STRINGSTRING
ENSFCAP00000044926 ENSFCAP00000044926 PRKN PRKN PINK1 PINK1 GBA GBA ATG4B ATG4B ATG4D ATG4D MAP1LC3B MAP1LC3B TIGAR TIGAR MAP1LC3A MAP1LC3A TP53 TP53 OGT OGT SPATA33 SPATA33 ENSFCAP00000041779 ENSFCAP00000041779 ARFIP2 ARFIP2 BECN1 BECN1 AMBRA1 AMBRA1 ATG13 ATG13 SQSTM1 SQSTM1 ATG14 ATG14 PHB2 PHB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSFCAP00000044926Uncharacterized protein. (107 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (462 aa)
PINK1PTEN induced kinase 1. (581 aa)
GBAGlucosylceramidase. (536 aa)
ATG4BCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (578 aa)
ATG4DCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (475 aa)
MAP1LC3BUncharacterized protein. (309 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (428 aa)
MAP1LC3AMicrotubule associated protein 1 light chain 3 alpha. (121 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (518 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa)
SPATA33Uncharacterized protein. (96 aa)
ENSFCAP00000041779Uncharacterized protein. (112 aa)
ARFIP2ADP ribosylation factor interacting protein 2. (374 aa)
BECN1Beclin 1. (448 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1301 aa)
ATG13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (550 aa)
SQSTM1Sequestosome 1. (443 aa)
ATG14Autophagy related 14. (510 aa)
PHB2Prohibitin. (299 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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