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| | ACER2 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa) |
| | ASS1 | Argininosuccinate synthase 1. (412 aa) |
| | NOTCH1 | Notch receptor 1. (2543 aa) |
| | PLA2G2D | Phospholipase A(2). (145 aa) |
| | PTPN22 | Protein tyrosine phosphatase non-receptor type 22. (801 aa) |
| | PLXNA3 | Plexin A3. (1872 aa) |
| | CORO2B | Coronin; Belongs to the WD repeat coronin family. (501 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (556 aa) |
| | PODXL | Podocalyxin like. (594 aa) |
| | ANXA1 | Annexin. (407 aa) |
| | PLET1 | Uncharacterized protein. (278 aa) |
| | ENSFCAP00000060822 | Ig-like domain-containing protein. (252 aa) |
| | KANK1 | KN motif and ankyrin repeat domains 1. (1366 aa) |
| | CD86 | B-lymphocyte activation antigen B7-2 (CD86). (332 aa) |
| | JAG1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1287 aa) |
| | HMGB1 | Uncharacterized protein. (233 aa) |
| | ENSFCAP00000057918 | Uncharacterized protein. (293 aa) |
| | ENSFCAP00000057780 | Uncharacterized protein. (585 aa) |
| | LPXN | Leupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (387 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1299 aa) |
| | ADTRP | Androgen dependent TFPI regulating protein. (248 aa) |
| | NF1 | Neurofibromin 1. (2856 aa) |
| | MUC1 | Uncharacterized protein. (931 aa) |
| | PLXNB3 | Plexin B3. (2058 aa) |
| | ADAM15 | ADAM metallopeptidase domain 15. (869 aa) |
| | LOC101083890 | Ig-like domain-containing protein. (285 aa) |
| | VSIG4 | V-set and immunoglobulin domain containing 4. (404 aa) |
| | AJAP1 | Adherens junctions associated protein 1. (431 aa) |
| | TRPV4 | Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (963 aa) |
| | RIPOR2 | RHO family interacting cell polarization regulator 2. (1162 aa) |
| | OPRD1 | YTH N6-methyladenosine RNA binding protein 2. (600 aa) |
| | NDFIP1 | Nedd4 family interacting protein 1. (224 aa) |
| | PLXNA4 | Plexin A4. (1893 aa) |
| | BMP4 | Bone morphogenetic protein 4. (409 aa) |
| | LAX1 | Lymphocyte transmembrane adaptor 1. (402 aa) |
| | DLG1 | Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (939 aa) |
| | MUC21 | Epiglycanin_C domain-containing protein. (112 aa) |
| | CBLL1 | Cbl proto-oncogene like 1. (537 aa) |
| | FBLN1 | Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (705 aa) |
| | ARHGAP6 | Rho GTPase activating protein 6. (455 aa) |
| | IL1RN | Interleukin-1. (182 aa) |
| | CEBPB | CCAAT/enhancer-binding protein. (346 aa) |
| | PRKAR1A | Protein kinase cAMP-dependent type I regulatory subunit alpha. (569 aa) |
| | DUSP3 | Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa) |
| | DLG2 | Discs large MAGUK scaffold protein 2. (1012 aa) |
| | LOC101081130 | AIG1-type G domain-containing protein. (309 aa) |
| | LOC101100430 | Galectin. (138 aa) |
| | SOCS1 | Suppressor of cytokine signaling 1. (203 aa) |
| | RC3H1 | Ring finger and CCCH-type domains 1. (1133 aa) |
| | FGL1 | Fibrinogen like 1. (378 aa) |
| | DMTN | Dematin actin binding protein. (405 aa) |
| | ILDR2 | Immunoglobulin like domain containing receptor 2. (644 aa) |
| | RC3H2 | Ring finger and CCCH-type domains 2. (1132 aa) |
| | TIGIT | T cell immunoreceptor with Ig and ITIM domains. (312 aa) |
| | CBFB | Uncharacterized protein. (187 aa) |
| | FOXP3 | Forkhead box P3. (501 aa) |
| | PTPN2 | Tyrosine-protein phosphatase non-receptor type. (416 aa) |
| | SMAD7 | Mothers against decapentaplegic homolog. (426 aa) |
| | CYP1B1 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (553 aa) |
| | NCKAP1L | NCK associated protein 1 like. (1179 aa) |
| | EFNA5 | Ephrin A5; Belongs to the ephrin family. (228 aa) |
| | GLMN | Glomulin, FKBP associated protein. (600 aa) |
| | VTCN1 | V-set domain containing T cell activation inhibitor 1. (282 aa) |
| | CTLA4 | Cytotoxic T-lymphocyte associated protein 4. (268 aa) |
| | LOC101088701 | Ig-like domain-containing protein. (370 aa) |
| | RASA1 | RAS p21 protein activator 1. (1039 aa) |
| | ZNF703 | Zinc finger protein 703. (592 aa) |
| | FGL2 | Fibrinogen like 2. (440 aa) |
