STRINGSTRING
RAC3 RAC3 CSF1R CSF1R RPL24 RPL24 POU4F2 POU4F2 RYK RYK NTN3 NTN3 SEMA4A SEMA4A EMB EMB LAMA2 LAMA2 TRIO-2 TRIO-2 CHADL CHADL PLXNB3 PLXNB3 NFIB NFIB KALRN KALRN FLRT3 FLRT3 RAC2 RAC2 VSTM2L VSTM2L RELN RELN GAS1 GAS1 NTN1 NTN1 ETV4 ETV4 EFNA1 EFNA1 BSG BSG RAC1 RAC1 SMO SMO CXCL12 CXCL12 SEMA3B SEMA3B ENSFCAP00000060693 ENSFCAP00000060693 LAMA5 LAMA5 SEMA6B SEMA6B EFNB1 EFNB1 PLXNA3 PLXNA3 CNTN2 CNTN2 NPTN NPTN NRP1 NRP1 LRTM2 LRTM2 MYCBP2 MYCBP2 ENSFCAP00000003985 ENSFCAP00000003985 SEMA4D SEMA4D SLIT1 SLIT1 KLF7 KLF7 PLXNB1 PLXNB1 GFRA3 GFRA3 APP APP CHCHD6 CHCHD6 CNTN4 CNTN4 PLXND1 PLXND1 ISL2 ISL2 DRAXIN DRAXIN RHOG RHOG GDF7 GDF7 EFNA3 EFNA3 SEMA4C SEMA4C PLA2G10 PLA2G10 UNC5D UNC5D IGSF9 IGSF9 FOXG1 FOXG1 CHL1 CHL1 DAG1 DAG1 NCAM1 NCAM1 SEMA5B SEMA5B EPHA6 EPHA6 NRP2 NRP2 ARTN ARTN LHX3 LHX3 ENAH ENAH EFNA2 EFNA2 CNTN5 CNTN5 NOG NOG EFNB3 EFNB3 DRGX DRGX NGFR NGFR ARHGAP35 ARHGAP35 GATA3 GATA3 EXT1 EXT1 SEMA6C SEMA6C CDK5R2 CDK5R2 DLX5 DLX5 EFNA4 EFNA4 ROBO2 ROBO2 PTPRO PTPRO EPHB1 EPHB1 EFNA5 EFNA5 ARX ARX CRMP1 CRMP1 PALLD PALLD EDNRA EDNRA SEMA5A SEMA5A ROBO3 ROBO3 LHX2 LHX2 SEMA3F SEMA3F ALCAM ALCAM PAX6 PAX6 EPHA1 EPHA1 VASP VASP DVL1 DVL1 M3W868_FELCA M3W868_FELCA EPHA4 EPHA4 HOXA2 HOXA2 SEMA7A SEMA7A CDK5R1 CDK5R1 EGR2 EGR2 L1CAM L1CAM LAMA1 LAMA1 NKX2-2 NKX2-2 EPHB3 EPHB3 B3GNT2 B3GNT2 LAMA3 LAMA3 LAMB2 LAMB2 EPHA2 EPHA2 LAMC2 LAMC2 SLIT3 SLIT3 TTC8 TTC8 ISL1 ISL1 WNT3 WNT3 PLXNB2 PLXNB2 GLI3 GLI3 RHOH RHOH DCC DCC GBX1 GBX1 FEZF1 FEZF1 ROBO1 ROBO1 ECE1 ECE1 EDN1 EDN1 EFNB2 EFNB2 MYOT MYOT SEMA4G SEMA4G SEMA3G SEMA3G EPHA7 EPHA7 B4GAT1 B4GAT1 SEMA3E SEMA3E EVX1 EVX1 KIF5B KIF5B M3WUK9_FELCA M3WUK9_FELCA SEMA3C SEMA3C USP33 USP33 OTX2 OTX2 FLRT2 FLRT2 EPHA8 EPHA8 NTN5 NTN5 CDK5 CDK5 PKHD1L1 PKHD1L1 FZD3 FZD3 ENSFCAP00000023603 ENSFCAP00000023603 SEMA3D SEMA3D SEMA3A SEMA3A SEMA4B SEMA4B UNC5B UNC5B SEMA6A SEMA6A RTN4RL1 RTN4RL1 BOC BOC GAP43 GAP43 LRTM1 LRTM1 ARHGEF25 ARHGEF25 CRPPA CRPPA UNC5A UNC5A KIF5C KIF5C RTN4R RTN4R EPHA3 EPHA3 DPYSL5 DPYSL5 SMAD4 SMAD4 EPHA10 EPHA10 EPHB2 EPHB2 RNF165 RNF165 KIF5A KIF5A PLXNC1 PLXNC1 GDNF GDNF NKX2-1 NKX2-1 SEMA6D SEMA6D LHX4 LHX4 CNTN1 CNTN1 GBX2 GBX2 WNT3A WNT3A NEO1 NEO1 NEXN NEXN PLXNA2 PLXNA2 EPHA5 EPHA5 VAX1 VAX1 UNC5C UNC5C LHX9 LHX9 NFASC NFASC LGI1 LGI1 EPHB4 EPHB4 NRCAM NRCAM BMPR1B BMPR1B LHX1 LHX1 ATOH1 ATOH1 SLIT2 SLIT2 CNTN6 CNTN6 BCL11B BCL11B PLXNA4 PLXNA4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAC3Rac family small GTPase 3. (205 aa)
CSF1RMacrophage colony-stimulating factor 1 receptor; Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulat [...] (1213 aa)
RPL2460S ribosomal protein L24; Belongs to the eukaryotic ribosomal protein eL24 family. (157 aa)
POU4F2POU domain protein. (408 aa)
RYKReceptor like tyrosine kinase. (609 aa)
NTN3Netrin 3. (607 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (806 aa)
EMBUncharacterized protein. (473 aa)
