STRINGSTRING
PMAIP1 PMAIP1 BCL2L11 BCL2L11 STPG1 STPG1 AIFM2 AIFM2 ENSFCAP00000054708 ENSFCAP00000054708 BID BID BAX BAX NAIF1 NAIF1 THEM4 THEM4 RHOT2 RHOT2 CCAR2 CCAR2 HK2 HK2 GGCT GGCT NDUFS1 NDUFS1 HSPD1 HSPD1 VDAC2 VDAC2 ATF2 ATF2 BNIP3L BNIP3L PPIF PPIF ENSFCAP00000025816 ENSFCAP00000025816 BOK BOK IFI6 IFI6 BIK BIK EYA2 EYA2 VPS35 VPS35 BNIP3 BNIP3 TIMM50 TIMM50 SFN SFN NOL3 NOL3 BAK1 BAK1 ENSFCAP00000039745 ENSFCAP00000039745 ENSFCAP00000040280 ENSFCAP00000040280 FIS1 FIS1 ERBB4 ERBB4 ATP2A1 ATP2A1 GCLM GCLM RHOT1 RHOT1 TP53 TP53 BBC3 BBC3 ATG3 ATG3 BAD BAD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PMAIP1Phorbol-12-myristate-13-acetate-induced protein 1. (54 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (196 aa)
STPG1Sperm tail PG-rich repeat containing 1. (356 aa)
AIFM2Apoptosis inducing factor mitochondria associated 2. (491 aa)
ENSFCAP00000054708Uncharacterized protein. (102 aa)
BIDBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (205 aa)
BAXBCL2 associated X, apoptosis regulator. (192 aa)
NAIF1Nuclear apoptosis inducing factor 1. (327 aa)
THEM4Thioesterase superfamily member 4. (238 aa)
RHOT2Ras homolog family member T2. (722 aa)
CCAR2Cell cycle and apoptosis regulator 2. (918 aa)
HK2Hexokinase 2. (917 aa)
GGCTUncharacterized protein. (188 aa)
NDUFS1NADH:ubiquinone oxidoreductase core subunit S1. (691 aa)
HSPD1Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family. (573 aa)
VDAC2Voltage dependent anion channel 2. (294 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (504 aa)
BNIP3LBCL2 interacting protein 3 like. (219 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (204 aa)
ENSFCAP00000025816Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (145 aa)
BOKBCL2 family apoptosis regulator BOK. (320 aa)
IFI6Interferon alpha inducible protein 6. (149 aa)
BIKUncharacterized protein. (245 aa)
EYA2Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (657 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (803 aa)
BNIP3BCL2 interacting protein 3. (187 aa)
TIMM50Translocase of inner mitochondrial membrane 50. (608 aa)
SFNStratifin; Belongs to the 14-3-3 family. (252 aa)
NOL3Nucleolar protein 3. (218 aa)
BAK1BCL2 antagonist/killer 1. (251 aa)
ENSFCAP00000039745Uncharacterized protein. (55 aa)
ENSFCAP00000040280Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (127 aa)
FIS1Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1049 aa)
GCLMGlutamate-cysteine ligase modifier subunit. (274 aa)
RHOT1Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (720 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (518 aa)
BBC3Uncharacterized protein. (193 aa)
ATG3Autophagy-related protein 3. (333 aa)
BADBCL2 associated agonist of cell death. (273 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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