| | CD9 | CD9 antigen; Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion (By similarity). Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of the membrane required for the fusion (By similarity). In myoblasts, associates with CD81 and PTGFRN and inhibits myotube fusion during muscle regeneration (By similarity). In macrophages, associates with CD81 and beta-1 and beta-2 integrins, [...] (250 aa) |
| | PHLDB2 | Pleckstrin homology like domain family B member 2. (1247 aa) |
| | ACVRL1 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (517 aa) |
| | DLG5 | Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1921 aa) |
| | PLA2G2F | Phospholipase A(2). (211 aa) |
| | PLXNA2 | Plexin A2. (1911 aa) |
| | TNFRSF21 | TNF receptor superfamily member 21. (651 aa) |
| | PLXNC1 | Plexin C1. (1576 aa) |
| | NRARP | NOTCH regulated ankyrin repeat protein. (114 aa) |
| | HLX | H2.0 like homeobox. (569 aa) |
| | MYOC | Myocilin, C-terminal fragment; Secreted glycoprotein regulating the activation of different signaling pathways in adjacent cells to control different processes including cell adhesion, cell-matrix adhesion, cytoskeleton organization and cell migration. Promotes substrate adhesion, spreading and formation of focal contacts. Negatively regulates cell-matrix adhesion and stress fiber assembly through Rho protein signal transduction. Modulates the organization of actin cytoskeleton by stimulating the formation of stress fibers through interactions with components of Wnt signaling pathways. [...] (498 aa) |
| | CASP3 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. (302 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (540 aa) |
| | ITGB1BP1 | Integrin subunit beta 1 binding protein 1. (213 aa) |
| | BMP2 | Bone morphogenetic protein 2. (395 aa) |
| | PRNP | Major prion protein; Its primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as an agonist for ADGRG6 receptor. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro) (By similarity). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase deg [...] (260 aa) |
| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa) |
| | CASK | Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (935 aa) |
| | PRKG1 | cGMP-dependent protein kinase. (686 aa) |
| | FZD7 | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa) |
| | HAVCR2 | Hepatitis A virus cellular receptor 2. (280 aa) |
| | PELI1 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa) |
| | ACTN4 | Actinin alpha 4. (933 aa) |
| | CBLB | Cbl proto-oncogene B. (1182 aa) |
| | CORO1C | Coronin; Belongs to the WD repeat coronin family. (525 aa) |
| | SEMA6A | Semaphorin 6A; Belongs to the semaphorin family. (1047 aa) |
| | JAM3 | Junctional adhesion molecule 3. (310 aa) |
| | BMP6 | Bone morphogenetic protein 6. (502 aa) |
| | PAWR | Pro-apoptotic WT1 regulator. (347 aa) |
| | UBASH3B | Ubiquitin associated and SH3 domain containing B. (649 aa) |
| | GPNMB | Glycoprotein nmb. (568 aa) |
| | PRKAR1B | Protein kinase cAMP-dependent type I regulatory subunit beta. (378 aa) |
| | LOC101082108 | Ig-like domain-containing protein. (386 aa) |
| | TWSG1 | Twisted gastrulation BMP signaling modulator 1. (223 aa) |
| | PKHD1L1 | PKHD1 like 1. (4242 aa) |
| | IDO1 | Indoleamine 2,3-dioxygenase 1. (407 aa) |
| | SH2B3 | SH2B adaptor protein 3. (578 aa) |
| | CCL21 | C-C motif chemokine ligand 21. (134 aa) |
| | TMEM131L | Transmembrane 131 like. (1609 aa) |
| | SERPINE2 | Serpin family E member 2; Belongs to the serpin family. (484 aa) |
| | C1QTNF1 | C1q and TNF related 1. (279 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (134 aa) |
| | PLXNB1 | Plexin B1. (2135 aa) |
| | IL20RB | Interleukin 20 receptor subunit beta. (294 aa) |
| | CLEC4G | C-type lectin domain family 4 member G. (317 aa) |
| | ALOX12 | Arachidonate 12-lipoxygenase, 12S type. (664 aa) |
| | CRTAM | Cytotoxic and regulatory T cell molecule. (400 aa) |
| | SCRIB | Scribble planar cell polarity protein. (1637 aa) |
| | CHCHD6 | MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (2112 aa) |
| | SOCS5 | Suppressor of cytokine signaling 5. (536 aa) |
| | AKNA | AT-hook transcription factor. (1405 aa) |
| | PLXND1 | Plexin D1. (1927 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | RND1 | Rho family GTPase 1. (232 aa) |
