STRINGSTRING
PLXND1 PLXND1 CHCHD6 CHCHD6 TGFB1 TGFB1 PAX6 PAX6 LAMA1 LAMA1 TGFB3 TGFB3 SEMA3C SEMA3C FGF7 FGF7 TWSG1 TWSG1 DAG1 DAG1 EDAR EDAR EDA EDA ESRP2 ESRP2 TGFB2 TGFB2 FGF10 FGF10 TNF TNF SELENOH SELENOH TGM2 TGM2 NFIB NFIB POLB POLB NKX3-1 NKX3-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLXND1Plexin D1. (1927 aa)
CHCHD6MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (2112 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
PAX6Paired box 6. (437 aa)
LAMA1Laminin subunit alpha 1. (3080 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (749 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (223 aa)
DAG1Peptidase S72 domain-containing protein. (892 aa)
EDAREctodysplasin A receptor. (447 aa)
EDAEctodysplasin A; Belongs to the tumor necrosis factor family. (388 aa)
ESRP2Epithelial splicing regulatory protein 2. (726 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (321 aa)
SELENOHSelenoprotein H. (121 aa)
TGM2Transglutaminase 2. (733 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
POLBDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (428 aa)
NKX3-1NK3 homeobox 1. (231 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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