(26 nodes) Pyrimidine metabolism, and Pyridine nucleotide biosynthesis network (Felis catus)

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	NAPRT	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (538 aa)
	NT5C1A	5'-nucleotidase, cytosolic IA. (348 aa)
	PNP	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa)
	UPP1	Uridine phosphorylase 1. (354 aa)
	UCK1	PRK domain-containing protein. (401 aa)
	NUDT12	Nudix hydrolase 12. (477 aa)
	UPRT	Uracil phosphoribosyltransferase homolog. (306 aa)
	DCK	Deoxycytidine kinase. (269 aa)
	NT5C3B	5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (300 aa)
	CMPK2	Cytidine/uridine monophosphate kinase 2. (442 aa)
	QPRT	Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (299 aa)
	NT5C2	5'-nucleotidase, cytosolic II. (561 aa)
	DCTPP1	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism. (170 aa)
	ADA2	Adenosine deaminase 2. (563 aa)
	NT5C	5', 3'-nucleotidase, cytosolic. (205 aa)
	CDA	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (146 aa)
	APRT	Adenine phosphoribosyltransferase. (180 aa)
	DCTD	CMP/dCMP-type deaminase domain-containing protein. (493 aa)
	UCK2	Uridine-cytidine kinase; Belongs to the uridine kinase family. (261 aa)
	NT5M	5',3'-nucleotidase, mitochondrial. (235 aa)
	UCKL1	Uridine-cytidine kinase; Belongs to the uridine kinase family. (995 aa)
	CMPK1	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (318 aa)
	DGUOK	Deoxyguanosine kinase. (319 aa)
	NMNAT3	Nicotinamide-nucleotide adenylyltransferase. (323 aa)
	NT5E	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (587 aa)
	RDH14	Uncharacterized protein. (770 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADA2	APRT	ENSFCAP00000028652	ENSFCAP00000033614	Adenosine deaminase 2.	Adenine phosphoribosyltransferase.	0.760
ADA2	DCK	ENSFCAP00000028652	ENSFCAP00000020325	Adenosine deaminase 2.	Deoxycytidine kinase.	0.900
ADA2	NT5C	ENSFCAP00000028652	ENSFCAP00000032366	Adenosine deaminase 2.	5', 3'-nucleotidase, cytosolic.	0.934
ADA2	NT5C1A	ENSFCAP00000028652	ENSFCAP00000005600	Adenosine deaminase 2.	5'-nucleotidase, cytosolic IA.	0.900
ADA2	NT5C2	ENSFCAP00000028652	ENSFCAP00000026132	Adenosine deaminase 2.	5'-nucleotidase, cytosolic II.	0.914
ADA2	NT5C3B	ENSFCAP00000028652	ENSFCAP00000023807	Adenosine deaminase 2.	5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family.	0.912
ADA2	NT5E	ENSFCAP00000028652	ENSFCAP00000060576	Adenosine deaminase 2.	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.	0.961
ADA2	NT5M	ENSFCAP00000028652	ENSFCAP00000049088	Adenosine deaminase 2.	5',3'-nucleotidase, mitochondrial.	0.934
ADA2	PNP	ENSFCAP00000028652	ENSFCAP00000006438	Adenosine deaminase 2.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.964
ADA2	RDH14	ENSFCAP00000028652	ENSFCAP00000061327	Adenosine deaminase 2.	Uncharacterized protein.	0.900
ADA2	UPP1	ENSFCAP00000028652	ENSFCAP00000011034	Adenosine deaminase 2.	Uridine phosphorylase 1.	0.543
APRT	ADA2	ENSFCAP00000033614	ENSFCAP00000028652	Adenine phosphoribosyltransferase.	Adenosine deaminase 2.	0.760
APRT	CMPK1	ENSFCAP00000033614	ENSFCAP00000054095	Adenine phosphoribosyltransferase.	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	0.542
APRT	DCK	ENSFCAP00000033614	ENSFCAP00000020325	Adenine phosphoribosyltransferase.	Deoxycytidine kinase.	0.958
APRT	NT5C	ENSFCAP00000033614	ENSFCAP00000032366	Adenine phosphoribosyltransferase.	5', 3'-nucleotidase, cytosolic.	0.900
APRT	NT5C1A	ENSFCAP00000033614	ENSFCAP00000005600	Adenine phosphoribosyltransferase.	5'-nucleotidase, cytosolic IA.	0.936
APRT	NT5C2	ENSFCAP00000033614	ENSFCAP00000026132	Adenine phosphoribosyltransferase.	5'-nucleotidase, cytosolic II.	0.900
APRT	NT5C3B	ENSFCAP00000033614	ENSFCAP00000023807	Adenine phosphoribosyltransferase.	5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family.	0.941
APRT	NT5E	ENSFCAP00000033614	ENSFCAP00000060576	Adenine phosphoribosyltransferase.	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.	0.947
APRT	NT5M	ENSFCAP00000033614	ENSFCAP00000049088	Adenine phosphoribosyltransferase.	5',3'-nucleotidase, mitochondrial.	0.900