56 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ESRRA	Estrogen related receptor alpha. (506 aa)
	NR2C1	Nuclear receptor subfamily 2 group C member 1. (605 aa)
	VDR	Vitamin D receptor. (441 aa)
	HNF4G	Hepatocyte nuclear factor 4 gamma. (462 aa)
	PPARD	Peroxisome proliferator activated receptor delta. (464 aa)
	NR1D2	Nuclear receptor subfamily 1 group D member 2. (576 aa)
	THRB	Thyroid hormone receptor beta. (476 aa)
	RORB	RAR related orphan receptor B. (470 aa)
	ESR2	Estrogen receptor 2. (574 aa)
	LOC101085801	Uncharacterized protein. (467 aa)
	NR2F2	Nuclear receptor subfamily 2 group F member 2. (463 aa)
	ENSFCAP00000045932	Uncharacterized protein. (123 aa)
	NR2E3	Nuclear receptor subfamily 2 group E member 3. (322 aa)
	NR4A3	Nuclear receptor subfamily 4 group A member 3. (651 aa)
	ENSFCAP00000048958	BHLH domain-containing protein. (109 aa)
	NR5A1	Nuclear receptor subfamily 5 group A member 1. (461 aa)
	RXRA	Retinoid X receptor alpha. (654 aa)
	PGR	Progesterone receptor. (932 aa)
	RORA	RAR related orphan receptor A. (523 aa)
	ARNT	Aryl hydrocarbon receptor nuclear translocator. (790 aa)
	RARA	Retinoic acid receptor alpha. (462 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
	RARG	Retinoic acid receptor gamma. (459 aa)
	NR2F1	Nuclear receptor subfamily 2 group F member 1. (453 aa)
	NR1H3	Nuclear receptor subfamily 1 group H member 3. (498 aa)
	NKX3-1	NK3 homeobox 1. (231 aa)
	ENSFCAP00000054841	BHLH domain-containing protein. (262 aa)
	RORC	RAR related orphan receptor C. (518 aa)
	ESRRG	Estrogen related receptor gamma. (506 aa)
	NR5A2	Nuclear receptor subfamily 5 group A member 2. (541 aa)
	NR4A1	Nuclear receptor subfamily 4 group A member 1. (598 aa)
	SMDT1	Single-pass membrane protein with aspartate rich tail 1. (107 aa)
	NR2F6	Nuclear receptor subfamily 2 group F member 6. (414 aa)
	STAT3	Signal transducer and activator of transcription. (770 aa)
	NR2E1	Nuclear receptor subfamily 2 group E member 1. (421 aa)
	NR2C2	Nuclear receptor subfamily 2 group C member 2. (596 aa)
	AHR	Uncharacterized protein. (849 aa)
	NR6A1	Nuclear receptor subfamily 6 group A member 1. (480 aa)
	PPARA	Peroxisome proliferator activated receptor alpha. (468 aa)
	NR1I2	Nuclear receptor subfamily 1 group I member 2. (434 aa)
	NR1H4	Nuclear receptor subfamily 1 group H member 4. (486 aa)
	LOC111556172	Uncharacterized protein. (536 aa)
	AR	Androgen receptor. (903 aa)
	HNF4A	Hepatocyte nuclear factor 4 alpha. (474 aa)
	NR1H2	Nuclear receptor subfamily 1 group H member 2. (457 aa)
	RARB	Retinoic acid receptor beta. (448 aa)
	RXRG	Retinoid X receptor gamma. (463 aa)
	NR4A2	Nuclear receptor subfamily 4 group A member 2. (598 aa)
	AHRR	Uncharacterized protein. (581 aa)
	NR1I3	Nuclear receptor subfamily 1 group I member 3. (423 aa)
	LOC101098124	Uncharacterized protein. (508 aa)
	NR3C1	Uncharacterized protein. (843 aa)
	ESR1	Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] (595 aa)
	ESRRB	Estrogen related receptor beta. (454 aa)
	ENSFCAP00000061174	Uncharacterized protein. (130 aa)
	LOC101101073	Uncharacterized protein. (971 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHR	AHRR	ENSFCAP00000004645	ENSFCAP00000014308	Uncharacterized protein.	Uncharacterized protein.	0.549
AHR	ARNT	ENSFCAP00000004645	ENSFCAP00000037022	Uncharacterized protein.	Aryl hydrocarbon receptor nuclear translocator.	0.987
AHR	ENSFCAP00000048958	ENSFCAP00000004645	ENSFCAP00000048958	Uncharacterized protein.	BHLH domain-containing protein.	0.940
AHR	ESR1	ENSFCAP00000004645	ENSFCAP00000020448	Uncharacterized protein.	Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]	0.444
AHRR	AHR	ENSFCAP00000014308	ENSFCAP00000004645	Uncharacterized protein.	Uncharacterized protein.	0.549
AHRR	ARNT	ENSFCAP00000014308	ENSFCAP00000037022	Uncharacterized protein.	Aryl hydrocarbon receptor nuclear translocator.	0.941
AHRR	ENSFCAP00000048958	ENSFCAP00000014308	ENSFCAP00000048958	Uncharacterized protein.	BHLH domain-containing protein.	0.724
AHRR	ENSFCAP00000054841	ENSFCAP00000014308	ENSFCAP00000054841	Uncharacterized protein.	BHLH domain-containing protein.	0.901
AR	ARNT	ENSFCAP00000006793	ENSFCAP00000037022	Androgen receptor.	Aryl hydrocarbon receptor nuclear translocator.	0.506
AR	ENSFCAP00000048958	ENSFCAP00000006793	ENSFCAP00000048958	Androgen receptor.	BHLH domain-containing protein.	0.439
AR	ESR1	ENSFCAP00000006793	ENSFCAP00000020448	Androgen receptor.	Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]	0.604
AR	NKX3-1	ENSFCAP00000006793	ENSFCAP00000053227	Androgen receptor.	NK3 homeobox 1.	0.570
AR	NR3C1	ENSFCAP00000006793	ENSFCAP00000019629	Androgen receptor.	Uncharacterized protein.	0.560
AR	PGR	ENSFCAP00000006793	ENSFCAP00000049487	Androgen receptor.	Progesterone receptor.	0.649
AR	STAT3	ENSFCAP00000006793	ENSFCAP00000001991	Androgen receptor.	Signal transducer and activator of transcription.	0.625
ARNT	AHR	ENSFCAP00000037022	ENSFCAP00000004645	Aryl hydrocarbon receptor nuclear translocator.	Uncharacterized protein.	0.987
ARNT	AHRR	ENSFCAP00000037022	ENSFCAP00000014308	Aryl hydrocarbon receptor nuclear translocator.	Uncharacterized protein.	0.941
ARNT	AR	ENSFCAP00000037022	ENSFCAP00000006793	Aryl hydrocarbon receptor nuclear translocator.	Androgen receptor.	0.506
ARNT	ENSFCAP00000054841	ENSFCAP00000037022	ENSFCAP00000054841	Aryl hydrocarbon receptor nuclear translocator.	BHLH domain-containing protein.	0.836
ARNT	ENSFCAP00000061174	ENSFCAP00000037022	ENSFCAP00000061174	Aryl hydrocarbon receptor nuclear translocator.	Uncharacterized protein.	0.518