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NPR1 NPR1 NPR3 NPR3 GUCA2A GUCA2A NPPC NPPC M3X2R5_FELCA M3X2R5_FELCA GUCY2C GUCY2C PDE5A PDE5A PDE2A PDE2A NPPA NPPA GUCA2B GUCA2B NPR2 NPR2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NPR1Guanylate cyclase. (1063 aa)
NPR3Natriuretic peptide receptor 3. (537 aa)
GUCA2AGuanylate cyclase activator 2A. (111 aa)
NPPCNatriuretic peptide C. (193 aa)
M3X2R5_FELCAGuanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (170 aa)
GUCY2CGuanylate cyclase. (1073 aa)
PDE5APhosphodiesterase. (865 aa)
PDE2APhosphodiesterase. (942 aa)
NPPAAtrial natriuretic factor; Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3 (By similarity); Belongs to the natriuretic peptide family. (204 aa)
GUCA2BGuanylate cyclase activator 2B. (202 aa)
NPR2Guanylate cyclase. (1057 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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