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| | USF1 | Upstream transcription factor 1. (444 aa) |
| | AJUBA | Ajuba LIM protein. (548 aa) |
| | NARF | Nuclear prelamin A recognition factor; Belongs to the NARF family. (456 aa) |
| | EPO | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. (192 aa) |
| | LOXL3 | Lysyl oxidase like 3. (974 aa) |
| | KCNMA1 | Potassium calcium-activated channel subfamily M alpha 1. (1288 aa) |
| | KCND2 | Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (630 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (419 aa) |
| | CIAO3 | Cytosolic iron-sulfur assembly component 3; Belongs to the NARF family. (476 aa) |
| | HMOX1 | Heme oxygenase 1. (404 aa) |
| | BNIP3 | BCL2 interacting protein 3. (187 aa) |
| | NOL3 | Nucleolar protein 3. (218 aa) |
| | FNDC1 | Fibronectin type III domain containing 1. (1886 aa) |
| | SUV39H1 | Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (498 aa) |
| | FAM162A | Family with sequence similarity 162 member A. (167 aa) |
| | TM9SF4 | Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (654 aa) |
| | RNASE4 | Ribonuclease A family member 4; Belongs to the pancreatic ribonuclease family. (189 aa) |
| | ALKBH5 | AlkB homolog 5, RNA demethylase. (414 aa) |
| | RYR1 | Ryanodine receptor 1. (5041 aa) |
| | ADA | Adenosine deaminase. (431 aa) |
| | SIRT2 | Sirtuin 2. (497 aa) |
| | ENSFCAP00000056299 | Uncharacterized protein; Belongs to the complex I LYR family. (70 aa) |
| | NF1 | Neurofibromin 1. (2856 aa) |
| | RYR2 | Ryanodine receptor 2. (4967 aa) |
| | KCND1 | Potassium voltage-gated channel subfamily D member 1; Belongs to the potassium channel family. (652 aa) |
| | CBFA2T3 | CBFA2/RUNX1 partner transcriptional co-repressor 3. (758 aa) |
| | HILPDA | Uncharacterized protein. (160 aa) |
| | HIF3A | Hypoxia inducible factor 3 subunit alpha. (794 aa) |
| | NKX3-1 | NK3 homeobox 1. (231 aa) |
| | SOD3 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (246 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (450 aa) |
| | TIGAR | TP53 induced glycolysis regulatory phosphatase. (428 aa) |
| | PMAIP1 | Phorbol-12-myristate-13-acetate-induced protein 1. (54 aa) |
| | MECP2 | Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa) |
| | MYOCD | Myocardin. (962 aa) |
| | MGARP | Mitochondria localized glutamic acid rich protein. (241 aa) |
| | ENSFCAP00000048958 | BHLH domain-containing protein. (109 aa) |
| | CHRNA7 | Uncharacterized protein. (499 aa) |
| | BAD | BCL2 associated agonist of cell death. (273 aa) |
| | TBL2 | Transducin beta like 2. (442 aa) |
| | BBC3 | Uncharacterized protein. (193 aa) |
| | PGF | Placental growth factor; Belongs to the PDGF/VEGF growth factor family. (170 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (518 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (439 aa) |
| | EGLN3 | Egl-9 family hypoxia inducible factor 3. (239 aa) |
| | PLAU | Plasminogen activator, urokinase. (516 aa) |
| | STOX1 | Storkhead box 1. (878 aa) |
| | ARNT2 | Aryl hydrocarbon receptor nuclear translocator 2. (717 aa) |
| | P2RX2 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (459 aa) |
| | REST | RE1 silencing transcription factor. (1045 aa) |
| | BACH1 | BTB domain and CNC homolog 1. (748 aa) |
| | EDNRA | Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa) |
| | RORA | RAR related orphan receptor A. (523 aa) |
| | TH | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (557 aa) |
| | NDNF | Neuron derived neurotrophic factor. (568 aa) |
| | ADAM8 | ADAM metallopeptidase domain 8. (872 aa) |
| | PTGIS | Prostacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (500 aa) |
| | ARNT | Aryl hydrocarbon receptor nuclear translocator. (790 aa) |
| | PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa) |
| | EGLN2 | Egl-9 family hypoxia inducible factor 2. (424 aa) |
| | SFRP1 | Secreted frizzled related protein 1. (314 aa) |
| | PLAT | Plasminogen activator; Belongs to the peptidase S1 family. (563 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (457 aa) |