LAMA2Laminin subunit alpha 2. (3125 aa)
TRIO-2Uncharacterized protein. (1847 aa)
CHADLChondroadherin like. (891 aa)
PLXNB3Plexin B3. (2058 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
KALRNKalirin RhoGEF kinase. (2987 aa)
FLRT3Fibronectin leucine rich transmembrane protein 3. (649 aa)
RAC2Rac family small GTPase 2. (234 aa)
VSTM2LV-set and transmembrane domain containing 2 like. (284 aa)
RELNReelin. (3460 aa)
GAS1Growth arrest specific 1. (369 aa)
NTN1Netrin 1. (715 aa)
ETV4ETS variant 4. (488 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (357 aa)
BSGBasigin. (356 aa)
RAC1Rac family small GTPase 1. (221 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (795 aa)
CXCL12Stromal cell-derived factor 1; Chemoattractant active on T-lymphocytes and monocytes but not neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. Also binds to atypical chemokine receptor ACKR3, which activates the beta-arrestin pathway and acts as a scavenger receptor for SDF-1. Acts as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the LYN kinase. Binds to the allosteric site (site 2) of integrins and activates integrins ITGAV:ITGB3, ITGA4 [...] (143 aa)
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (777 aa)
ENSFCAP00000060693TF_Otx domain-containing protein. (184 aa)
LAMA5Laminin subunit alpha 5. (3001 aa)
SEMA6BSemaphorin 6B; Belongs to the semaphorin family. (1296 aa)
EFNB1Ephrin B1. (427 aa)
PLXNA3Plexin A3. (1872 aa)
CNTN2Contactin 2. (1103 aa)
NPTNNeuroplastin. (446 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
LRTM2Leucine rich repeats and transmembrane domains 2. (370 aa)
MYCBP2MYC binding protein 2. (4675 aa)
ENSFCAP00000003985Uncharacterized protein. (184 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (863 aa)
SLIT1Slit guidance ligand 1. (1518 aa)
KLF7Kruppel like factor 7. (301 aa)
PLXNB1Plexin B1. (2135 aa)
GFRA3GDNF family receptor alpha 3. (395 aa)
APPAmyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...] (935 aa)
CHCHD6MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (2112 aa)
CNTN4Contactin 4. (1026 aa)
PLXND1Plexin D1. (1927 aa)
ISL2ISL LIM homeobox 2. (359 aa)
DRAXINDraxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (377 aa)
RHOGRas homolog family member G. (191 aa)
GDF7Growth differentiation factor 7. (455 aa)
EFNA3Ephrin RBD domain-containing protein; Belongs to the ephrin family. (237 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (1000 aa)
PLA2G10Phospholipase A(2). (162 aa)
UNC5DUnc-5 netrin receptor D. (958 aa)
IGSF9Uncharacterized protein. (1179 aa)
FOXG1Forkhead box G1. (483 aa)
CHL1Cell adhesion molecule L1 like. (1223 aa)
DAG1Peptidase S72 domain-containing protein. (892 aa)
NCAM1Neural cell adhesion molecule 1. (1135 aa)
SEMA5BSemaphorin 5B. (1100 aa)
EPHA6EPH receptor A6. (1169 aa)
NRP2Neuropilin 2. (992 aa)
ARTNArtemin. (220 aa)
LHX3LIM homeobox 3. (403 aa)
ENAHENAH actin regulator. (856 aa)
