STRINGSTRING
EZH2 EZH2 NRIP1 NRIP1 PHF12 PHF12 HDAC3 HDAC3 AJUBA AJUBA CREBBP CREBBP ZNF366 ZNF366 UXT UXT PARP14 PARP14 NCOR2 NCOR2 GPS2 GPS2 HSBP1L1 HSBP1L1 TLE7 TLE7 C1D C1D HIPK2 HIPK2 SIRT1 SIRT1 BCORL1 BCORL1 DMAP1 DMAP1 SMYD1 SMYD1 MIER2 MIER2 MLIP MLIP PEX14 PEX14 WTIP WTIP BCOR BCOR RUNX1T1 RUNX1T1 TLE5 TLE5 NCOR1 NCOR1 NR0B2 NR0B2 EID2 EID2 ENSFCAP00000035151 ENSFCAP00000035151 ZMYND8 ZMYND8 HDAC4 HDAC4 WWTR1 WWTR1 TRIB3 TRIB3 ENSFCAP00000036726 ENSFCAP00000036726 CASP8AP2 CASP8AP2 ELMSAN1 ELMSAN1 FAM162B FAM162B SAP18 SAP18 CDYL CDYL HDGF HDGF ENSFCAP00000039840 ENSFCAP00000039840 BTG2 BTG2 TBL1X TBL1X HMGA2 HMGA2 MIER3 MIER3 PHB PHB KCTD1 KCTD1 TLE4 TLE4 PRKN PRKN CBFA2T2 CBFA2T2 TLE2 TLE2 PARP15 PARP15 SCAI SCAI FOXP3 FOXP3 MED1 MED1 ZFPM2 ZFPM2 HDAC7 HDAC7 RERE RERE CYS1 CYS1 MIER1 MIER1 RYBP RYBP DNMT3B DNMT3B IRF2BPL IRF2BPL BASP1 BASP1 ZFPM1 ZFPM1 MECP2 MECP2 YAP1 YAP1 ENSFCAP00000049956 ENSFCAP00000049956 SIRT6 SIRT6 DAXX-2 DAXX-2 RBFOX2 RBFOX2 CDYL2 CDYL2 MTA1 MTA1 IRF2BP2 IRF2BP2 CCND1 CCND1 CTBP2 CTBP2 TSG101 TSG101 PBXIP1 PBXIP1 YAF2 YAF2 JAZF1 JAZF1 TOB1 TOB1 LOC101083323 LOC101083323 EID1 EID1 PRMT5 PRMT5 ENSFCAP00000053370 ENSFCAP00000053370 TLE3 TLE3 CBFA2T3 CBFA2T3 COPS2 COPS2 RIOX2 RIOX2 CCAR1 CCAR1 HNRNPU HNRNPU KMT5A KMT5A SIRT7 SIRT7 N4BP2L2 N4BP2L2 ARID5A ARID5A ELANE ELANE ZNF541 ZNF541 HMGB1 HMGB1 ENSFCAP00000058884 ENSFCAP00000058884 C1QBP C1QBP SPEN SPEN CTBP1 CTBP1 FAM162A FAM162A TLE1 TLE1 TRIM28 TRIM28 ZNF653 ZNF653 DAXX DAXX SFMBT1 SFMBT1 TCF25 TCF25 TOB2 TOB2 NOC2L NOC2L RUVBL2 RUVBL2 TBL1XR1 TBL1XR1 MYBBP1A MYBBP1A SNW1 SNW1 SIN3B SIN3B BEND6 BEND6 CNOT7 CNOT7 PARP9 PARP9 DRAP1 DRAP1 URI1 URI1 BCL3 BCL3 LIMD1 LIMD1 CIR1 CIR1 CREG1 CREG1 ATF7IP ATF7IP GMNN GMNN RBBP8 RBBP8 SAP30 SAP30 NR0B1 NR0B1 DDX54 DDX54 M3WPU0_FELCA M3WPU0_FELCA PIAS4 PIAS4 ANKRD1 ANKRD1 CRYM CRYM PA2G4 PA2G4 LMCD1 LMCD1 RCOR2 RCOR2 TLE6 TLE6 KDM5B KDM5B NPAT NPAT LOC101087446 LOC101087446 SIN3A SIN3A RCOR3 RCOR3 CITED2 CITED2 ATN1 ATN1 TRERF1 TRERF1 SFMBT2 SFMBT2 RCOR1 RCOR1 FHL2 FHL2 BRD7 BRD7 MTA2 MTA2 MTA3 MTA3 ZNF451 ZNF451
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (460 aa)
NRIP1Nuclear receptor interacting protein 1. (1155 aa)
PHF12PHD finger protein 12. (1004 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
AJUBAAjuba LIM protein. (548 aa)
CREBBPCREB binding protein. (2444 aa)
ZNF366Zinc finger protein 366. (845 aa)
UXTUbiquitously expressed prefoldin like chaperone. (170 aa)
PARP14Poly [ADP-ribose] polymerase. (1802 aa)
NCOR2Nuclear receptor corepressor 2. (2458 aa)
GPS2Uncharacterized protein. (327 aa)
HSBP1L1Heat shock factor binding protein 1 like 1. (85 aa)
TLE7TLE family member 7. (437 aa)
C1DC1D nuclear receptor corepressor. (178 aa)
HIPK2Homeodomain interacting protein kinase 2. (1222 aa)
SIRT1Sirtuin 1. (745 aa)
BCORL1BCL6 corepressor like 1. (1786 aa)
DMAP1DNA methyltransferase 1 associated protein 1. (663 aa)
SMYD1SET and MYND domain containing 1. (490 aa)
MIER2MIER family member 2. (560 aa)
MLIPMuscular LMNA interacting protein. (996 aa)
PEX14Peroxisomal biogenesis factor 14. (373 aa)
WTIPWT1 interacting protein. (433 aa)
BCORBCL6 corepressor. (1802 aa)
RUNX1T1RUNX1 partner transcriptional co-repressor 1. (615 aa)
TLE5TLE family member 5, transcriptional modulator. (316 aa)
