92 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RUFY4	RUN and FYVE domain containing 4. (697 aa)
	MDP1	Uncharacterized protein. (164 aa)
	TECPR1	Tectonin beta-propeller repeat containing 1. (1201 aa)
	TEX264	Testis expressed 264, ER-phagy receptor. (313 aa)
	VPS11	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (941 aa)
	STING1	Stimulator of interferon genes. (377 aa)
	LRRK2	Leucine rich repeat kinase 2. (2527 aa)
	VPS16	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (839 aa)
	CD4H9orf72	Chromosome D4 C9orf72 homolog. (481 aa)
	WDFY3	WD repeat and FYVE domain containing 3. (3527 aa)
	CHMP2A	Charged multivesicular body protein 2A. (222 aa)
	VMP1	Vacuole membrane protein 1. (406 aa)
	ULK3	Unc-51 like kinase 3; Belongs to the protein kinase superfamily. (472 aa)
	LAMP2	Lysosomal associated membrane protein 2. (470 aa)
	HTT	Huntingtin. (3140 aa)
	TMEM150B	Transmembrane protein 150B. (234 aa)
	M3W4G5_FELCA	Uncharacterized protein. (120 aa)
	JMY	Junction mediating and regulatory protein, p53 cofactor. (988 aa)
	ATG14	Autophagy related 14. (510 aa)
	WASHC1	WASH complex subunit 1. (509 aa)
	GABARAP	GABA type A receptor-associated protein. (117 aa)
	WDR81	WD repeat domain 81. (1943 aa)
	SH3GLB1	SH3 domain containing GRB2 like, endophilin B1. (401 aa)
	MAP1LC3A	Microtubule associated protein 1 light chain 3 alpha. (121 aa)
	CHMP4C	Charged multivesicular body protein 4C. (237 aa)
	ATP6AP2	ATPase H+ transporting accessory protein 2. (351 aa)
	PIK3C3	Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
	PRKD1	Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (930 aa)
	TBC1D5	TBC1 domain family member 5. (826 aa)
	RAB7A	Uncharacterized protein. (207 aa)
	VPS33A	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (596 aa)
	TP53INP1	Tumor protein p53 inducible nuclear protein 1. (239 aa)
	M3WPJ7_FELCA	Uncharacterized protein. (188 aa)
	STX17	Syntaxin 17; Belongs to the syntaxin family. (302 aa)
	ZFYVE1	Zinc finger FYVE-type containing 1. (790 aa)
	SQSTM1	Sequestosome 1. (443 aa)
	ADPRHL1	ADP-ribosylhydrolase like 1. (354 aa)
	LAMP1	Lysosomal associated membrane protein 1. (422 aa)
	LOC101094500	Uncharacterized protein. (274 aa)
	ATG16L2	Autophagy related 16 like 2. (617 aa)
	ATG9B	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (920 aa)
	BECN1	Beclin 1. (448 aa)
	ATG16L1	Autophagy related 16 like 1. (623 aa)
	ATG9A	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (998 aa)
	ULK1	Unc-51 like autophagy activating kinase 1. (1113 aa)
	RB1CC1	RB1 inducible coiled-coil 1. (1593 aa)
	ATP13A2	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1161 aa)
	TBC1D25	TBC1 domain family member 25. (687 aa)
	GABARAPL2	GABA type A receptor associated protein like 2. (117 aa)
	ATG12	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
	HSPA8	Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family. (667 aa)
	RAB24	RAB24, member RAS oncogene family. (203 aa)
	LOC101095070	Uncharacterized protein. (141 aa)
	CHMP4A	Charged multivesicular body protein 4A. (220 aa)
	CHMP1A	Charged multivesicular body protein 1A. (196 aa)
	ENSFCAP00000033387	Uncharacterized protein. (491 aa)
	VTI1A	Vesicle transport through interaction with t-SNAREs 1A. (267 aa)
	PLEKHM1	Pleckstrin homology and RUN domain containing M1. (1066 aa)
	PIP4K2A	Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (421 aa)
	NBR1	NBR1 autophagy cargo receptor. (968 aa)
	TMEM230	Uncharacterized protein. (120 aa)
	CLN3	Battenin. (438 aa)
	ENSFCAP00000038726	Uncharacterized protein. (134 aa)
	TRIM21	Tripartite motif containing 21. (469 aa)
	NCOA4	Nuclear receptor coactivator 4. (613 aa)
	TP53INP2	Tumor protein p53 inducible nuclear protein 2. (221 aa)
	ENTPD4	Ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family. (632 aa)
	MAP1LC3C	Uncharacterized protein. (141 aa)
	ENSFCAP00000041779	Uncharacterized protein. (112 aa)
	TBC1D12	TBC1 domain family member 12. (762 aa)
	ENSFCAP00000044926	Uncharacterized protein. (107 aa)
	PIP4K2B	Phosphatidylinositol-5-phosphate 4-kinase type 2 beta. (416 aa)