| | HIF1AN | Hypoxia inducible factor 1 subunit alpha inhibitor. (349 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | BMP2 | Bone morphogenetic protein 2. (395 aa) |
| | WTIP | WT1 interacting protein. (433 aa) |
| | AQP3 | Aquaporin 3 (Gill blood group); Belongs to the MIP/aquaporin (TC 1.A.8) family. (292 aa) |
| | AQP1 | Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (310 aa) |
| | CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) |
| | NDRG1 | N-myc downstream regulated 1. (384 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (543 aa) |
| | SIRT1 | Sirtuin 1. (745 aa) |
| | PPARD | Peroxisome proliferator activated receptor delta. (464 aa) |
| | WDR83 | WD repeat domain 83. (315 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as a ubiquitin ligase E3 toward itself and ARRB1. Permits the nuclear export of p53/TP53. Promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma RB1 protein. Inhibits DAXX-mediated apoptosis by inducing its ubiquitination and degradation. Component of the TRIM28/KAP1-MDM2-p53/TP53 [...] (712 aa) |
| | PDK1 | Protein-serine/threonine kinase. (449 aa) |
| | SUV39H2 | Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (408 aa) |
| | P4HB | Protein disulfide-isomerase. (510 aa) |
| | ZFP36L1 | ZFP36 ring finger protein like 1. (338 aa) |
| | GATA6 | GATA binding protein 6. (646 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (504 aa) |
| | CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa) |
| | PIN1 | Peptidyl-prolyl cis-trans isomerase. (163 aa) |
| | NOP53 | NOP53 ribosome biogenesis factor. (485 aa) |
| | VASN | Vasorin. (692 aa) |
| | NR4A2 | Nuclear receptor subfamily 4 group A member 2. (598 aa) |
| | LMNA | Lamin A/C; Belongs to the intermediate filament family. (664 aa) |
| | LONP1 | Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...] (960 aa) |
| | NFE2L2 | Nuclear factor, erythroid 2 like 2. (606 aa) |
| | HMOX2 | Heme oxygenase 2. (316 aa) |
| | LOXL2 | Lysyl oxidase like 2. (773 aa) |
| | EPAS1 | Endothelial PAS domain protein 1. (872 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) |
| | EDN1 | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. (201 aa) |
| | SCAP | SREBF chaperone. (1278 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | ADO | 2-aminoethanethiol dioxygenase. (270 aa) |
| | CRYAB | Crystallin alpha B; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (175 aa) |
| | MIEF1 | Mitochondrial elongation factor 1. (463 aa) |
| | CHRNA4 | Cholinergic receptor nicotinic alpha 4 subunit. (633 aa) |
| | EGLN1 | Uncharacterized protein. (439 aa) |
| | DDIT4 | DNA damage inducible transcript 4. (231 aa) |
| | SRF | Serum response factor. (512 aa) |
| | LIMD1 | LIM domains containing 1. (673 aa) |
| | NOTCH1 | Notch receptor 1. (2543 aa) |
| | PLOD2 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2. (759 aa) |
| | SLC2A8 | Solute carrier family 2 member 8. (315 aa) |
| | NOS1 | Nitric oxide synthase 1. (1462 aa) |
| | NPEPPS | Aminopeptidase. (919 aa) |
| | ANGPT4 | Angiopoietin 4. (499 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2590 aa) |
| | PLOD1 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1. (727 aa) |
| | PINK1 | PTEN induced kinase 1. (581 aa) |
| | HP1BP3 | Heterochromatin protein 1 binding protein 3. (553 aa) |
| | ALAS2 | 5-aminolevulinate synthase. (633 aa) |
| | HYOU1 | Hypoxia up-regulated 1. (999 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2757 aa) |
| | KCND3 | Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (655 aa) |
| | PML | Promyelocytic leukemia. (876 aa) |
| | KLHL17 | Pleckstrin homology domain containing N1. (715 aa) |
| | HIF1A | Hypoxia inducible factor 1 subunit alpha. (825 aa) |
| | SLC11A2 | Solute carrier family 11 member 2. (656 aa) |
| | AGER | Advanced glycosylation end-product specific receptor. (492 aa) |
| | EP300 | E1A binding protein p300. (2425 aa) |
| | P2RX3 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (475 aa) |
| | VEGFB | Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (207 aa) |
| | CPEB2 | Cytoplasmic polyadenylation element binding protein 2. (1045 aa) |