NCOR1Nuclear receptor corepressor 1. (2515 aa)
NR0B2Nuclear receptor subfamily 0 group B member 2. (279 aa)
EID2EP300 interacting inhibitor of differentiation 2. (195 aa)
ENSFCAP00000035151Uncharacterized protein. (162 aa)
ZMYND8Zinc finger MYND-type containing 8. (1224 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1083 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
TRIB3Tribbles pseudokinase 3. (357 aa)
ENSFCAP00000036726Uncharacterized protein. (182 aa)
CASP8AP2Caspase 8 associated protein 2. (1779 aa)
ELMSAN1ELM2 and Myb/SANT domain containing 1. (1098 aa)
FAM162BFamily with sequence similarity 162 member B. (161 aa)
SAP18Sin3A associated protein 18. (200 aa)
CDYLChromodomain Y like. (616 aa)
HDGFHeparin binding growth factor. (282 aa)
ENSFCAP00000039840Uncharacterized protein. (76 aa)
BTG2BTG anti-proliferation factor 2. (162 aa)
TBL1XUncharacterized protein. (527 aa)
HMGA2Uncharacterized protein. (109 aa)
MIER3MIER family member 3. (558 aa)
PHBProhibitin. (272 aa)
KCTD1Potassium channel tetramerization domain containing 1. (865 aa)
TLE4TLE family member 4, transcriptional corepressor. (805 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (462 aa)
CBFA2T2CBFA2/RUNX1 partner transcriptional co-repressor 2. (595 aa)
TLE2TLE family member 2, transcriptional corepressor. (772 aa)
PARP15Poly [ADP-ribose] polymerase. (684 aa)
SCAIProtein SCAI; Tumor suppressor which functions to suppress MRTFA-induced SRF transcriptional activity. (606 aa)
FOXP3Forkhead box P3. (501 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1583 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1151 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1070 aa)
REREArginine-glutamic acid dipeptide repeats. (1547 aa)
CYS1Cystin 1. (168 aa)
MIER1MIER1 transcriptional regulator. (637 aa)
RYBPRING1 and YY1 binding protein. (228 aa)
DNMT3BDNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (856 aa)
IRF2BPLInterferon regulatory factor 2 binding protein like. (789 aa)
BASP1Uncharacterized protein. (106 aa)
ZFPM1Zinc finger protein, FOG family member 1. (992 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
YAP1Yes associated protein 1. (498 aa)
ENSFCAP00000049956Uncharacterized protein. (78 aa)
SIRT6Sirtuin 6. (412 aa)
DAXX-2Daxx domain-containing protein. (769 aa)
RBFOX2RNA binding fox-1 homolog 2. (484 aa)
CDYL2Chromodomain Y like 2. (514 aa)
MTA1Metastasis associated 1. (719 aa)
IRF2BP2Interferon regulatory factor 2 binding protein 2. (575 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (312 aa)
CTBP2C-terminal binding protein 2. (977 aa)
TSG101Tumor susceptibility 101. (400 aa)
PBXIP1PBX homeobox interacting protein 1. (684 aa)
YAF2YY1 associated factor 2. (279 aa)
JAZF1JAZF zinc finger 1. (250 aa)
TOB1Transducer of ERBB2, 1. (345 aa)
LOC101083323KRAB-related domain-containing protein. (188 aa)
EID1Uncharacterized protein. (191 aa)
PRMT5Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (652 aa)
ENSFCAP00000053370Uncharacterized protein. (87 aa)
TLE3TLE family member 3, transcriptional corepressor. (778 aa)
CBFA2T3CBFA2/RUNX1 partner transcriptional co-repressor 3. (758 aa)
COPS2COP9 signalosome subunit 2. (471 aa)
RIOX2Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (523 aa)
CCAR1Cell division cycle and apoptosis regulator 1. (1151 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (899 aa)