EFNA2Ephrin A2; Belongs to the ephrin family. (263 aa)
CNTN5Contactin 5. (1100 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
EFNB3Ephrin RBD domain-containing protein; Belongs to the ephrin family. (340 aa)
DRGXUncharacterized protein. (264 aa)
NGFRNerve growth factor receptor. (421 aa)
ARHGAP35Rho GTPase activating protein 35. (1500 aa)
GATA3GATA binding protein 3. (444 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
SEMA6CSemaphorin 6C; Belongs to the semaphorin family. (1023 aa)
CDK5R2Cyclin-dependent kinase 5 activator. (370 aa)
DLX5Homeobox domain-containing protein. (289 aa)
EFNA4Ephrin RBD domain-containing protein; Belongs to the ephrin family. (314 aa)
ROBO2Roundabout guidance receptor 2. (1439 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1216 aa)
EPHB1EPH receptor B1. (984 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (228 aa)
ARXAristaless related homeobox. (562 aa)
CRMP1Collapsin response mediator protein 1. (686 aa)
PALLDPalladin, cytoskeletal associated protein. (1404 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
SEMA5ASemaphorin 5A. (1116 aa)
ROBO3Roundabout guidance receptor 3. (1383 aa)
LHX2LIM homeobox 2. (406 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (785 aa)
ALCAMActivated leukocyte cell adhesion molecule. (583 aa)
PAX6Paired box 6. (437 aa)
EPHA1EPH receptor A1. (976 aa)
VASPVasodilator stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (383 aa)
DVL1Dishevelled segment polarity protein 1. (700 aa)
M3W868_FELCATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
EPHA4EPH receptor A4. (986 aa)
HOXA2Homeobox A2. (376 aa)
SEMA7ASemaphorin 7A; Belongs to the semaphorin family. (769 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
EGR2Early growth response 2. (541 aa)
L1CAML1 cell adhesion molecule. (1340 aa)
LAMA1Laminin subunit alpha 1. (3080 aa)
NKX2-2NK2 homeobox 2. (273 aa)
EPHB3EPH receptor B3. (1000 aa)
B3GNT2Hexosyltransferase. (397 aa)
LAMA3Laminin subunit alpha 3. (3332 aa)
LAMB2Laminin subunit beta 2. (1801 aa)
EPHA2EPH receptor A2. (936 aa)
LAMC2Laminin subunit gamma 2. (1191 aa)
SLIT3Slit guidance ligand 3. (1530 aa)
TTC8Tetratricopeptide repeat domain 8. (515 aa)
ISL1ISL LIM homeobox 1. (349 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
PLXNB2Plexin B2. (1841 aa)
GLI3GLI family zinc finger 3. (1578 aa)
RHOHRas homolog family member H. (191 aa)
DCCDCC netrin 1 receptor. (1446 aa)
GBX1Gastrulation brain homeobox 1. (362 aa)
FEZF1FEZ family zinc finger 1. (475 aa)
ROBO1Roundabout guidance receptor 1. (1550 aa)
ECE1Endothelin converting enzyme 1. (754 aa)
EDN1Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. (201 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (333 aa)
MYOTMyotilin. (460 aa)
SEMA4GSemaphorin 4G; Belongs to the semaphorin family. (840 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (768 aa)
EPHA7EPH receptor A7. (1000 aa)
