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SLC39A14 SLC39A14 HIF1A HIF1A IFT80 IFT80 TGFB1 TGFB1 ACCS ACCS CYTL1 CYTL1 RUNX1 RUNX1 GPLD1 GPLD1 GLI3 GLI3 NPPC NPPC COL2A1 COL2A1 BMPR2 BMPR2 COL3A1 COL3A1 ECM1 ECM1 MATN1 MATN1 OSR1 OSR1 TRIP11 TRIP11 MEF2D MEF2D TWSG1 TWSG1 FGF9 FGF9 ATF2 ATF2 MUSTN1 MUSTN1 AXIN2 AXIN2 BMPR1A BMPR1A RB1 RB1 SNX19 SNX19 RUNX3 RUNX3 SULF1 SULF1 PTH1R PTH1R CHST11 CHST11 MEF2C MEF2C BMP2 BMP2 MEX3C MEX3C GDF5 GDF5 HOXA11 HOXA11 BMPR1B BMPR1B SFRP2 SFRP2 IMPAD1 IMPAD1 OSR2 OSR2 HMGA2 HMGA2 WNT10B WNT10B SERPINH1 SERPINH1 EXT1 EXT1 WNT2B WNT2B SOX9 SOX9 FGF18 FGF18 RUNX2 RUNX2 LTBP3 LTBP3 RARG RARG BMP4 BMP4 CCN2 CCN2 COMP COMP NFIB NFIB CCN3 CCN3 ARID5A ARID5A ANXA6 ANXA6 SULF2 SULF2 CREB3L2 CREB3L2 SMPD3 SMPD3 SCUBE2 SCUBE2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SLC39A14Solute carrier family 39 member 14. (491 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (825 aa)
IFT80Intraflagellar transport 80. (777 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
ACCSExostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (863 aa)
CYTL1Cytokine like 1. (135 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (493 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (873 aa)
GLI3GLI family zinc finger 3. (1578 aa)
NPPCNatriuretic peptide C. (193 aa)
COL2A1Collagen type II alpha 1 chain. (1486 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
ECM1Extracellular matrix protein 1. (562 aa)
MATN1Matrilin 1. (539 aa)
OSR1Odd-skipped related transcription factor 1. (267 aa)
TRIP11Thyroid hormone receptor interactor 11. (1978 aa)
MEF2DMyocyte enhancer factor 2D. (519 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (223 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (504 aa)
MUSTN1Uncharacterized protein. (86 aa)
AXIN2Axin 2. (841 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
RB1RB transcriptional corepressor 1. (930 aa)
SNX19Sorting nexin 19. (1000 aa)
RUNX3Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (426 aa)
SULF1Sulfatase 1. (1116 aa)
PTH1RParathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family. (590 aa)
CHST11Carbohydrate sulfotransferase. (395 aa)
MEF2CMADS-box domain-containing protein. (483 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
MEX3CMex-3 RNA binding family member C. (657 aa)
GDF5Growth differentiation factor 5. (499 aa)
HOXA11Homeobox A11. (327 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (588 aa)
SFRP2Secreted frizzled related protein 2. (385 aa)
IMPAD1Inositol monophosphatase domain containing 1. (360 aa)
OSR2Odd-skipped related transciption factor 2. (312 aa)
HMGA2Uncharacterized protein. (109 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
SERPINH1Serpin family H member 1; Belongs to the serpin family. (592 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
SOX9SRY-box transcription factor 9. (511 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (326 aa)
RUNX2RUNX family transcription factor 2. (584 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1302 aa)
RARGRetinoic acid receptor gamma. (459 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
CCN2Cellular communication network factor 2. (477 aa)
COMPCartilage oligomeric matrix protein. (804 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
CCN3Cellular communication network factor 3. (394 aa)
ARID5AAT-rich interaction domain 5A. (608 aa)
ANXA6Annexin. (723 aa)
SULF2Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. (893 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (536 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (674 aa)
SCUBE2Signal peptide, CUB domain and EGF like domain containing 2. (1024 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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