KMT5ALysine methyltransferase 5A. (500 aa)
SIRT7Sirtuin 7. (461 aa)
N4BP2L2Uncharacterized protein. (1219 aa)
ARID5AAT-rich interaction domain 5A. (608 aa)
ELANEElastase, neutrophil expressed; Belongs to the peptidase S1 family. (339 aa)
ZNF541Zinc finger protein 541. (1368 aa)
HMGB1Uncharacterized protein. (233 aa)
ENSFCAP00000058884Protein kinase domain-containing protein. (375 aa)
C1QBPComplement C1q binding protein. (314 aa)
SPENSpen family transcriptional repressor. (3678 aa)
CTBP1C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (467 aa)
FAM162AFamily with sequence similarity 162 member A. (167 aa)
TLE1TLE family member 1, transcriptional corepressor. (837 aa)
TRIM28Tripartite motif containing 28. (821 aa)
ZNF653Zinc finger protein 653. (616 aa)
DAXXDeath domain associated protein. (748 aa)
SFMBT1Scm like with four mbt domains 1. (866 aa)
TCF25Transcription factor 25. (672 aa)
TOB2Transducer of ERBB2, 2. (335 aa)
NOC2LNOC2 like nucleolar associated transcriptional repressor. (749 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
TBL1XR1WD_REPEATS_REGION domain-containing protein. (534 aa)
MYBBP1AMYB binding protein 1a. (1468 aa)
SNW1SNW domain containing 1. (570 aa)
SIN3BSIN3 transcription regulator family member B. (1123 aa)
BEND6BEN domain containing 6. (279 aa)
CNOT7CCR4-NOT transcription complex subunit 7. (285 aa)
PARP9Poly(ADP-ribose) polymerase family member 9. (828 aa)
DRAP1DR1 associated protein 1. (212 aa)
URI1URI1 prefoldin like chaperone. (533 aa)
BCL3BCL3 transcription coactivator. (454 aa)
LIMD1LIM domains containing 1. (673 aa)
CIR1Corepressor interacting with RBPJ, 1. (471 aa)
CREG1Cellular repressor of E1A stimulated genes 1; Belongs to the CREG family. (238 aa)
ATF7IPActivating transcription factor 7 interacting protein. (1262 aa)
GMNNGeminin DNA replication inhibitor. (210 aa)
RBBP8RB binding protein 8, endonuclease. (864 aa)
SAP30Sin3A associated protein 30. (221 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1. (471 aa)
DDX54ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (877 aa)
M3WPU0_FELCAUncharacterized protein. (162 aa)
PIAS4Protein inhibitor of activated STAT 4. (514 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
CRYMCrystallin mu. (314 aa)
PA2G4Proliferation-associated 2G4. (394 aa)
LMCD1LIM and cysteine rich domains 1. (362 aa)
RCOR2REST corepressor 2. (523 aa)
TLE6TLE family member 6, subcortical maternal complex member. (583 aa)
KDM5BLysine demethylase 5B. (1544 aa)
NPATNuclear protein, coactivator of histone transcription. (1442 aa)
LOC101087446Myb-like domain-containing protein. (2216 aa)
SIN3ASIN3 transcription regulator family member A. (1274 aa)
RCOR3REST corepressor 3. (555 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa)
ATN1Atrophin 1. (1193 aa)
TRERF1Transcriptional regulating factor 1. (1187 aa)
SFMBT2Scm like with four mbt domains 2. (894 aa)
RCOR1REST corepressor 1. (486 aa)
FHL2Four and a half LIM domains 2. (280 aa)
BRD7Bromodomain containing 7. (652 aa)
MTA2Metastasis associated 1 family member 2. (630 aa)
MTA3Metastasis associated 1 family member 3. (594 aa)
ZNF451Zinc finger protein 451. (1063 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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