B4GAT1Beta-1,4-glucuronyltransferase 1. (415 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (775 aa)
EVX1Even-skipped homeobox 1. (404 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (963 aa)
M3WUK9_FELCAUncharacterized protein. (166 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (749 aa)
USP33Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (912 aa)
OTX2Orthodenticle homeobox 2. (289 aa)
FLRT2Fibronectin leucine rich transmembrane protein 2. (630 aa)
EPHA8EPH receptor A8. (1003 aa)
NTN5Netrin 5. (489 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
PKHD1L1PKHD1 like 1. (4242 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
ENSFCAP0000002360360S ribosomal protein L24. (147 aa)
SEMA3DSemaphorin 3D; Belongs to the semaphorin family. (798 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (773 aa)
SEMA4BSemaphorin 4B; Belongs to the semaphorin family. (835 aa)
UNC5BUnc-5 netrin receptor B. (945 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1047 aa)
RTN4RL1Reticulon 4 receptor like 1. (445 aa)
BOCBOC cell adhesion associated, oncogene regulated. (1112 aa)
GAP43Neuromodulin; This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction (By similarity). (242 aa)
LRTM1Leucine rich repeats and transmembrane domains 1. (345 aa)
ARHGEF25DH domain-containing protein. (619 aa)
CRPPACDP-L-ribitol pyrophosphorylase A. (447 aa)
UNC5AUnc-5 netrin receptor A. (898 aa)
KIF5CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (957 aa)
RTN4RReticulon 4 receptor. (474 aa)
EPHA3EPH receptor A3. (984 aa)
DPYSL5Dihydropyrimidinase like 5. (604 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
EPHA10EPH receptor A10. (1008 aa)
EPHB2EPH receptor B2. (899 aa)
RNF165Ring finger protein 165. (683 aa)
KIF5AKinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1039 aa)
PLXNC1Plexin C1. (1576 aa)
GDNFGlial cell derived neurotrophic factor. (211 aa)
NKX2-1NK2 homeobox 1. (399 aa)
SEMA6DSemaphorin 6D; Belongs to the semaphorin family. (1069 aa)
LHX4LIM homeobox 4. (390 aa)
CNTN1Contactin 1. (1018 aa)
GBX2Gastrulation brain homeobox 2. (348 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
NEO1Neogenin 1. (1480 aa)
NEXNNexilin F-actin binding protein. (676 aa)
PLXNA2Plexin A2. (1911 aa)
EPHA5EPH receptor A5. (1043 aa)
VAX1Ventral anterior homeobox 1. (372 aa)
UNC5CUnc-5 netrin receptor C. (931 aa)
LHX9LIM homeobox 9. (487 aa)
NFASCNeurofascin. (1469 aa)
LGI1Leucine-rich glioma-inactivated protein 1. (557 aa)
EPHB4EPH receptor B4. (987 aa)
NRCAMNeuronal cell adhesion molecule. (1211 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (588 aa)
LHX1LIM homeobox 1. (406 aa)
ATOH1Atonal bHLH transcription factor 1. (356 aa)
SLIT2Slit guidance ligand 2. (1543 aa)
CNTN6Contactin 6. (1060 aa)
BCL11BUncharacterized protein. (895 aa)
PLXNA4Plexin A4. (1893 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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