSS1	Acetyl-coenzyme A synthetase. (752 aa)
	PHYKPL	5-phosphohydroxy-L-lysine phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (450 aa)
	CDO1	Cysteine dioxygenase. (200 aa)
	ADO	2-aminoethanethiol dioxygenase. (270 aa)
	ALDH3B1	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (489 aa)
	ACYP1	Acylphosphatase. (131 aa)
	CARNMT1	Carnosine N-methyltransferase 1. (411 aa)
	LOC101100387	PKS_ER domain-containing protein. (375 aa)
	ALDH5A1	Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (523 aa)
	LOC101089901	Uncharacterized protein. (485 aa)
	ALDH2	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (517 aa)
	ESD	S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (282 aa)
	GADL1	Glutamate decarboxylase like 1. (521 aa)
	AOC2	Amine oxidase. (756 aa)
	CNDP1	Carnosine dipeptidase 1. (515 aa)
	GLS	Glutaminase. (672 aa)
	BBOX1	Gamma-butyrobetaine hydroxylase 1. (387 aa)
	ACYP2	Acylphosphatase. (99 aa)
	ABAT	4-aminobutyrate aminotransferase. (570 aa)
	SMOX	Spermine oxidase. (585 aa)
	MAOA	Amine oxidase. (1178 aa)
	GLUL	Glutamine synthetase. (506 aa)
	HYKK	Hydroxylysine kinase. (376 aa)
	L2HGDH	L-2-hydroxyglutarate dehydrogenase. (463 aa)
	ALDH7A1	Aldehyde dehydrogenase 7 family member A1; Belongs to the aldehyde dehydrogenase family. (638 aa)
	AGXT2	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (496 aa)
	CSAD	Cysteine sulfinic acid decarboxylase. (540 aa)
	AKR1A1	Aldo-keto reductase family 1 member A1. (356 aa)
	ALDH3A2	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (515 aa)
	GAD1	Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family. (611 aa)
	TOMT	Uncharacterized protein. (318 aa)
	ACOT12	Acyl-CoA thioesterase 12. (569 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABAT	ACSS1	ENSFCAP00000042464	ENSFCAP00000013493	4-aminobutyrate aminotransferase.	Acetyl-coenzyme A synthetase.	0.828
ABAT	ALDH16A1	ENSFCAP00000042464	ENSFCAP00000008518	4-aminobutyrate aminotransferase.	Aldehyde dehydrogenase family 16 member A1.	0.946
ABAT	ALDH18A1	ENSFCAP00000042464	ENSFCAP00000001320	4-aminobutyrate aminotransferase.	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	0.437
ABAT	ALDH2	ENSFCAP00000042464	ENSFCAP00000022517	4-aminobutyrate aminotransferase.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.946
ABAT	ALDH3A1	ENSFCAP00000042464	ENSFCAP00000004809	4-aminobutyrate aminotransferase.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.946
ABAT	ALDH3A2	ENSFCAP00000042464	ENSFCAP00000054227	4-aminobutyrate aminotransferase.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.946
ABAT	ALDH3B1	ENSFCAP00000042464	ENSFCAP00000018094	4-aminobutyrate aminotransferase.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.946
ABAT	ALDH5A1	ENSFCAP00000042464	ENSFCAP00000022251	4-aminobutyrate aminotransferase.	Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.988
ABAT	ALDH7A1	ENSFCAP00000042464	ENSFCAP00000052117	4-aminobutyrate aminotransferase.	Aldehyde dehydrogenase 7 family member A1; Belongs to the aldehyde dehydrogenase family.	0.943
ABAT	ALDH9A1	ENSFCAP00000042464	ENSFCAP00000003978	4-aminobutyrate aminotransferase.	Aldehyde dehydrogenase 9 family member A1; Belongs to the aldehyde dehydrogenase family.	0.946
ABAT	CARNS1	ENSFCAP00000042464	ENSFCAP00000003132	4-aminobutyrate aminotransferase.	Carnosine synthase 1.	0.902
ABAT	CNDP1	ENSFCAP00000042464	ENSFCAP00000027203	4-aminobutyrate aminotransferase.	Carnosine dipeptidase 1.	0.941
ABAT	CNDP2	ENSFCAP00000042464	ENSFCAP00000007670	4-aminobutyrate aminotransferase.	Carnosine dipeptidase 2.	0.941
ABAT	CSAD	ENSFCAP00000042464	ENSFCAP00000053388	4-aminobutyrate aminotransferase.	Cysteine sulfinic acid decarboxylase.	0.447
ABAT	GAD1	ENSFCAP00000042464	ENSFCAP00000057074	4-aminobutyrate aminotransferase.	Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family.	0.967
ABAT	GAD2	ENSFCAP00000042464	ENSFCAP00000002157	4-aminobutyrate aminotransferase.	Glutamate decarboxylase 2.	0.974
ABAT	GADL1	ENSFCAP00000042464	ENSFCAP00000023862	4-aminobutyrate aminotransferase.	Glutamate decarboxylase like 1.	0.942
ABAT	GLUD1	ENSFCAP00000042464	ENSFCAP00000007384	4-aminobutyrate aminotransferase.	ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.833
ABAT	L2HGDH	ENSFCAP00000042464	ENSFCAP00000050254	4-aminobutyrate aminotransferase.	L-2-hydroxyglutarate dehydrogenase.	0.415
ABAT	LOC101089901	ENSFCAP00000042464	ENSFCAP00000022492	4-aminobutyrate aminotransferase.	Uncharacterized protein.	0.488