	ATG5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	CHMP2B	Charged multivesicular body protein 2B. (227 aa)
	TM9SF1	Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (690 aa)
	CHMP5	Charged multivesicular body protein 5. (372 aa)
	GABARAPL1	GABA type A receptor associated protein like 1. (151 aa)
	FYCO1	FYVE and coiled-coil domain containing 1. (1459 aa)
	CHMP6	Charged multivesicular body protein 6. (263 aa)
	RUBCNL	Rubicon like autophagy enhancer. (677 aa)
	GAA	Glucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family. (1002 aa)
	MAP1LC3B	Uncharacterized protein. (309 aa)
	AUP1	AUP1 lipid droplet regulating VLDL assembly factor. (492 aa)
	OSBPL7	Oxysterol-binding protein; Belongs to the OSBP family. (956 aa)
	CHMP7	Charged multivesicular body protein 7. (456 aa)
	UBQLN4	Ubiquilin 4. (608 aa)
	UVRAG	UV radiation resistance associated. (718 aa)
	WIPI2	WD repeat domain, phosphoinositide interacting 2. (468 aa)
	WIPI1	WD repeat domain, phosphoinositide interacting 1. (470 aa)
	ATG4B	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (578 aa)
	PIP4K2C	Phosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (435 aa)
	CALCOCO2	Calcium binding and coiled-coil domain 2. (474 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG12	ATG14	ENSFCAP00000007041	ENSFCAP00000017368	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy related 14.	0.891
ATG12	ATG16L1	ENSFCAP00000007041	ENSFCAP00000010520	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy related 16 like 1.	0.999
ATG12	ATG16L2	ENSFCAP00000007041	ENSFCAP00000012237	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy related 16 like 2.	0.995
ATG12	ATG4B	ENSFCAP00000007041	ENSFCAP00000059680	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.803
ATG12	ATG5	ENSFCAP00000007041	ENSFCAP00000046882	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.999
ATG12	ATG9A	ENSFCAP00000007041	ENSFCAP00000010443	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.745
ATG12	ATG9B	ENSFCAP00000007041	ENSFCAP00000012236	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.614
ATG12	BECN1	ENSFCAP00000007041	ENSFCAP00000012183	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Beclin 1.	0.981
ATG12	CALCOCO2	ENSFCAP00000007041	ENSFCAP00000061183	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Calcium binding and coiled-coil domain 2.	0.479
ATG12	ENSFCAP00000041779	ENSFCAP00000007041	ENSFCAP00000041779	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Uncharacterized protein.	0.704
ATG12	ENSFCAP00000044926	ENSFCAP00000007041	ENSFCAP00000044926	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Uncharacterized protein.	0.704
ATG12	GABARAP	ENSFCAP00000007041	ENSFCAP00000022562	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	GABA type A receptor-associated protein.	0.983
ATG12	GABARAPL1	ENSFCAP00000007041	ENSFCAP00000048541	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	GABA type A receptor associated protein like 1.	0.976
ATG12	GABARAPL2	ENSFCAP00000007041	ENSFCAP00000007798	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	GABA type A receptor associated protein like 2.	0.988
ATG12	LAMP1	ENSFCAP00000007041	ENSFCAP00000013220	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Lysosomal associated membrane protein 1.	0.602
ATG12	LAMP2	ENSFCAP00000007041	ENSFCAP00000004187	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Lysosomal associated membrane protein 2.	0.527
ATG12	LOC101095070	ENSFCAP00000007041	ENSFCAP00000034687	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Uncharacterized protein.	0.657
ATG12	MAP1LC3A	ENSFCAP00000007041	ENSFCAP00000023860	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Microtubule associated protein 1 light chain 3 alpha.	0.818
ATG12	MAP1LC3B	ENSFCAP00000007041	ENSFCAP00000054052	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Uncharacterized protein.	0.704
ATG12	MAP1LC3C	ENSFCAP00000007041	ENSFCAP00000041324	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Uncharacterized protein.	0.791