50 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MTHFSD	Methenyltetrahydrofolate synthetase domain containing. (395 aa)
	SIM2	SIM bHLH transcription factor 2. (668 aa)
	TDRD6	Tudor domain containing 6. (2122 aa)
	TASOR	Transcription activation suppressor. (1665 aa)
	MEIS2	Meis homeobox 2. (477 aa)
	PLD6	Phospholipase D family member 6. (229 aa)
	TDRD1	Tudor domain containing 1. (1261 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	MEIS3	Homeobox domain-containing protein. (377 aa)
	MEIS1	Meis homeobox 1. (465 aa)
	NRARP	NOTCH regulated ankyrin repeat protein. (114 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa)
	SMAD3	Mothers against decapentaplegic homolog. (457 aa)
	RIPPLY1	Ripply transcriptional repressor 1. (186 aa)
	DISP1	Dispatched RND transporter family member 1. (1508 aa)
	ENSFCAP00000053647	Uncharacterized protein. (525 aa)
	ZIC3	Zic family member 3. (553 aa)
	PGAP1	GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic reticulum to the Golgi. (922 aa)
	TBX3	T-box transcription factor 3. (745 aa)
	NRP2	Neuropilin 2. (992 aa)
	PCSK6	Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (963 aa)
	PTCH1	Patched 1. (1451 aa)
	TBX6	T-box transcription factor 6. (436 aa)
	TIFAB	TIFA inhibitor. (214 aa)
	RIPPLY3	Uncharacterized protein. (262 aa)
	ERBB4	Receptor protein-tyrosine kinase. (1308 aa)
	CHRDL1	Chordin like 1. (602 aa)
	FRS2	Fibroblast growth factor receptor substrate 2. (543 aa)
	COBL	Cordon-bleu WH2 repeat protein. (395 aa)
	LHX1	LIM homeobox 1. (406 aa)
	EFNB1	Ephrin B1. (427 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (556 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (731 aa)
	TDRD15	Tudor domain containing 15. (2093 aa)
	NEUROG1	Neurogenin 1. (243 aa)
	WNT1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
	NODAL	Nodal growth differentiation factor. (348 aa)
	NANOG	Nanog homeobox. (311 aa)
	TDRD5	Tudor domain containing 5. (1034 aa)
	OOEP	Oocyte-expressed protein homolog; As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions; Belongs to the KHDC1 family. (149 aa)
	SEMA3F	Semaphorin 3F; Belongs to the semaphorin family. (785 aa)
	MESP1	Mesoderm posterior bHLH transcription factor 1. (261 aa)
	KDM6A	Lysine demethylase 6A. (1453 aa)
	MEOX1	Mesenchyme homeobox 1. (307 aa)
	TDRKH	Tudor and KH domain containing. (562 aa)
	SMAD6	Mothers against decapentaplegic homolog. (497 aa)
	RIPPLY2	Ripply transcriptional repressor 2. (169 aa)
	IHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
	LOC101084379	Homeobox domain-containing protein. (290 aa)
	ZBTB16	Zinc finger and BTB domain containing 16. (679 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DISP1	IHH	ENSFCAP00000054131	ENSFCAP00000017498	Dispatched RND transporter family member 1.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.843
DISP1	SHH	ENSFCAP00000054131	ENSFCAP00000061011	Dispatched RND transporter family member 1.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.843
DLL1	NRARP	ENSFCAP00000059464	ENSFCAP00000032288	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	NOTCH regulated ankyrin repeat protein.	0.529
DLL1	TBX6	ENSFCAP00000059464	ENSFCAP00000044519	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	T-box transcription factor 6.	0.416
ERBB4	FGF10	ENSFCAP00000042375	ENSFCAP00000032796	Receptor protein-tyrosine kinase.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.692
FGF10	ERBB4	ENSFCAP00000032796	ENSFCAP00000042375	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Receptor protein-tyrosine kinase.	0.692
FGF10	FRS2	ENSFCAP00000032796	ENSFCAP00000039800	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor substrate 2.	0.672
FGF10	IHH	ENSFCAP00000032796	ENSFCAP00000017498	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.753
FGF10	NANOG	ENSFCAP00000032796	ENSFCAP00000001505	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Nanog homeobox.	0.491
FGF10	SHH	ENSFCAP00000032796	ENSFCAP00000061011	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.764
FRS2	FGF10	ENSFCAP00000039800	ENSFCAP00000032796	Fibroblast growth factor receptor substrate 2.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.672
IHH	DISP1	ENSFCAP00000017498	ENSFCAP00000054131	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Dispatched RND transporter family member 1.	0.843
IHH	FGF10	ENSFCAP00000017498	ENSFCAP00000032796	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.753
IHH	PTCH1	ENSFCAP00000017498	ENSFCAP00000044951	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Patched 1.	0.988
IHH	SHH	ENSFCAP00000017498	ENSFCAP00000061011	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.906
IHH	WNT1	ENSFCAP00000017498	ENSFCAP00000000081	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.552
LHX1	TBX6	ENSFCAP00000039659	ENSFCAP00000044519	LIM homeobox 1.	T-box transcription factor 6.	0.435
LOC101084379	NANOG	ENSFCAP00000018204	ENSFCAP00000001505	Homeobox domain-containing protein.	Nanog homeobox.	0.900
LOC101084379	NODAL	ENSFCAP00000018204	ENSFCAP00000001141	Homeobox domain-containing protein.	Nodal growth differentiation factor.	0.482
LOC101084379	TBX3	ENSFCAP00000018204	ENSFCAP00000048975	Homeobox domain-containing protein.	T-box transcription factor 3.	0.699