16 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSFCAP00000046406	MHC_I-like_Ag-recog domain-containing protein. (242 aa)
	PTPRC	Protein tyrosine phosphatase receptor type C. (1299 aa)
	LOC105260178	Ig-like domain-containing protein. (357 aa)
	PVR	PVR cell adhesion molecule. (380 aa)
	CD1B	CD1b molecule. (332 aa)
	IL12A	Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (222 aa)
	IL23A	Interleukin 23 subunit alpha. (196 aa)
	FADD	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (215 aa)
	B2M	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). (118 aa)
	M3X1V3_FELCA	Ig-like domain-containing protein. (313 aa)
	CD1E	CD1e molecule. (419 aa)
	IL12B	Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. (359 aa)
	LOC101089770	Uncharacterized protein. (715 aa)
	FAM49B	Family with sequence similarity 49 member B. (378 aa)
	STX7	Syntaxin 7; Belongs to the syntaxin family. (261 aa)
	LOC111556311	Uncharacterized protein. (857 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B2M	CD1B	ENSFCAP00000011347	ENSFCAP00000008015	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	CD1b molecule.	0.829
B2M	CD1E	ENSFCAP00000011347	ENSFCAP00000026353	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	CD1e molecule.	0.829
B2M	ENSFCAP00000046406	ENSFCAP00000011347	ENSFCAP00000046406	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	MHC_I-like_Ag-recog domain-containing protein.	0.829
B2M	LOC101089770	ENSFCAP00000011347	ENSFCAP00000035093	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Uncharacterized protein.	0.573
B2M	LOC105260178	ENSFCAP00000011347	ENSFCAP00000062064	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Ig-like domain-containing protein.	0.669
B2M	LOC111556311	ENSFCAP00000011347	ENSFCAP00000043207	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Uncharacterized protein.	0.573
B2M	M3X1V3_FELCA	ENSFCAP00000011347	ENSFCAP00000020598	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Ig-like domain-containing protein.	0.669
CD1B	B2M	ENSFCAP00000008015	ENSFCAP00000011347	CD1b molecule.	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	0.829
CD1E	B2M	ENSFCAP00000026353	ENSFCAP00000011347	CD1e molecule.	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	0.829
ENSFCAP00000046406	B2M	ENSFCAP00000046406	ENSFCAP00000011347	MHC_I-like_Ag-recog domain-containing protein.	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	0.829
IL12A	IL12B	ENSFCAP00000010340	ENSFCAP00000026531	Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.	Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family.	0.900
IL12A	IL23A	ENSFCAP00000010340	ENSFCAP00000011154	Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.	Interleukin 23 subunit alpha.	0.414
IL12B	IL12A	ENSFCAP00000026531	ENSFCAP00000010340	Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family.	Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.	0.900
IL12B	IL23A	ENSFCAP00000026531	ENSFCAP00000011154	Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family.	Interleukin 23 subunit alpha.	0.621
IL23A	IL12A	ENSFCAP00000011154	ENSFCAP00000010340	Interleukin 23 subunit alpha.	Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.	0.414
IL23A	IL12B	ENSFCAP00000011154	ENSFCAP00000026531	Interleukin 23 subunit alpha.	Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family.	0.621
LOC101089770	B2M	ENSFCAP00000035093	ENSFCAP00000011347	Uncharacterized protein.	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	0.573
LOC101089770	LOC111556311	ENSFCAP00000035093	ENSFCAP00000043207	Uncharacterized protein.	Uncharacterized protein.	0.900
LOC105260178	B2M	ENSFCAP00000062064	ENSFCAP00000011347	Ig-like domain-containing protein.	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	0.669
LOC111556311	B2M	ENSFCAP00000043207	ENSFCAP00000011347	Uncharacterized protein.	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	0.573