| | MAD2L2 | Mitotic arrest deficient 2 like 2. (211 aa) |
| | APOD | Apolipoprotein D. (189 aa) |
| | MARCHF7 | Membrane associated ring-CH-type finger 7. (705 aa) |
| | SPINT2 | Serine peptidase inhibitor, Kunitz type 2. (252 aa) |
| | ADORA2A | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa) |
| | HFE | Homeostatic iron regulator; Belongs to the MHC class I family. (362 aa) |
| | BCL6 | BCL6 transcription repressor. (745 aa) |
| | LAG3 | Lymphocyte activating 3. (513 aa) |
| | TSPAN32 | Tetraspanin 32; Belongs to the tetraspanin (TM4SF) family. (289 aa) |
| | EPHA4 | EPH receptor A4. (986 aa) |
| | ZC3H8 | Zinc finger CCCH-type containing 8. (311 aa) |
| | C1QTNF6 | C1q and TNF related 6. (284 aa) |
| | ZC3H12A | Zinc finger CCCH-type containing 12A. (582 aa) |
| | ITCH | E3 ubiquitin-protein ligase. (862 aa) |
| | MAPK7 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (804 aa) |
| | CD274 | CD274 molecule. (297 aa) |
| | PDCD1LG2 | Programmed cell death 1 ligand 2. (302 aa) |
| | SOCS6 | Suppressor of cytokine signaling 6. (497 aa) |
| | LGALS9 | Galectin. (356 aa) |
| | ABCA12 | ATP binding cassette subfamily A member 12. (2595 aa) |
| | CD80 | B-lymphocyte activation antigen B7-1 (CD80). (292 aa) |
| | RCC2 | Regulator of chromosome condensation 2. (522 aa) |
| | ADAMTS18 | ADAM metallopeptidase with thrombospondin type 1 motif 18. (1221 aa) |
| | TBX21 | T-box transcription factor 21. (535 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (725 aa) |
| | THBS1 | Thrombospondin 1. (1170 aa) |
| | PLXNB2 | Plexin B2. (1841 aa) |
| | GLI3 | GLI family zinc finger 3. (1578 aa) |
| | LRRC32 | Leucine rich repeat containing 32. (663 aa) |
| | ATP5F1B | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (528 aa) |
| | VSIR | V-set immunoregulatory receptor. (311 aa) |
| | IRF1 | Interferon regulatory factor. (322 aa) |
| | IL10 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (178 aa) |
| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. (154 aa) |
| | HRG | Histidine rich glycoprotein. (536 aa) |
| | ADIPOQ | Adiponectin, C1Q and collagen domain containing. (283 aa) |
| | TBCD | Tubulin folding cofactor D. (1189 aa) |
| | ARG2 | Arginase. (354 aa) |
| | ANGPT2 | Angiopoietin 2. (494 aa) |
| | TNR | Tenascin R. (1358 aa) |
| | ERBB3 | ERBB3. (1339 aa) |
| | PAG1 | Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (434 aa) |
| | SPOCK1 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1. (441 aa) |
| | SNAI2 | Uncharacterized protein. (268 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | ZBTB7B | Uncharacterized protein. (540 aa) |
| | LRRC1 | Leucine rich repeat containing 1. (524 aa) |
| | CORO2A | Coronin; Belongs to the WD repeat coronin family. (515 aa) |
| | SEMA3E | Semaphorin 3E; Belongs to the semaphorin family. (775 aa) |
| | DEF6 | DEF6 guanine nucleotide exchange factor. (631 aa) |
| | IL2RA | Interleukin-2 receptor subunit alpha; Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. (275 aa) |
| | FOXJ1 | Forkhead box J1. (417 aa) |
| | TNFAIP8L2 | TNF alpha induced protein 8 like 2. (184 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | MAD1L1 | Mitotic arrest deficient 1 like 1. (916 aa) |
| | IHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa) |
| | AP1AR | Adaptor related protein complex 1 associated regulatory protein. (302 aa) |
| | PDE3B | Phosphodiesterase. (1122 aa) |
| | MYADM | Myeloid associated differentiation marker. (322 aa) |
| | HOXA7 | Homeobox A7. (234 aa) |
| | ABL1 | Tyrosine-protein kinase. (1150 aa) |
| | IFNB1 | Interferon beta; Has antiviral, antibacterial and anticancer activities. (186 aa) |
| | CDH13 | Cadherin 13. (713 aa) |
| | PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (615 aa) |
| | NF2 | Neurofibromin 2. (596 aa) |
| | SEMA4D | Semaphorin 4D; Belongs to the semaphorin family. (863 aa) |
| | PRKCD | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) |
| | MELTF | Melanotransferrin; Belongs to the transferrin family. (744 aa) |
| | SWAP70 | Switching B cell complex subunit SWAP70. (585 aa) |
| | SPRY4 | Sprouty RTK signaling antagonist 4. (321 aa) |
